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The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer

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Academic year: 2021

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FIGURE 1 | Expression of FLRT3/LPHN/Tim-3/galectin-9 pathway components and activities of PLC/PKCα and mTOR pathways in primary human breast tumors.
FIGURE 2 | Expression, interaction, and co-localization of Tim-3 and galectin-9 in primary human breast tumors
FIGURE 4 | FLRT3 induces translocation of galectin-9 onto the surface of MCF-7 breast cancer cells
FIGURE 5 | Galectin-9 protects MCF-7 cells against T cell-dependent cytotoxic immune attack
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