Can a non chiral object be made of two identical chiral moieties?
7
0
0
Texte intégral
(2)
(3) !#"$%& '( ) &* +(&-,/. 01 24365781:94;)<=1?>A@@CB D*EF?G'HAII J#HAICKA1 0L5-M:NO P(MNQRAS&TVUW5/XZY\[]942_^`YaU bcNSed5PfT(Shgji ;5kUlRANDm]=Rno5qprR*Pj7`Mn&5%s<AtAiP(So5L<AP(5 ;5kU_l6RCN6D HAu`Mnvni5 ;'wox#gjMnoS5DCuyIuHADUzc{kprD)O'[ Y]pr2_9 |~}LoL sA5/dA5P(Mn't'5-;MAR*ASo=Mn R 5?=/g(T]=MN 5\< T5;gR;S&T(=L<TLT4=3SoP(Mn&Shgl16^$5P(5-D$5\< T5\g35%=L<gRMNMttCn5 gRTj3Rg3M/gg35M)TLT(RA=SoM/gjSoRNRS&;5N?gSo=-M:n=3SP(Mn7`RASo5/gjSo5)TZ=MNRP(7 MN6R*N=3SvPM:nR 5=/g1 {=/gjM35-;P(MnA=:3SPfMnoShglrST!< T(5;~gjR%#SoNA;T(Shg+<M/gSeR*N'T5-)<'SdMno5N)g gR g35 =/<gR*'g365 MttCne51 # ¢¡¤£ L¥ ¦ sA5=RN;J#zc5MP§bcN;5PjP(M;)<M/gj5DxN6R*PjMNS=¨2k365:7rS+T#gPl6D©YNMnoRCS5T(Dª2kRRP(;SoNMLgSoRN 2]R*7ctAR6<AN6;TDC2q3SoP(Mn&Shgl6DC{=/gjM365;P(MnA=3SoP(Mn&Shgl6D69WNMN)gjSR*7$R*Pt36D sl677r5/gPl6D6«cSoN w#T=/<g v#¬ x#gS&T=RC7`7`RCN tCnM=5`35N§gj5M=3SoN®=:3SoP(MnShg#l¯gjR°<T(5±7rM/gj5PjS&Mn`R 5=/g(T8gRSonne< TgP(M/gj5©g365±So;5MT SoNdARCnd5;8SoNg3S+T];RC7`MSoNRC=357rSTgPl'1A2]3SvPM:nShglSTqg365~tP(RtA5P+g+l8R7`RCn5=/<n56T4R*P4R6 (5-=/g(T_`3S=3 MP(5NRNT#<AtA5P²So7`tAR'T(M An5³RN´g365:SP
(4) 7`SoPP(RP(J#So7rMA51qµ¯3S&n5tAM:SoPfTRC`=3SoP(Mna¶c·¸&¹º»¸¹¼MP5³=Mn&n5; 5N6M:N?gSeRC7`5PfTDt'MSPTRC]=3SoP(Mn½¶¾¿v¹ÀLÁv¾A¸·AÂ&ù?º?¿¼D_T< =3M)T\=Pl'T#gjMn&TD_MP(5=Mnn&5-;©5N6M:N?gSeRC7`RPt3CT%ÄÅÆ'1 Y`T~jMPM)Tc7`RCn5=/<n5TMP(58=RNA=5P(N65;D_=3SPM:nShgl³n5?M;'TagjR
(5) g35tP(RtA5P+g+lRAk 5SoNRtgSo=MnnvlªM=LgSdA5-D c3S&=3®=R*NAT(S+T#g(TSoN 5SoNÇM An5´gjRPjR)gjMÈgj5©g365´tAnM:NA5ZR8tARCnoMP(SÉ 5;nSvA3)g1csC5LdA5P(Mn`5Ê*M:7`tAn56TRC 7rM/gj5P(SoMnR f5-=/g(Tk<!T(5-;ËgjR35not
(6) gj5M=38g358=RN=5tg¤R~T<AtA5P(Sv7`tAR'T(M AS&noShgl3AMdA5 A5-5:NtP(5T(5N?gj5;S&N g3S&T Ì·»Àf;A¸j1qÎV3S+Tr=R*N6=?5tgjD4c3So=3±S+T`tASdARgjM:n¤R*P`n5MP(NSoNÏ=:3SPfMnoShglADa36M)T 5-5:NZSoN)gP(RA;)<=5;³ Al M)TjÐCSoNÑT#g+<;5N?g(T³gRÒ=RNCT(Se;C5P³g365tP(RtA5PgSe5)TZRCg&$RÓSe;5:N?gSe=Mn
(7) ARAR*Ð'Tg3MLg=-MN¨no5?M;ÔgRÔg35 =RN=nh<!T(SoRCNg36M/gVg35~ ARARÐ'T¤MP(5D SoN;55-;Dg35TM:7r5ÄÖÕ²Æ'1{kg35P¤5/Ê*M7tAn5)T¤R_tA5;AMARS=MngjRRn+T¤MP(5 tAnoMSvNS;A5:N?gS=Mn;*S+T(3A5)Tag36M/g¤3M/d58Mn+T(R A55N
(8) < T5;
(9) gRSoN)gP(RA;)<=5%g35NR)gSeR*NR T#<At5P(So7tAR'T(M ASon&S×g#l1 ÎV35SP`T#gjM=ÐASoNª7MÐA5)T`T#<AtA5P(So7`tARTM- ASnoShg#l©Mtt'MP(5N)gØMN6;
(10) g35lª=MN A58;S&5P(5N)gjSoM/gj5;
(11) lª7rMPÐASvN g357¨Ä+ÙÆ1ÎV35%T(M7r5$TR6<AP=5 MnTR$< T56TN6M/<gSon<!TqT(3A5nvnTqTtAn&S×gVSoN3AMno gjRSon&n< TgP(M/gj5 5N6M:N?gSeRC7`RPt3CTÈ1)x(N g3S&TcMP#gjSo=n5D½$5$S&non_<!T(5g355-Ê*M7tAn5
(12) RA =/<g+gSoNÚMttCno5TcM)TcM
(13) 7r5/gjMt36R*PcR*Pag365
(14) M)TT(RA=S&MLgSoR*NªRC =3SoP(MnA=?5N)gj5PfTÈ1 ÎV35=3SoP(Mn&S×g#lÛR*¤MNR6 5=/gk=MN
(15) A5S;5N)gjSoS5;
(16) l=R7`tAMP(SoN©S×gq`Shgj3Shg(T 7rSoPP(RP(J#So7rMA5
(17) Ä&F(Æ6D <g¤M 7`RP(5´TgP(MSA3)gjRP#`MP(;´$M/l§S+T`gjR´< T(5Tl7r75LgPlÏ=-R*NAT(So;C5P(M/gSoRN'TL1_X´R*no5-=/<'n5T`g3M/g`36M/dA5tCnMN5TD =5N?gj5PfTDkRP`Mn×gj5PNMLgSoNZMÊ*56T$=MNNRg A5=3SoP(Mn~ÄÜ(ÆD]MN6;±7`R'T#gcRag35ËgjSo75-DkRNnvlªg35©TlA7r7r5/gPl tAnoMN5R*tA5PM/gSoRNS+TW=R*NAT(S;5P(5;'1xg=MNrMn&TR A5~365:notA#<n'R*P]T#g+<;5N)g(TgRno5MP(N36R6gRP(5-=RNSÉ?5ag35 tAR'TfT(S An5 =:3SP(Mn'=5N?gj5PfTR7`RAno5=/<n56TÈ1 Yag]T(=36RCRnoD =3SoP(Mn&ShglS+T]RC&gj5N8SvN?gP(RA;)<=5;`Shg3MTl77r5/gP(So=-M:n!=MP *R*NM/gjR7T(DC`3S=38MP5c *MT(S&=cM:NA; +P(5)<5N)gnlÏRA==/<APP(SoNÏ=3SPM:nØ=5N)gj5PT(D4 <g%7$M:NlÏRg+365P8T(Shg+<M/gjSoRNCTr7MlÏMP(S+T(5 1qÎV3A5Ût36RTjtC36R*PjR< T M/gR*7¨SoNtA3R'Tt3SoNA5%7rM-l8 *5%M%=3SoP(Mn!=5N)gj5P]MN;87`RCn5=L<'no5T]7rMlrtP(5)T5N)gWM%=3SP(Mn MÊAS+T(DT#<=38MT]SoN Mnon&5N656TD
(18) ASvtA35NlAn5T¯RP°TjtCSP(MN5)TÈ1X´RCno5=L<'n5T±`S×g3ÑMÔ3A5noS=)MnT#gP<=Èg+<AP(5Mn&T(RÝ5/ÊAS+T#gjD³T<=3ÑMT Þ N6ß#35n&S=?5N5àN~áuâWRPq7`RCno5-=/<'n5TWRCV3SoC365PW=RC7%tAn5-ÊAS×g#lT#<=3rM6T]TgjMP(=3Ä#ãÆDä pY®R*PtP(R)gj5SoNATL1x(N SoNRPAMNS=
(19) =RA7%tCn5ÊA5?T(D_µ¯5PNA5Pc;5:7$R*NAT#gP(M/gj5-;g36M/g¤RA=ÈgjM35;P(MnW=RC7%tAn5ÊA5Tc=R6<Ane;© A5=:3SoP(MnaÄåæç(Æ lP(5)T(RAnedASoN2]RAà&p%^%èâà2qnâ(à^cé+pr2W^cé(2_^cé+p$^céâé]g35N6D½nM/gj5P(DV2qRêà{a^câë(à&p%^%èâLì&é1C^$55/d*5:NtP(RdA5; `Shg3g35 noM/g+gj5P'g3MLgV5NMN?gSoRA7`5Pl`=-R6<no;`RC=-=/<APVSoNTtA5?=So5Tg3MLgV=RN)gjMSoN%N6R=MP ARN`M/gR78TL1 ÎV35M)TLT(RA=SoM/gjSoR*NrR g+$R8=3SP(Mn =-5:N?gj5PfTV`Shg3SoNR*N65~78Rno5=/<n5~=?MNn5M-;$gjRSN?gj5P(5)TgSoN=M)T56TÈ1µ¯35N g+cR+P(MA75N?g(T`RMÛ7$RCn5=/<n&5MP5 *R6g3Ú=3SPMn¤M:N6;±7`SoPP(RP%So7MA56TDkRP`5/Ê*M:7`tAn5˶%¹¼È·æ#gjMP+gjMPSo=.
(20) M=So;Dg35kc3RCne5\7`RAn&5-=/<'n5 S+TVNRg =3SP(Mn+1 ν365\SoPfT#g!tAMP+gR*'g3S+TVtAMtA5P)<5?T#gSoRN'Tg35 =-R*N?dA5PfT5 RC'g35 tP(5/dASeR6< T¤T#gjM/gj57$5:N?gjD'S+1×51×DS×gM)TjÐ'T(D'SoqM~N6R*N=3SP(Mn 7`RCn5=/<n5$S+TW7M-;C5RC g+$R8=3SPM:n=)5N?gj5PfT(D;RC5)TShg RCnonoR*¨g36M/g_g365)T(5r=5N?gj5PfT 7~< Tgq A57`SoPP(RP]So7M'5)TØR]5?M=3R)g365P xNR6g365PkcRP(;CT(D'`5%%SonnVnoRCRÐ RPM =R6<AN?gj5P(5/Ê*M7%tCn5kg36M/gT3RrTV3R MaN6R*N`=3SPM:nR (5=/gT#<=3`MTMN`MttAn5 =MN% A5~TtAn&S×gVSoN)gjR~g+cR S;5N)gjSo=Mn'=3SoP(MnR6 5=/g(TÈ1ÎV35N6DCSoN$g365~T(5?=RN;%tAMP#g R* g35atAMtA5PD6$5k`Son&n=RC7%tAMP(5kg35atMP#g(TR'g35 MttAno5k`Shgj3`RA=ÈgjM35;P(MnA=RA7%tCn5ÊA5TÈ1
(21) ] Y7`RCN%g365k`Ml'TWSoN$$3S&=3%tA5-R*tAno5 =/<g g35SPMttCn5)TD'R*N65 ;5)T(5Pd*5)T]TtA5=SMn'MLg+gj5N)gSoRNDAM)TShg n&5-M;CTgjR g+cR³5no5AMN)g¤tRP+gSoR*NATag3MLgaShg]gRA5fg35PM)TSoNMg3 P(558;Sv7r5NCT(SeRCNMnt<AÉÉ?n&5 1§ÎV3ST¤`MlÛRC¤=/<g&gSoN MttAno5TaS+T¤NM7r5;g35ÁvÍ ¼º»A¿V;)<5~gjRg35`no5A5N;Ëg36M/gWShg_$M)T]tP(5?T(5N)gj5;gRM~«%SoN SoNM%P(57`Rgj5 =R<AN)gP#l1Î_R=-MPP#lËR6<g4M~«%SoN w#T¤=/<gjDVT#gjMP+g l=/<g+gSoNM%dA5P#gS=Mn )<MP#gj5P¤;R%N+P(R7Óg35TgjM:nÐR* g35`MttAno5D7$MPÐA5;`pÑSvNSv<AP5Û?1×M`àMnoRN8g35`nvSoNA5pY â(D'g35N=L<g]M%3RPSÉ:R*N?gjM:n 3AMno]ànoSvNA5`Y2qâ(D g35NMd*5P#gjSo=Mn)<MP#gj5PØà#noSoNA52 sâ ;R%N8gRËg365$ *R6gg+R7ÑR_g365+P#<'S×gjD g35NMneM6Tg]3Mno¤àn&SoNA5
(22) säØpâ AM-=ÐgjRg35TgjMnÐ 1Aν3S+T¤=/<gV`Sonon 5c=R*NAT(S;5P(5;85Shgj3A5P]M)Tg35T(SÊMP=6T pYD YØDØ2]D 2 sADVsä¨MN; äØpDAR*PM?T½g365kp`YØ2 s6äØp¨n&SoNA5~SoN%g35~RCnonoR`SoN 1prR*N65~R g365)T(5=/<g(T]T36R6<no;r=P(R'TfTW5M=3rRg35PÈ1)x g35k AnM;5Rg365\ÐANSo5=/<g(Tg365 MttAn&5 M?Tq;5-5tCnolrMTg35 7S;;n5 M-ÊAS+TWRC'g35 +P#<ShgjD* <gN6R6g!7`RP(5D)g365 g+cRtSe5=5T=MN% 5~T(5tAMP(M/gj5;'1Ø5CSoNN65PLT_7`SoA3)g P(5-M:Ð%g365 MttCne5 R*PVA5/g!N6R*N%tA5PtA5N;S=/<n&MPVtCS5=5TD <g!tP(M-=ÈgSo=?5~TRCRN%7`MÐA5TVtA5P²5-=/g1 N. N. C. C D. B. B A. A. àjMâ. D. S. S. OSo 1 OPR7g35~TjtC365P(5kgR g35 =/<g!tSo5=-5)TRC'g35 MttCno5 1. à â. a{ T(5P#dASoNÚR*N65
(23) RC]g358tCSe5)=-5)TT(36R6<Ano;±T(36R6Òg3M/gØShg S+Tc=3SoP(MnoDq5d5N³M?TLT#<7SoNg35MttCn5gjR© A5M tA5Pj5=/gTjt3A5P(51 x#g36M)TNRTl7r7r5/gPltAnMN5D`NRÔSo7`tP(RtA5PM/ÊAS+T(D`MN;°g365P(5§S+T³N6R6g5LdA5N MNl Tl7r7r5/gPl8RtA5P(MLgSoR*NR)g35PVg3MNM%2q>M/ÊAS+TL1AÎ_35c24>M/ÊAS+TqtAMTT5)T]+P(RC7Ôg365%7S;;n5%RCg35%noSoNA5apr2 g3PR6<A3`g35`=5N)gP(5-DMN6;
(24) R<g4MAMSoNM/gg35`7S;;n5RAknoSoNA58sCY`1ν365P(5R*P5Shg A5noRCN 'TqgjRg365`=3SoP(Mn tARSvN?g PjR6<AtÚ2qéL1V{a 'T(5P#dASoN³ ARg3©tASo5=-56TtP(RdA5?T\g3AMLgkg365lªMP(5
(25) S;5N)gjSo=MnD_tP(RdASo;5;g35MttCn5
(26) S+T M)TT#<75-;ËgjRË A58Tt3A5P(So=?MnoDVMN;8g35ÁoÍ ¼%º-»A¿ $M)T¤tP(R*tA5LPnlÛ=MPP(S5;R<g1 R)g3MP(5`7`M;5rR*_g+$R )<MP#gj5PfT R MN MttAn5 t'5PtA5N;S=/<n&MP²nol MTfT5:7` An5; SoN g35 TM:7r5 $Ml à#OS 1L âÈ1ÎV35 5N6M:N?gSeRC7`RPt3R< TtCSe5=5Tª=R<'no; 3MdA5§ A55NÇtP(RA;)<=5; l tA5P(R*P(7`SoN g365¯R6g365P ~ÁoÍ ¼Zº»A¿ ¦ p`Yaär2 s WpàO!Sv 1 >âL1. >.
(27) O!So 1)> rÎV35aP(5?T#<nhg!Rg365kg+cRt6RTTS An5Ø«cSoNw+T=/<g(TÈ1ÎV35kg+cR%tSo5=?5)T½R*'g35alA5nonoR MttAn5 MP(5 =3SoP(MnAMN;`S;5:N?gSe=Mn&DAMN6;7SPP(RPVSv7rMA5TR'g35atASo5=5TR'g35aP(5-;Mttno51 ÎV35³MT(=SoNAM/gjSvN ±g3SoN¯M *R6<gg35 ~ÁoÍ ¼º»A¿\S+T`g3M/g$Shg`S+Tg365³=R<AN)gj5P(5/ÊAM7%tAn5Û$5³7r5:N?gSeR*N65); 5MP(noS5P(D!M)TaS×g]MPjS&T5)T¤+P(RC7g35`M=/gVg3MLg]MNM-=3SoP(MnR 5=/g4àÖg365`MttCne5â¤=MN 5$tAMP#gShgSoRNA5;
(28) SoN)gjRg+cR Á ¹Í¿vÁ&º¾A¸a=3SvPM:nWtCS5=5TÈ1½Y¨< T#<Mn]MN;5-M)Tlªt'MPgShgSeR*NªRCØM:NªM=3SoP(Mn]R 5=/gà(T(MlÚM
(29) 3)<7rM:N ARA;6l â n5M;'TVgR8M no5&gMN;rM\P(SA3)g tAMP#g(1¤R)g3r=3SoP(MnT(3MP56TWMP(55NMN?gSoRA7`R*Pjt3CTL1 xN%g35=M)T5R* g35~ÁoÍ ¼ º»A¿D6g365atCSo5-=5TMP(5kg365$TM:7r51?xN~g365k`RP(no;`RC7$RCn5=<'no5TDCMk¶c¹¼L·T#gj5P5R*ST(RC7`5PqT#<=3rM)Tg35k¶$¹¼L·AJ gjMP+gjM/PjS&=rM=S;ÛS+T 7rM;5rRC]MN8[=:3SoP(Mn=5N?gj5P MN6;MNsRN5 !NRg_g+cRªsRN5)TÈ1ν365ÁvÍ ¼%º»A¿S#T g35P(5R*P(5a3SC3nol`SoN)gP(S<SvN 1 'C¤ +v#¬ $
(30) ] ' {=/gjM35-;P(Mn =RC7%tAn5ÊA5)T]36M-d*5%M~j5/5MLg+<AP(5)TqSoN=RC7`7`RCN%`Shgj38MÁvÍ ¼Øº»A¿#162kRA7%tCn5ÊA5?T]7M-;5~RC g3P55 =3A5nM/gSoN8;So3AMtgjRnoSoAMN;'T(D'T#<=3rM)TW5/g3ln5N;SM)7rSvNA5 àj5:N â(DAMP(5 RC&gj5N`R<'N6;SoN%<'N6;5PP(M-;)<M/gj5 gj5/Ê g+ ARRÐ'TL1^cR6$5/dA5P(D6g365P(5 MP5~Mn+T(RrR)g35PVÐASoNA;CTqR=3SoP(MnRC=/gjM35;P(Mn=RC7%tAn5ÊA5T(D'T(RC7$5~R `3S=3 MP(5 ;S+T=/<TT(5;% A5noR81 ÎV35SPVP(5noM/gjSoRN~gjR\g365 ~ÁoÍ ¼]º»A¿AST½5/ÊM7SoNA5?;'1 . VÎ 35T(S7tAn5)T#gWRN5?T]MP(5 XZà5N â è RP_X´à2_^ è {~2_^ é 2_^ é {~2_^ è â è D M)TWSoNO!So 1hI'1AÎV35SP]=3SPM:nShglMn`Ml T gjMÐA5)TWT(R7`5kgSo7r5kgjR$ *5 5/dAS;5N)g gR8Tg+<;5N)g(T(DAMN6;Shg S&TWR*&gj5N`N65=5TfTMPl%gjR%P(5tP(5)T5N)g g365:7 MnoRAN%g35 2 è M/ÊAS+TRCqg358=-R*7%tAn5ÊA5TL1s<=3=RC7ctCn5ÊA5)T *5:neRCNgRtRSoN)g¤PR<Atä è DM)Tkg3658R*NnlTlA7r7r5/gPl RtA5P(MfgSoR*NAT`MP5g3 P(552 é MÊ5)Tt'5PtA5N;S=/<n&MP\gjRg357`MSoNZ2 è MÊAS+TL1VÎ_365
(31) NRA7`5N=nM/g+<AP(5R*]g35T(5 =R7%tAn&5Ê*56T¯< T(5T¯g35 ∆ Λ NR)gjMfgSoR*NATÄ Å Æ'1 xN g365 T(M7r5jM:7`SnvlAD=-RC7%tAn&5Ê*5)TÔT< =3 M)T XZàj2W^cè({2_^%é(2_^cé+prà2_^%èâjéâèWMP(5=3SP(Mn' <g!`Shg3rMN85/d*5:NrnoRr5P]TlA77r5/gP#l6D'MTVg35P5~S+TqRNnvlM%2qè M/ÊAS+TL1AY=-RC7%tAn&5ÊËR*Vg3S+T T(RPgV *5:neR*N TgjRËPjR6<At8t6R*SoN?gW24èÈ1CÎV35`T(S&7SnMP(Shg#lRCW=3SP(MnV=-R*7%tAn5Ê5)T]RC g3S&TÐASvNA;±`S×g3±g365±MttCn5tCS5=5?T=-M:N¯ A5§T(55N+P(R*7 g35ZN)<7$ 5PRCr=RC7`7`RCNÇTtA35P²S=Mn`MP(=)T SoNdARCnd5; ¦ prYD 2ÇMN6;©säÒà#O!So 1LâÈ1'ÎV35)T5MP(=?T 7rM-gj=3g3P(55`R_g358T(SÊRCVg35«cSoN w#T¤=/<g4à&pYD YØD Ø2]DA2\sAD sä`DMN6;~ä p`âL1aµ¯5 noRAR*ÐA5-;$RP!R)g35PnoSoAMN;'Tg3MLgV=R<Ano;ShgV7$R*P(5 1. I.
(32) NH2 NH2 H2 N. H2N. H2 N. N H2. H 2N. H 2N. NH2. N H2. NH2. N H2. !O So 1IrÎV35 RA=fgjM35;PM:n'TgP#<=/g+<6P(5aR'XZà5N âèMN6;Shg(TVdAS5/ +P(RC7g365 2qèM/ÊAS+TL1 Î $R~ ARN;CTMP5 5NnMPA5-;RP g35~TMÐA5 R=nMP(Shgl6D6 <g'g35 RA=ÈgjM35;P(RN%S+TVP(5<'nMPL1 ÎV35qp%^%éV+P(MC7r5N)g(TVtP5)T(5N?gj5;%SoN ARAno;M=?5 =RPP(5?TtRN;`SoN~g35kg+cR`;P(M/cSoN'TÈ1 ÎV352]Mà5-;)gjMâ é =R*7ctCn5ÊZS+T`7`R*P5ÛjM7`R< T`R*P`Shg(TrMN6Mnvl?gS=Ë<!T(58g3MNR*P`Shg(T$=3SPM:n]tP(RtA5P+g+l1½xg ;Svj5PfT]+P(RC7Çg35 XZà5Nâjèq=3SPMnoShg#lSoNgj35agjR*t6R*noRlrR*g365~n&SoAMN;
(33) T(SoNA=5cR*Nnol8RN5n&SoAMN;cP(Mt'TV<'t g357`5/gjMn =M/gjSoRN'1ÎV35`T#gP#<=fg+<AP(5R*T#<=38M=RC7%tAn5Ê$M)TWR6 gjM:SoN65;#PRC72]M Þ 2kM-à5;)gjMâ(ß1 )^cé({ÔÄÅÅÆ MN6;
(34) =RA7%tAMP(5;`Shg3Rg35PfT Ä#Å?Ü(Æ1'ÎV35`MNAn5)T¤RCVg35~ ARN;SoNMP(R6<AN6;g365`2kM`=MLgSoR*NMP(5MP¤+P(RC7 g35 y@ qSoN%g3A5 =Pl'TgjM:neD* <g SvNg35atP(Rt*l6n5:N6;*SM7SoNA5/gj5LgP(MM=5fgjMfgj5 à#tA;:gjMâVSeR*N6D6g365~T#gP#<=/g+<AP5aS&TWM:n7`R'T#g RA=ÈgjM365;P(MnAàO!So 1)HâÈ1:µ¯S×g3~g35aN6R6gjMfgSoRN`RC'g35k«cSoNw+TW=/<gD)g365 =R*7ctCn5Êr=MN% A5aP(5tP(5)T(5N?gj5;~ l~g3A5 p`YD½ä`YD_YØD Ø2kDWM:N6; ]ä MP(=?T%RAkg35TtA3A5P(5 1Y~n×g36R6<A3g35P(5
(35) MP(5
(36) 7`RP(5MP(=)T g3MN`Shgj3g35 XZàj5Nâè=-R*7%tAn5ÊADg35kgRtRnoR*l$Rg365 =R7%tCn5ÊrS+TqT#gSon&nA;S&j5P(5N)g +P(R*7g365k«%SoN!wT½=/<g1 O. O C. O. H2C O O. O Mg. C H2. N. C H2. C H2 C. CH2 N C H2 CH2. C O. O!So 1 H äcP(M/$SvN rR*'XAàtA;)gjMâV+P(R7 MN`{a[ Î9P(5tP5)T5ON)gjM/gSoRNÄÅ?Ü(ÆT36R6`SoN MaP5M)T(RNM An5 RA=ÈgjM365;P(MnA=3SPMnA=RC7%tAn5-Êc`Shg3`M~T(SoNAn&5 noSo'MN;~cP(MttASoN%<At%g35 =M/gSeR*N1 VÎ 35 n&M?T#g =R7%tCn5Ê%gjR~ A5 5Ê*M:7rSoNA5;365P(5 7SoA3)g A5 5ÊAtA5=Lgj5;\gR% A5kg365 =:neRT5)T#g gR g35 ÁvÍ ¼4º»A¿eGM)T g35~gR*t6R*noRlRA½g365noSoAM:N6;
(37) S+T¤MnoSoNA5?MP¤=3MSoN%< T#g]noSoÐA5~g35\gPM=5%R½g365~ An&M-;C5`R½g365$ÐNS5`RNg35 TÐASoN RC8g35¯MttAn&5 1%ÎV35°noSoAMN;ÔS+Tª=?Mnon&5-; tA5N)gjMCnlA7r5D2_^ è à{2_^ é 2_^ é â {2_^ è D+P(R7`3S=)3 =Mno=S<'7ÝMN6;ÛTgP(R*N?gSh<7Ñ=RC7ctCn5ÊA5)T]$5P(5%tP(5tAMP5;MN6 ; cJ#P(Ml=3AMP(M=Lgj5PSÉ 5;Ä#Å ÕÆ1COSd5%tAR'TfT(S An+5 A5R7`5/gP(So5)T¤=-M:NM~tP(SoRP²S' 5%=-R*NAT(S&;5P(5;8R*P]M%365-ÊM-;C5N?gjM/gj5~noSoNA5?MP]nvSoAMN;cP(MttASvN <AtMc=M/gjSoR*NM/g g35`prD_YD ØDq2]D½ä$DqMN;ZsRA=/gjM35-;P(Mn_tAR'T(ShgjSoR*N'TcRNg35©TjtC365P(5à< T(SoN©g35NRgjMÈgSoRNªR*aO!So 1 LâL1 ÎV35)T5$A5-RC7`5/gP(So5)T¤=-M:N8 A5`5N=-RC;5;M)TpYØ2_äs Ap`YØ2 sä pYcsA2_ä prY%sär2 6pY`s 2_ä àO!S 1K?âL1 ν365 5NMN)gjSoRC7`5P²S=~TgP#<=/g+<P5)T=MNrMn+T(R% A5 =RNCT(S;A5P(5;'1?Y~n×g36R6<A3~g365)T(5 Sd5%T#gP#<=fg+<AP(5)TMP(5 P(5noM/gjSdA5nvlË5M)TlrgjRËSo;5N?gSvlAD'tP(RdASvN g3M/g!g35P5%MP(5RNnvlSd5%RCg357¨S+T];S&S=/<nhg1b%NRP#g+<ANMLgj5:nl*D g35
(38) g3 SoRC=l*M:N6M/gj5=R<AN)gj5P`MNSoR*N'TrMn+T(RÏ=RRP(;SoNAM/gj5ËgÖ35=Mn=:S<7 =MLgSoRNZM)T8T(36R6cN´ lg365=Pl'T#gjMn T#gP<=Èg+<AP(5?1ªÎ½365Ñ2kM-à#tA5N)gjMAnlA75â(à&pr2\sâ é =-R*7%tAn5Ê A5/g(T *R6g3Ýg3SoRC=l*M:N6M/gjR noSoAMN;CTSvN gP(MNCT tAR'TShgjSoRN'T]à²T<=:3M)TVpÒMN;sSvNO!So 1VLâL1ÎV35%=-R*7%tAn5ÊT#gP<=/g+<P(5ST4=noRT5\gjRM%;S&T#gjRP+gj5;~p`YØ2WäËs H.
(39) «cSvN!w+T =/<gjD'%S×g3Ëg365SPLTg]MN6;©T(SÊgj3R6Êl6A5NM/gjR7TØR*Vg35r=3MSoN=noR T5`àM ARdA5MN8 A5noR%âqgjRg35 Y2_ä®tCnoMN6DCMN;~g365a>AJ²KRÊlA5N`SoN~g3S+TVtAn&MN1 N. N. D. N. D. B. B. D. B. S. S. S. N. D. N. B. S. D. B. S. O!So 1K ! R'TfT(S An5~T#gP<=Èg+<AP(5?TVR*PMN`RC=fgjM365;P(MnA=R7%tCnÖ5/Ê%`S×g3`M noSoNA5MPV35Ê*M;C5N?gjM/gj5knoSoAMN;'1 ν365 tARSoN)g(TVYà+P(RN)gâ MN;`2Zà AM=ÐâMP(5aNR)g!SoN;S=M/gj5;%RP g365~T(MÐA5 R!=:neMP(Shg#l1 {a<AP±SoNShgjSM:nSoN)gj5N?gSoRN`M?T´gjRÑ)<5?TgSeR*Ng35 =RNd5PfT5 tP(RtR'TS×gSoRNÒM==RP(;SoNÓgjR%3S=3g35 M)TT(RA=:SeM/gSeR*NÏRC~g+cR¯5N6M:N?gSoRC7`5P²S=³7`RAS&5LgSo5?TT(3R<Ano;°ne5M;´gjR¯MNÏM=3SPMn 7`RCn5?=/<n5D M)T8SoN§7r5T(RAJ gjMP+gjM/PjS&=M=S;'1µ5Ø$5P(5%SoN'TtASoP(5; l`gj355-ÊM7%tAn5%RCg365\«%SoN w#TW=/<g!gjR#SoNA;7`RAn&5-=/<'nMPVgjRtRnoR*ASo5T T(So7Sn&MP4gjRShg1CY7`RN8g35~g+l tARCnoR*lËRCq=3SPMnV=-5:N?gj5PfT¤àgj5fgP(M365;P(MnoD!=3SoP(MnVMÊAS+T(D5Lgj=1 â(D$5%RC=/< T5; RNRC=fgjM35-;P(Mn=3SoP(Mn&S×g#l6D$3S&=3noRAR*Ð'T¤=noR'T(5~gjRg35`MttCno5`=/<g1µ¯5`5ÊAM7rSvNA5-;g3 P(55~gjR*t6R*neR*ASo5T¤R* n&SoAMN;CTÈ1)94M=3rRC g3657n5;$gjRrM~=3SP(Mn =RC7%tAn5Êg36M/g `M?T½gRR8;S&TLT(S&7`Sn&MPq+P(RC7Çg35a«%SoN!wTW=/<g1?µ¯5 MP(5ag35P(5R*P(5no5;gjR A5noS5d5Øg36M/gg365P(5MP(5~N6RË7`RAn&5?=/<noMP45-Ê*M7tAn5)T]MN6M:neR*AR< TVgjR$g35 «%SoN w#TW=/<gjD c3S&=3~$S&nonCtPR6 *M- Anol%P5:7rMSoNrMk<ANS&)<5 =-R6<AN?gj5P(5/Ê*M:7rtCne51 2_<g&gSoNrMN`MttAno5 M ;Ml`7rMl`ÐA55t8TlA7r75LgPl$M/$Ml'1 xVg3MN Ð
(40) YNN5 M/<AtA5cMN;[ØR ASvNXZSn&nMP]RPqSo7tPR6dASoNg365%7`MN)<!T(=P(StgWRg3S&T]MP#gSo=n5%MN;8R*PVg35 +P#<Shgj<nA;*S+T=/< TLT(SeR*N1 v (- ! -v( ?1 9WnoS&5noDV9 1 U¤1 Vµ¯Sn&5N6Das 1 ^81¿v¹Àȹ·ºA¹¶cÁv¼/¿eÀÏ· aÀ '¾ÍAÁº
(41) q·¶ ]·»Í ¼ q0ÈR*3N6D_µ¯S&n5l sARNCTD x+pr2 1pr5/$J#zR*Pj Ð Dt 1+yCB1 > 1?Á+ÂÁ 1)t1KBA1 I'1UV< N6Jb%tgR*N6D6^1fÌ A¹ ¶ »º "!$##%-DåE6D*H CK6H '1 H 1^`MP+gD^r1LÌ $ A¹ ¶ » º !$##%& åEGuI> uIH 1 KA1 2qR*nonSvN'TD6X 1)0-1/'Ì % A¹( ¶ »º $!$##% &!åE)GWLH'B?H fH'BKA1 . K.
(42) u'1^`MN6=RA=ÐAD6[\1:ä1fÌ$ A¹¶( »º $!$### &!ååÈGyCBByy> 1 '1^~<A3655lD01 9Ø1 ÍA·À '¾ÍAÁ&º A¹¶cÁv¼/¿eÀ 1I 94;C1^$MPt5P [ØR`Dpr5/$J#zR*PjÐD Dt'1 HAyI'1 BA1µ¯5PjN5P(DY` 1 a¹À %?DÙÙDBB JB yCB1 y'1µ¯5PjN5P(DY` 1 a¹À % !ADÙFADL>VJI@C1 @'1^`5PjP(5/PjRAD's 1 ?bTR*N6D6X 1 Y`1/Ì % A¹( ¶ » º
(43) &'åÜGW@uCK@uuC1 ?1 MPN5/ggjD c1 U¤1 ?b`=3)g7rMND 1 Y`1 ÍA·À A¹( ¶ DÅ?EÄ Å ÆD>Au H'1 L> 1[ M-;MNRdAS D6ä1ä81 ?[alA=3n5/rTÐAMkb1 ?ä]<AP(MN6D6X 1)xL1 ?µ¯MP ?M#gjSTD c1 ?ä%P( M jÐAR6dAS D?p
(44) 1As 1 a<AP(5(S-D ä1:X 1 ]·¸ %A¹ ÀL·ÍD !$##DÜAÕD>VB IJ>Vy> 1 I'1'µ¯5SoDVz1 zr1 Î_SoNMN?gjD c1 ä$5=no5P=D½0-1×J W1 cMN
(45) XZ5-5PfTfT=365D X 1 ä$Mn&5-D½0- 1 º?¿e¾ _À ¼¿ D & ]ÙÕD½L> @JL> H'1. u.
(46)
Documents relatifs
To test whether the vesicular pool of Atat1 promotes the acetyl- ation of -tubulin in MTs, we isolated subcellular fractions from newborn mouse cortices and then assessed
Néanmoins, la dualité des acides (Lewis et Bronsted) est un système dispendieux, dont le recyclage est une opération complexe et par conséquent difficilement applicable à
Cette mutation familiale du gène MME est une substitution d’une base guanine par une base adenine sur le chromosome 3q25.2, ce qui induit un remplacement d’un acide aminé cystéine
En ouvrant cette page avec Netscape composer, vous verrez que le cadre prévu pour accueillir le panoramique a une taille déterminée, choisie par les concepteurs des hyperpaysages
Chaque séance durera deux heures, mais dans la seconde, seule la première heure sera consacrée à l'expérimentation décrite ici ; durant la seconde, les élèves travailleront sur
A time-varying respiratory elastance model is developed with a negative elastic component (E demand ), to describe the driving pressure generated during a patient initiated
The aim of this study was to assess, in three experimental fields representative of the various topoclimatological zones of Luxembourg, the impact of timing of fungicide
Attention to a relation ontology [...] refocuses security discourses to better reflect and appreciate three forms of interconnection that are not sufficiently attended to
