« Sunshine on Opinion Leaders » : étude rétrospective des liens d’intérêt financiers entre les leaders d’opinion médicaux et l’industrie pharmaceutique en France

Texte intégral

(1)“ Sunshine on Opinion Leaders ” : étude rétrospective des liens d’intérêt financiers entre les leaders d’opinion médicaux et l’industrie pharmaceutique en France Marie Clinckemaillie. To cite this version: Marie Clinckemaillie. “ Sunshine on Opinion Leaders ” : étude rétrospective des liens d’intérêt financiers entre les leaders d’opinion médicaux et l’industrie pharmaceutique en France. Médecine humaine et pathologie. 2020. �dumas-03117829�. HAL Id: dumas-03117829 https://dumas.ccsd.cnrs.fr/dumas-03117829 Submitted on 21 Jan 2021. HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés..

(2) . "!! # !

(3) . .

(4) 3<4&/5<&&54065&/6&16#-*26&.&/5-&/07&.#3& ;-""$6-5<%&<%&$*/&%&*$&1"3 "3*& <&-&."34

(5)

(6) ; . ")+,)+!0*$ '+,))"& . %)*,#,). )/*"&+$)'**,) *$ %)*$)'**,) -" %)*%$)'**,) )" "++ %)*$)'**,)

(7) $')"&.

(8) . . . .

(9) . . #*+*&*#!&&+*,)*(+%) /$,$+00#&# ")! %*'% ")!&. . +" % +%"!$( %%

(10) !'(!'&

(11) "!. . %+ &&"!#%"' #(&. % ##. . DCH:GK6I:JG9:A67>7A>DI=VFJ:. &B:&,%%6C>VA:. . >G:8IG>8:69B>C>HIG6I>K:9:HH:GK>8:H. &B:%%"H67:AA:. . DN:CH!DCDG6>G:H. & +&)%)6IG>8@ & '!"&(%6C>:A . . .

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

(13) +U6C>B6I>DC&U9>86A:

(14) 6C8UGDAD<>:_ UCUI>FJ:

(15) =>GJG<>:(GI=DEU9>FJ::I-G6JB6IDAD<>FJ:

(16)

(17) >DE=NH>FJ::I&U9:8>C:'J8AU6>G:

(18) )=6GB68DAD<>:A>C>FJ:

(19) 'UE=GDAD<>:

(20) >DAD<>::AAJA6>G:

(21) =>GJG<>:><:HI>K:

(22) =>GJG<>:/6H8JA6>G:

(23) 'JIG>I>DC

(24) C6IDB>::INIDAD<>:)6I=DAD<>FJ:H

(25) C:HI=UH>DAD<>::I+U6C>B6I>DC=>GJG<>86A:

(26) :GB6ID /UCUGUDAD<>:

(27)

(28) =>GJG<>:K6H8JA6>G:BU9:8>C:K6H8JA6>G:

(29) )C:JBDAD<>:

(30) )6G6H>IDAD<>::I&N8DAD<>:

(31) C6IDB>::INIDAD<>:)6I=DAD<>FJ:H

(32) 6C8UGDAD<>:+69>DI=UG6E>:

(33) =>GJG<>:-=DG68>FJ::I6G9>DK6H8JA6>G:

(34) +69>DAD<>::I"B6<:G>:&U9>86A:

(35) ':JGD8=>GJG<>:

(36) UCUI>FJ:

(37) QE>9UB>DAD<>:Q8DCDB>:9:A6,6CIU:I)GUK:CI>DC

(38) &U9:8>C:%U<6A::IGD>I9:A6,6CIU

(39) C:HI=UH>::I+U6C>B6I>DC=>GJG<>86A:

(40) )HN8=>6IG>:9`9JAI:H

(41) 'JIG>I>DC

(42) !UE6ID 6HIGD :CIUGDAD<>:

(43) . . .

(44) . . )+(,,.+,)+&"+%,, &B: & & & &B: & & & & & & & & & & & & & &B: & & & & & . ,$'32 "--+ADG:C8: ++' +BB6CJ:A Q++QI>:CC: (' "'C9GU +."%/UGDC>FJ: ,-"%%(%6JG:CI !/%%"+)6IG>8@ )+--":GC6C9 +++"QB>A: +++(#:6C &6G8 ('-"':CNH .Q+"'(A>K>:G !''(.' %/"#:6C &>8=:A #')-",-A>MVC: %/+.-#68FJ:H %('#('&>8=:A ),,+('-=>:GGN )"!-=>:GGN +2'.DB>C>FJ: +(,'-!%QG>8 +(.1=G>HI>6C ,-"'")6H86A -!(&,)>:GG: -+(#'"=G>HIDE=: . . . . )U9DEHN8=>6IG>:

(45) NCU8DAD<>:(7HIUIG>FJ:

(46) )U9>6IG>:

(47) NCU8DAD<>: (7HIUIG>FJ:

(48) +=JB6IDAD<>:

(49)

(50) ( + %

(51) +69>DAD<>::I"B6<:G>:&U9>86A:

(52) C6IDB>: =>GJG<>:(GI=DEU9>FJ:

(53) 6G9>DAD<>:

(54) 6C8UGDAD<>:+69>DI=UG6E>:

(55) ':JGD8=>GJG<>:

(56) &U9 "C UG>6IG>:

(57) 6C8UGDAD<>:+69>DI=UG6E>:

(58) =>GJG<>:K6H8JA6>G:

(59) &U9:8>C:9`JG<:C8:

(60) ':JGD8=>GJG<>:

(61) :GB6ID /UCUGUDAD<>:

(62)

(63) 6HIGD :CIUGDAD<>:

(64) !UB6IDAD<>:

(65) &U9:8>C:"CI:GC:

(66) G=JB6IDAD<>:

(67)

(68) >DHI6I>HI>FJ:H:I"C;DGB6I>FJ:&U9>86A:

(69) ':JGDAD<>:

(70) =>GJG<>:(GI=DEU9>FJ::I-G6JB6IDAD<>FJ:

(71)

(72) .

(73) . . )+(,,.+,.1"&%,, &B: & & &B: &B: & & & & & & &B: & &B: & & & &B: & & &B: &B: & & & & & &B: &B:. %.''"/UGDC>FJ: '-2+D9DAE=: !(+')=>A>EE: "%%",IUE=6C>: ''0+-!,NAK>: '"3+"BB6CJ:A '("-&>8=:A +-!-#:6C )=>A>EE: (3A:M6C9G: +.#:6C +(',+'>8DA6H .+% /''(,6CCN !/%"+'>8DA6H !"'--" >JA>6 %.3.-=DB6H %%&('"#:6C %(--#UGYB: ,-+' )(&+,=G>HI:AA: /+ J>AA6JB: (.+'"+#:6C )6JA "(+'' (/6AUG>: "(/''"'" !&"%>H6 "''%%"CIDC>D "%"&6G>JH (+'#:6C =G>HIDE=: +(!+%"!)>:GG: +."&2+6NBDC9 ,('",67G>C6 ,"-3 )(%,$"6G76G6. &U9:8>C:%U<6A::IGD>I9:A6,6CIU

(74) 6HIGD :CIUGDAD<>:

(75) NIDAD<>::I!>HIDAD<>:

(76) (E=I6ABDAD<>:

(77) UCUI>FJ:

(78) =>GJG<>: UCUG6A:

(79) )HN8=>6IG>:

(80) =>GJG<>:-=DG68>FJ:

(81) (+% 6C8UGDAD<>:

(82) =>GJG<>:"C;6CI>A:

(83) C6IDB>:=>GJG<>:(GI=DEU9>FJ::I-G6JB6IDAD<>FJ:

(84) C6IDB>::INIDAD<>:E6I=DAD<>FJ:H

(85) C9D8G>CDAD<>:>67VI::I&6A69>:H&UI67DA>FJ:H

(86) >D8=>B>: >DAD<>:&DAU8JA6>G:

(87) !UB6IDAD<>:

(88) GU6C>B6I>DCBU9>86A:

(89) NCU8DAD<>: D7HIUIG>FJ:

(90) )6G6H>IDAD<>::IBN8DAD<>:

(91) 'UE=GDAD<>:

(92) -=UG6E:JI>FJ:

(93) 68IUG>DAD<>: />GDAD<>:

(94) )U9>6IG>:

(95) =>GJG<>:><:HI>K:


(97) C:HI=UH>DAD<>: GU6C>B6I>DC&U9:8>C:9JG<:C8:

(98) )U9>6IG>:

(99) 68IUG>DAD<>: K>GDAD<>:

(100) ':JGDAD<>:

(101) "BBJCDAD<>:

(102) . . . .

(103) . . &"-+,('Q+',,.'"/+,"-Q, )+-""',!(,)"-%"+, & &B: & &B: & & & & &B: & &B: &B: & &B: & &B: & &B: & & & & &B: & & . &+(,--"6B>:C +'+ )(&"+ =>HA6>C: &.3+(A>K>:G ('-'-" %")+'"#JA>: ( %"(A6>C (2'#UGYB: (,,-=>:GGN ++(+D9DAE=: !"'.%-=6GADII: !.&+-(A>K>:G %&2G><>II: %(' &"+AD9>: %(--+DB6>C & '"Q&6G>: 'DXAA: &,,%(.6B>:C &(+")6B:A6 &('-."!:CG> &.,,( %,,%%,6C9G6 'a&"&DJG69 ,/(%%%"=6GA:H ,*.+67>:C -,-#:6C -!.&&%+,JH6CC: -(.%(')>:GG: -+'CID>C:. NIDAD<>::I!>HIDAD<>:

(104) "BBJCDAD<>:

(105) =>GJG<>:)A6HI>FJ:

(106)

(107) &U9:8>C:9JG<:C8:

(108) 68IUG>DAD<>: />GDAD<>:

(109) +69>DI=UG6E>:

(110) 68IUG>DAD<>: />GDAD<>: !N<>VC:

(111) )=6GB68DAD<>:DC96B:CI6A:

(112) >D8=>B>::I7>DAD<>:BDAU8JA6>G:

(113) >DE=NH>FJ::I&U9:8>C:'J8AU6>G:

(114) 68IUG>DAD<>: K>GDAD<>:

(115) NIDAD<>::I!>HIDAD<>:

(116) 68IUG>DAD<>: K>GDAD<>:!N<>VC:=DHE>I6A>VG:

(117) )=NH>DAD<>:

(118) =>GJG<>:/>H8UG6A:

(119) 6G9>DAD<>:

(120) :GB6IDAD<>:

(121)


(123) >D8=>B>::I>DAD<>:BDAU8JA6>G:

(124) =>GJG<>:B6M>AAD ;68>6A::IHIDB6IDAD<>:

(125) 6G9>DAD<>:

(126) QE>9UB>DAD<>:Q8DCDB>:9:A6,6CIU:I)GUK:CI>DC

(127) )U9DEHN8=>6IG>:

(128) !UB6IDAD<>::I-G6CH;JH>DC

(129) )U9>6IG>:

(130) . . .

(131) . . )+(,,.+,.'"/+,"-Q, &U9:8>C: UCUG6A:

(132) . & +&('6K>9. &"-+('Q+',,.'"/+,"-Q, &B:. +(,JG>6C:. (GI=DE=DC>:. )+(,,.+, +Q Q, C<A6>H. &B: %'"+:7:886. )+-""'!(,)"-%"+ .'"/+,"-"+ & & . .+'&6II=>:J ,"+CID>C:. .GDAD<>:

(133) 'UE=GDAD<>:

(134) . )+(,,.+,,,("Q, & +(' >AA:H &B: &(''"+G><>II:. &U9:8>C: UCUG6A:

(135) &U9:8>C: UCUG6A:

(136) . &"-+,('Q+',,,("Q, &B: & & . ,-UA>C: ,)+"'"67G>8: !( .'>8DA6H. &U9:8>C: UCUG6A:

(137) &U9:8>C: UCUG6A:

(138) &U9:8>C: UCUG6A:

(139) . . DCHI>IJI>DC9J?JGN:CFJ6A>IU9:VB:B:B7G:. )GD;:HH:JGH!DCDG6>G:H & &"%#:6C & %+-"'"&6G8 & %,6C>:A & --&>8=:A & %"/GJCD & (*.-)6IG>8: & (.+ ('C9GU & (.--Q)6IG>8@ & +.'-('#:6C 'DXA &B:.,,"+G6CTD>H: & &(.,#:6C )>:GG: & '"/-:GIG6C9 & ,,.-(#>AA E6IG>8: & !-%&6G8:A. . & Q++#:6C )>:GG: & "%"')>:GG: & "%%-#:6C 2K:H & +%%"+)6IG>8@ & +"&.DB>C>FJ: & !(%" +)=>A>EE: & #(.+'#68FJ:H & %&+-#:6C A6J9: & %3.',$"&>8=:A & %/+#:6C A6J9: & %"!(.12K:H &B:%+-('A>H67:I= & &+"'"+D<:G & &,,2+:CU.

(140) . . & (.,,&'-A6>C &B:+',,DB>C>FJ: & +(.+- JN & %%&('")>:GG: & %&('-#:6C & &+G6CTD>H & ,'.%%A6J9: & (%","A6J9: &B:.%%+ 3" %+%>6C6 & '"!%)6IG>8@ & .3"-#:6C 67G>:A & +'(A6>C & +2!-)>:GG: & ,-.)>:GG:. & &--"&6I=>:J & &(."%#:6C &B:&2*.%&6GI>C: & (+-(''#:6C )6JA & )+"' .2DB>C>FJ: & ,'-"'"#DH:E= & ,.-+('#:6C6EI>HI: & ,!'"+&6JG>8: & -!2,,CID>C: & -(.(%#68FJ:H & -+'>C=$=>:B & /'(+ !' BB6CJ:A. & . !DCDG6>G:H & +'(%#68FJ:H & ,-+",:GC6G9 & '(%"%#DHU &AA:!"!&'"'+DH: &6G>: &B:('3.&>8=VA: & &"%"(33"+DBUD & +'$')=>A>EE: & ,-.&6G8:A. & "."%%"#:6C & & 'Q#68FJ:H &B:&&+''69>C: & &' .%+6NBDC9 & )!"%"))6IG>8@ & )("+Q#:6C A6J9: &B:+(.+&6G>: A6>G:. )+(,,.+,('/'-"(''Q,%`.'"/+,"-Q & & & &B: & & &B: & & & & . . . +-+'G6CTD>H +($+)6IG>8: !/%%"+6C>:A (.+'"+ &!(.,&6CJ:AA6 #&(.)6IG>8@ %(.&6I=>:J '. :C:K>VK: ("' J>AA6JB: )2+GU9UG>8 )"+:GIG6C9 *.+'-#:6C G6CTD>H. &U9:8>C:"CI:GC: &U9:8>C:"CI:GC:(EI>DC UG>6IG>: .GDAD<>: &U9:8>C:)=NH>FJ::I+U696EI6I>DC DDG9>C6I>DCEGUAVK:B:CIH9`DG<6C:H <NCU8DAD<>: D7HIUIG>FJ: .GD <NCU8DAD<>: =>GJG<>:B6M>AD ;68>6A: (C8D !UB6IDAD<>: )HN8=>6IG>: ,6CIU)J7A>FJ:.

(141) .

(142) . 2%'&()/*"&+,). $A@E;7GD>7'DA87EE7GD*F355;@; -AGE?783;F7E>`:A@@7GD67BDPE;67D57<GDK $7D5;6`3HA;DBD;E>7F7?BE676;E5GF7D?A@BDA<7F7F@AGDD;D?3DP8>7J;A@ -AFD7<G97?7@FNG@7H3>7GD5A@E;6PD34>7N?7EK7GJ *AK7L3EEGDP67?A@BDA8A@6D7EB75F7F67FAGF7?3D75A@@3;EE3@57 2%'&#, $A@E;7GD>7'DA87EE7GD3D?A@ -AGE?783;F7E>`:A@@7GD67<G97D57FD3H3;> "7E3;EHAFD77@9397?7@F63@E>3FD3@E?;EE;A@67HAFD76;E5;B>;@77F63@E>3CG3>;FP67>3 D75:7D5:77@?P675;@79P@PD3>7 "`7EBQD7CG757FD3H3;>E7D36;9@767E7@E7;9@7?7@FE6G)$ )757H7LFAGE?7ED7?7D5;7?7@FE7F>7FP?A;9@39767FAGF7?35A@E;6PD3F;A@ 2%'&#, $363?7>7'DA87EE7GD$A@@;7D "7HAGED7?7D5;7E;@5QD7?7@F6`3HA;D3557BFP67<G97D?A@FD3H3;> -AGECG;RF7E7@939P763@E>`7@E7;9@7?7@F7F>3D75:7D5:77@?P675;@79P@PD3>7 "`7EBQD7HAGE83;D7:A@@7GD "7HAGEFP?A;9@7?3B>GE9D3@67D75A@@3;EE3@57 . .

(143) . . 2%'&#, $A@E;7GD>7'DA87EE7GD%3G67F "7F7D7?7D5;7BAGDFA@7@F:AGE;3E?7F36;EBA@;4;>;FPFA@7@9397?7@F7FFA@7JB7DF;E7 +D3H3;>>7D3H75FA;3PFPG@HD3;B>3;E;D7FD;5:76`7@E7;9@7?7@FE #7EPFG6;3@FE7F5:7D5:7GDE4D7FA@EA@F473G5AGB675:3@5767F`3HA;D *A;E3EEGDP67?A@BDA8A@6D7EB75F7F67?3E;@5QD79D3F;FG67 2%'&")+,)+!0* $A@E;7GD>76A5F7GD3D43DAGJ $7D5;NFA;E3@ECG;57FD3H3;>@`3GD3;F<3?3;EPFPBAEE;4>7 $7D5;6`3HA;D5DG7@?A;6`3HA;DPFPE;6;EBA@;4>75A?BDP:7@E;87F?AF;H3@F +G7EB3EE;A@@P7FB3EE;A@@3@F "7EG;E8;QD77F5:3@57GE76`3HA;DFD3H3;>>P3H75FA; . .

(144) . . [D@3G6FG@`3GD3E<3?3;E3GF3@FBDAGHPF7E9D3@67ECG3>;FPECG757FF73@@P7<7F`3;?7 BAGD57>37FBAGDF3@F6`3GFD7E5:AE7E $7D5;6`RFD7FA;7F6`RFD7FAG<AGDE>NBAGD?A; [?7EB3D7@FENCG;<76A;EFAGF7FCG7<7@7BAGDD3;E<3?3;E3EE7LD7?7D5;7DBAGDHAFD7 EAGF;7@E;EA>;677FHAFD73?AGDE3@E83;>>7 [$3F:;>677F';7DD7BAGDHAFD73?AGD7FHAFD7:G?AGDB>GE6AGF7GJ "7EG;E8;QD767 HAGE3HA;DN?7E5TFPE [?39D3@6 ?QD7BAGDFA@3?AGD7FF34A@FP;@8;@;E7FB3D57CG7FGB7@E7EN?A;FAGE >7E<AGDE "7F76P6;757FD3H3;> [?7E5AB;@7E67FAG<AGDE'3G>;@7$3D93GJ$3@A@$3F:AGEF7>>7HAFD73?;F;P H3GF67>ÀD7F5A?BF7P@AD?P?7@FBAGD?A; [?7E5AB3;@E6G%AD6@: >3;D73DA>;57"G>;7:>AP/H7E';7DD7,9ABAGD @AEBD7?;7DEB3E5A?B>;57E7F<AK7GJ63@E>3H;7PFG6;3@F7?;P@A;E77FHAFD73?;F;P E;BDP5;7GE7BAGDFD3H7DE7D>`7JF7D@3F [ ?7E 5AB3;@E 6G *G6 "G>;7 $3D;A@ >A @@3 D76 BAGD >3 5:3@57 6`3HA;D PFP 355A?B39@P7B3DHAGE63@E>3H;76`;@F7D@77FBAGD>347>>73H7@FGD75ADE7CG7HAGE ?`3H7LB7D?;E67H;HD7 GJBD3F;5;7@E:AEB;F3>;7DE7F?3SFD7E67EF397;@EB;D3@FECG7<`3;5DA;EPEGD>3DAGF767 ?38AD?3F;A@ "7 HAG6D3;E 7@8;@ D7?7D5;7D >7J3@6D7 BAGD EA@ 3;67 7EE7@F;7>>7 7F 5A@E;6PD34>7 N >3 DP3>;E3F;A@6757FD3H3;> 7>33PFPG@75:3@577FG@B>3;E;D675A>>34AD7D3H75FA; . .

(145) . . . #+&$5*' MFG6;7D>3@3FGD7>7HA>G?77F>PHA>GF;A@67ED7>3F;A@E8;@3@5;QD7E7@FD7>7E?P675;@E>7367DE 6AB;@;A@ 7F @A@ >7367DE 6ÀB;@;A@ 7F >`;@6GEFD;7 B:3D?357GF;CG7 7F 67 BDA6G;FE 67 E3@FP 7@ D3@57 . :1&%><56%& MFG67DPFDAEB75F;H77F67E5D;BF;H7 . "35*$*1"/54 +AGE>7E?P675;@E7J7DO3@F7@D3@573H75G@8A5GEEGD>7E>7367DE6ÀB;@;A@#&6P8;@;E 5A??7 >7E ?7?4D7E 6G 4GD73G D7EFD7;@F 67E EA5;PFPE E3H3@F7E 3K3@F BG4>;P 67E 9G;67E 67 BD3F;CG75>;@;CG77@

(146) AG

(147) 7EEA5;PFPEA@FPFP;67@F;8;P7EB3D>7D75AGB7?7@F67 6;88PD7@FE53F3>A9G7E63EEA5;3F;A@EBDA87EE;A@@7>>7E8D3@O3;E7E . 3*/$*1"-&4.&463&4 #7@A?4D77F>7?A@F3@FFAF3>67E3H3@F397ED7OGEB3DFAGE>7E?P675;@E7FB3D>7E#&;67@F;8;PE 3@@P7B3D3@@P767BG;E

(148) #7@A?4D77F>7?A@F3@F67E53FP9AD;7EEGBB>P?7@F3;D7E67 >;7@E6;EBA@;4>7E67BG;E

(149) 57EF N 6;D7>7EDP?G@PD3F;A@E7F>7E5A@H7@F;A@E7F>7@A?4D7 675A@H7@F;A@EE3@E?A@F3@F6P5>3DP6P5D;F7EBAGDFAGE>7E?P675;@E7F>7E#&3@@P7B3D3@@P7 67BG;E

(150) . <46-5"54 #7E?P675;@EA@FD7OG ?a? ?V6`3H3@F397E6P5>3DPE67

(151) N

(152) 67E #&3H3;7@F67E3H3@F397E6P5>3DPE #7E#&;67@F;8;PED7BDPE7@F3;7@F

(153) 67E?P675;@E 7@D3@57?3;EA@FD7OG 6G?A@F3@FFAF3>67E3H3@F397EEA;F ?a ? ?VAG

(154)

(155) aB3DB7DEA@@77FB3D3@ #7E?P675;@EA@FD7OG ?a ?7F ?V7@5A@H7@F;A@E6P5>3DP7E67

(156) N

(157) ?;>>;A@ 67 5A@H7@F;A@E A@F 7G >7GD ?A@F3@F 535:P #7E #& A@F D7OG

(158) 67E 5A@H7@F;A@E7@@A?4D77F67>3H3>7GD67E5A@H7@F;A@EEA;F ?a??VAG

(159)

(160) aB3DB7DEA@@7B3D3@

(161)

(162)

(163)

(164) V #7E?P675;@EA@FD7OG ?a ?7F ?67DP?G@PD3F;A@E6P5>3DP7E67

(165) N

(166) #7E#&;67@F;8;PEA@FD7OG67>3H3>7GDFAF3>767EDP?G@PD3F;A@E67E?P675;@EEA;F ?a??VAG

(167)

(168) aB3DB7DEA@@77FB3D3@

(169)

(170)

(171)

(172) V 'D7ECG7FAGF7E>7EEA5;PFPEE3H3@F7E5A?BF3;7@F63@E>7GD4GD73GD7EFD7;@F3G?A;@EG@ #&3K3@F3G?A;@EG@>;7@8;@3@5;7D . 0/$-64*0/ #7E>;7@E6`;@FPDRF7@FD7>7E#&7F>;@6GEFD;77@D3@57EA@F?3<7GDE;>EEA@F473G5AGBB>GE ;?BADF3@FECG`3H75>7EBD3F;5;7@E@A@#& #3BD;@5;B3>7>;?;F76757FF7PFG67F;7@FN>3CG3>;FP 67E ;@8AD?3F;A@E 8AGD@;7E 63@E >3 43E7 67 6A@@P7E 8D3@O3;E7 B>GE 67E FDA;E CG3DFE 67E 5A@H7@F;A@EA@F>7GD?A@F3@F535:P?3>9DP>A4>;93F;A@67>;@6;CG7D #7?A@F3@F67EB3;7?7@FE EAG>QH7 67E CG7EF;A@E EGD >3 @P57EE3;D7 ;@6PB7@63@57 67 57GJ CG; DP6;97@F >7E 9G;67E 67 BD3F;CG7E5>;@;CG7E7F3<AGF767>3>P9;F;?;FP3GJ3BB7>ENG@7DP8AD?767>3DP9>7?7@F3F;A@ @D79;EFD7?7@F&B7@*5;7@57D3?7IAD=AE8 ;A 3<:FJ $AFE5>PE5A@8>;F6`;@FPDRF>;7@E8;@3@5;7DE>7367DE:;B?P675;@E;@6GEFD;7B:3D?357GF;CG7 . .

(173) . . " #;EF767E7@E7;9@3@FEZZZZZZZZZZZZZZZZZZZZZZZZZZZ. Z )7?7D5;7?7@FEZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ.

(174) )PEG?PZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ. Z +34>767E?3F;QD7EZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ !@FDA6G5F;A@ZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ. $PF:A67ZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ !67@F;8;53F;A@67EEA5;PFPEE3H3@F7EZZZZZZZZZZZZZZZZZZZZ !67@F;8;53F;A@67E>7367DE6À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`PFG67ZZZZZZZZZZZZZZZZZZZZZZZZ (G7EF;A@ED7EF3@FAGH7DF7E7FD75:7D5:7E8GFGD7EZZZZZZZZZZZZZZZ )P8PD7@57EZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZZ Z .

(175) . .

(176)

(177) #;@FPDRFBAGD>7ED7>3F;A@E7@FD7>;@6GEFD;7B:3D?357GF;CG77F>7EBDA87EE;A@@7>E67>3E3@FP@7 57EE7675DASFD7 G5AGDE67>367D@;QD76P57@@;767@A?4D7GJB3KEA@F>P9;8PDP7F;?BAEP>3 FD3@EB3D7@5763@E>7ED7>3F;A@E7@FD7>;@6GEFD;77F>7E?P675;@E [>;@EF3D67EMF3FE ,@;E3H75 >3>A;':KE;5;3@'3K?7@FE*G@E:;@75F>3D3@5735DPP7@

(178) >343E7676A@@P7EBG4>;CG7 43E7+D3@EB3D7@57*3@FPFD3@EB3D7@57 E3@FP 9AGH 8D #7E;@6GEFD;7EB:3D?357GF;CG7E7F 676;EBAE;F;8E?P6;53GJEA@FF7@G7EB3D>3>A;676P5>3D7D63@E>343E7676A@@P7E>3H3>7GD7@ @3FGD7AG7@DP?G@PD3F;A@CG7>>7EFD3@E8QD7@F3GJBDA87EE;A@@7>E7FAD93@;E?7E67E3@FP7@ D3@57 7E >;7@E 6`;@FPDRF B7GH7@F 38875F7D FAGE >7E 3EB75FE 67 >`35F;H;FP ?P6;53>7 67 >3 D75:7D5:7 N >3 BD3F;CG7 5>;@;CG7 #7E 7EE3;E 5>;@;CG7E 7F >7E ?PF3 3@3>KE7E 5A??3@6;FPE B3D >;@6GEFD;7B:3D?357GF;CG7EA@FB>GEEGE57BF;4>7E675A@5>GD7N>788;535;FP67E?P6;53?7@FE #7E>;7@EEA@F3EEA5;PEN67EBD7E5D;BF;A@EB>GE5AUF7GE7EB>GE8DPCG7@F7E7F67?A;@6D7CG3>;FP . #7ED75A??3@63F;A@EBAGD>3BD3F;CG75>;@;CG7CG;6P8;@;EE7@F>7E5D;FQD7E676;39@AEF;57F >7FD3;F7?7@F67E?3>36;7EEA@FP93>7?7@FEAGE;@8>G7@57BG;ECG7>7GDE3GF7GDEA@F67E>;7@E 3H75>;@6GEFD;7

(179) #7E D75A??3@63F;A@E BAGD >3 BD3F;CG7 5>;@;CG7 EA@F DP6;9P7E B3D 67E ?P675;@E 7JB7DFE >7E >7367DE6AB;@;A@#& #7F7D?7#&3PFP;@H7@FP63@E>7E3@@P7E

(180) B3D>7F:PAD;5;7@67>3 5A??G@;53F;A@ '3G> #3L3DE87>6 7F EA@ PCG;B7 63@E >7 536D7 6PFG67E EGD >;@8>G7@57 CG; A@F 6P?A@FDPCG7>7EB7DEA@@7EE783;E3;7@FG@7AB;@;A@63H3@F397N53GE76757DF3;@E;@6;H;6GE67 >7GDEDPE73GJ AG>7367DE6AB;@;A@ CGN53GE767E?P6;3EAG67>3BG4>;5;FP '>GEF3D6>7 9DAGB767#3L3DE87>63FD3H3;>>PEGD>7E?P675;@E7F3?A@FDPCG7>;@8>G7@5767EDPE73GJEA5;3GJ 67E ?P675;@E 7EF ?3<7GD7 BAGD >7GD 83;D7 36ABF7D G@ @AGH73G ?P6;53?7@F G<AGD6:G; 5`7EFG@F7D?7?3D=7F;@9 3@E>7E75F7GD67>3E3@FP>7?AF#&6PE;9@7>7E?P675;@ECG; ;@8>G7@57@F>3BD3F;CG7?P6;53>767>7GDEB3;DEK5A?BD;E>7E:34;FG67E67BD7E5D;BF;A@ #7E 7@FD7BD;E7EB:3D?357GF;CG7E7@9397@F67E>7367DE6AB;@;A@N6;88PD7@FEEF367E6GBDA57EEGE67 6PH7>ABB7?7@F67E?P6;53?7@FE67E7EE3;E5>;@;CG7E<GECG`N>3BDA?AF;A@ #7E#&EA@F67E?P675;@EAG67E5:7D5:7GDED7EB75FPE63@E>7GD6A?3;@77FD75A@@GEBAGD>7GD FD3H3;> !>E6PF;7@@7@FG@F;FD7G@;H7DE;F3;D77F AG8A@FB3DF;76G@5A?;FP67JB7DFE !>E;@8>G7@57@F >7GDE5A>>Q9G7EN9D3@67P5:7>>7B3D>7GDEBG4>;53F;A@E>7GDE;@F7DH7@F;A@E>ADE675A@9DQE7F>7E 9G;67E67BD3F;CG75>;@;CG7CG;>E5A@FD;4G7@FNDP6;97D A??7>7E#&EA@FB3D6P8;@;F;A@ G@B7F;F9DAGB7;>EB7GH7@FRFD7G@75;4>7BD;H;>P9;P7N67E8;@E5A??7D5;3>7E 7EPFG67EFDQE DP57@F7E A@F 6P5D;F 67E >;7@E 6`;@FPDRF ?3<7GDE 7@FD7 >7E 6;D;973@FE 67E EA5;PFPE E3H3@F7E 67 ?P675;@77F>;@6GEFD;7B:3D?357GF;CG77@?PD;CG76G%AD6 @D3@5757E>;7@E@A@F <3?3;EPFPPFG6;PE 3@E57FF7PFG67@AGE3HA@E6P5D;F>3@3FGD77F>PHA>GF;A@67E3H3@F397E67E5A@H7@F;A@E7F 67EDP?G@PD3F;A@EB7DOGEB3D>7E?P675;@E#&7F@A@ #&7@GF;>;E3@F>7E6A@@P7E67>343E7 +D3@EB3D7@57 *3@FP %AGE 3HA@E P93>7?7@F D79DAGBP >7E 3H3@F397E 5A@H7@F;A@E 7F DP?G@PD3F;A@EB7DOGEB3D57E#&BAGD5:3CG7EA5;PFPE3H3@F7N>3CG7>>7;>E3BB3DF;7@@7@F .

(181) . .

(182) A@8AD?P?7@FN@AFD7BDAFA5A>77@D79;EFDP>73HD;>

(183)

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

(185) AG

(186) 7@GF;>;E3@FAA9>7E5:A>3D>34;4>;AF:QCG7?P6;53>7G@;H7DE;F3;D76G ,6G $3@E7F>7?AF7GD67D75:7D5:7!*$BAGD>7ED75A??3@63F;A@EBAGD>3BD3F;CG75>;@;CG7 . %&/5*'*$"5*0/%&4&"%&34%>1*/*0/ @ GF;>;E3@F >7 E;F7 I74 67 5:3CG7 EA5;PFP E3H3@F7 G@ 3GF7GD $ 3 ;67@F;8;P 7@FD7 A5FA4D7

(187) 7F?3;

(188)

(189) >7E?7?4D7E67>7GD4GD73GD7EFD7;@F #7E#&A@FPFP6P8;@;E5A??7?7?4D7E6G4GD73G676;D75F;A@67>3EEA5;3F;A@57EF N 6;D7BDPE;67@FH;57 BDPE;67@FE75DPF3;D7H;57 E75DPF3;D7FDPEAD;7DH;57 FDPEAD;7D?3;EB3E67E EAGE 5A?;FPE %AGE3HA@E;67@F;8;P>7E#&B3D>7GD@A?>7GDEBP5;3>;FP?P6;53>77F>7GDH;>>7 67BD3F;CG7 *;57E;@8AD?3F;A@E@`PF3;7@FEGD>7E;F7I7467>3EA5;PFPE3H3@F7$>7E35:7D5:P EGD >7 ?AF7GD 67 D75:7D5:7 AA9>7 7@ GF;>;E3@F >7GD @A? 7F >3 EBP5;3>;FP ?P6;53>7 67 >`3EEA5;3F;A@ #7E6;H7D97@57E7F>7E;@57DF;FG67E63@E>;67@F;8;53F;A@67ED75A??3@63F;A@E67 BD3F;CG75>;@;CG7AG67EEA5;PFPEE3H3@F7EA@FPFPDPEA>G7EB3DG@76;E5GEE;A@3H75G@67GJ;Q?7 3GF7GD #343E7676A@@P7E+D3@EB3D7@57*3@FP3PFPFP>P5:3D9P7>7 ?3;

(190)

(191) NB3DF;D6GE;F7 I74 GDAEADA5E GDAEADA5E 7EF G@ AGF;> ;@EB;DP 6G E;F7 3?PD;53;@ A>>3DEADA5E GDAEADA5E H;E7 N 835;>;F7D >;@F7DDA93F;A@ 7F >3 5A?BDP:7@E;A@ 67 >3 43E7 67 6A@@P7E +D3@EB3D7@57 *3@FP 7@ @7FFAK3@F 7F 7@ D79DAGB3@F >7E B3;7?7@FE B3D 53FP9AD;7E 7F B3D 4P@P8;5;3;D7E !> :3D?A@;E7 P93>7?7@F >;67@F;8;53F;A@ 67E ?P675;@E N >3;67 67 >7GD @G?PDA 6;67@F;8;53F;A@G@;CG763@E>7)PB7DFA;D7'3DF39P67E'DA87EE;A@@7>E67*3@FP>7)''* #7E )''*EA@F7@D79;EFDPE63@E>`@@G3;D7*3@FP3@@G3;D7 E3@F7 8DCG;;67@F;8;7>7EBDA87EE;A@@7>E 67E3@FP7F>7GDEE;FG3F;A@E67J7D5;57 #7E)''*67E#&A@FPFP;67@F;8;PEB3D*EGD>343E76G BDP@A?7F6G@A?BG;EE`;>K3H3;F67E5ADD7EBA@63@57E?G>F;B>7EB3D6PB3DF7?7@F67J7D5;57 BG;EB3D5A:PD7@577@FD7>3EBP5;3>;FP6`7J7D5;576G#&7F>76A?3;@767>3EA5;PFPE3H3@F7 *; 3G5G@75ADD7EBA@63@57@PF3;FFDAGHP763@E>`@@G3;D7*3@FP>7E5ADD7EBA@63@57EB3D@A?7F BDP@A?PF3;7@F78875FGP7E63@E>343E7+D3@EB3D7@57*3@FP #7E;@57DF;FG67EA@FPFPDPEA>G7EB3D ;@EB75F;A@?3@G7>>7B3D$ . .

(192) . . %&/5*'*$"5*0/&5&953"$5*0/%&4%0//<&4%&1"*&.&/54 @GF;>;E3@F>7@G?PDA6;67@F;8;53F;A@G@;CG76G)PB7DFA;D7'3DF39P67E'DA87EE;A@@7>E 67*3@FP)''*>7E6A@@P7ED7>3F;H7E3GJB3;7?7@FE67E#&CG;8;9GD7@F63@EGDAEADA5E A@FPFP3GFA?3F;CG7?7@F7JFD3;F7E %AGE3HA@EBD;E7@5A@E;6PD3F;A@>7E6A@@P7ENB3DF;D67>3 63F7 N >3CG7>>7 7>>7E PF3;7@F A4>;93FA;D7E N 6P5>3D7D 3H3@F397E 6G 7D <3@H;7D

(193) 3G 6P57?4D7

(194) 7F5A@H7@F;A@E7FDP?G@PD3F;A@E6G 7D<3@H;7D

(195) 3G 6P57?4D7

(196) #7E3H3@F397E5A?BD7@@7@FFAGF57CG;7EF355AD6PE3@E5A@FD7B3DF;77@@3FGD7AG7@ 7EBQ57E 6;D75F7?7@F AG ;@6;D75F7?7@F 6G@ ?A@F3@F EGBPD;7GD AG P93> N

(197) a F3J7E 5A?BD;E7E #7EDP?G@PD3F;A@ED7BDPE7@F7@F>7B3;7?7@FB3D>7E7@FD7BD;E7E6`G@7BD7EF3F;A@ 78875FGP7B3D>7BDA87EE;A@@7>67E3@FP6G@?A@F3@FEGBPD;7GDAGP93>N

(198) a #7E5A@H7@F;A@E EA@F 67E 355AD6E ;?B>;CG3@F 67E A4>;93F;A@E 67 >3 B3DF 6G BDA87EE;A@@7> 7F 67 >`7@FD7BD;E7 B3DF;5;B3F;A@NG@5A@9DQE35F;H;FP67D75:7D5:7AG67EE3;5>;@;CG735F;A@678AD?3F;A@7F5 #7E53D35FPD;EF;CG7E7F>363F7NB3DF;D67>3CG7>>7>7EB3;7?7@FEPF3;7@FA4>;93FA;D7EN6P5>3D7D EA@FBDPE7@FP7E63@E>7+$, +$,BDPE7@F7>7E53FP9AD;7E67>;7@E6;@FPDRF7F>363F7NB3DF;D67>3CG7>>7;>EA@F6U RFD76P5>3DPEEGD>343E7676A@@P7E+D3@EB3D7@57*3@FP #343E7+D3@EB3D7@57*3@FP3PFP BDPHG7B3D>3>A;7DFD3@667)7@8AD57?7@F67>3EP5GD;FP67E?P6;53?7@FE7F67EBDA6G;FE67 E3@FP676P57?4D7

(199) $3;E7>>7@3PFPAGH7DF7CG7@<G;>>7F

(200) 7@D3;EA@67>A@9G7E @P9A5;3F;A@EEGDE3?;E77@\GHD7 @FD7<3@H;7D

(201) 7F<G;@

(202) >7E6P5>3D3F;A@E67>;7@E 6;@FPDRFPF3;7@F83;F7EEGD>7EE;F7EI7467E7@FD7BD;E7EB:3D?357GF;CG7E B3DF;D67<G;>>7F

(203) ;>3PFPBAEE;4>767D7?B>;DDPFDA35F;H7?7@F>7E>;7@E6;@FPDRFEGD>343E7676A@@P7E !>K 36A@567E;@8AD?3F;A@E3@FPD;7GD7EN

(204) CG;EA@FFDQE;@5A?B>QF7E

(205) .

(206)

(207)

(208) . -DJI8:FJ>:HI6AADJUDJE6NUH6CH8DCIG:E6GI>:E6GJC: :CIG:EG>H:SJC68I:JG9:A6H6CIU9JC:K6A:JGHJEUG>:JG:S

(209) :JGDH-- 6IU<DG>:H9`6K6CI6<:HHJGA:H>I:9DCH 8DCIG>7JI>DC6J8DZI9UKUC:B:CIHEGDBDI>DCC:AH H8>:CI>;>FJ:HDJEGD;:HH>DCC:AH=U7:G<:B:CI=DHE>I6A>IU G:HI6JG6I>DCIG6CHEDGIIG6CHEDGI:I=DHE>I6A>IU9DCH:C C6IJG:9DCH9DCH9`6G<:CIHJ7K:CI>DCH;DGB6I>DC 9UE:CH:HEDJGH:GK>8:H:I8DCH:>AH=DCDG6>G:H6HHD8>6I>DC 9:86IU<DG>:G6IU:K>9:6JIG:

(210)

(211)

(212) DCIG6IH8DBEDGI6CI9:HD7A><6I>DCH9:A6E6GI9JBU9:8>C :I9:A>C9JHIG>: )6G:M:BEA:E6GI>8>E6I>DCSJC8DC<GVH :CI6CIFJ:8DC;UG:C8>:GD7A><6I>DCG:BEA>:E6GA: EGD;:HH>DCC:A6K:8E6>:B:CI9:H;G6>H9:IG6CHEDGI:I 9=U7:G<:B:CID7A><6I>DCG:BEA>:E6GA:CIG:EG>H: %:H 8DCK:CI>DCH8DC8:GC:CIA:H68I>K>IUH9:G:8=:G8=:A:H :HH6>H8A>C>FJ:HA6E6GI>8>E6I>DCSJC8DC<GVHH8>:CI>;>FJ: A:H68I>K>IUH9:;DGB6I>DC:I8

(213)

(214) )6>:B:CI9`JC:EG:HI6I>DC:;;:8IJU:E6GA:EGD;:HH>DCC:A 9:H6CIU9JC:K6A:JGHJEUG>:JG:S

(215) :JGDH-- . .

(216)

(217)

(218) . "9:CI>IU9:HE6GI>:H8DC8:GCU:HBDCI6CIC6IJG::I96I: 9:8=6FJ:EG:HI6I>DC (7A><6ID>G:9:EJ>HA6AD>9:

(219) GU:AA:B:CIEDHH>7A:9:9U8A6G:GHJGA:H>I:L:7:C

(220) . "9:CI>IU9:HE6GI>:H8DC8:GCU:H9:ADG<6C>H6I:JG9J CDB9:A696I::I9JA>:J9:AUKUC:B:CI9:A696I:9:A6 8DCK:CI>DC9:HDCD7?:IEGU8>HD7A><6ID>G:9:EJ>HA6AD> 9:

(221) GU:AA:B:CIEDHH>7A:9:9U8A6G:GHJGA:H>I::C

(222) :I9JBDCI6CID7A><6ID>G:9:EJ>HA6AD>9:

(223) GU:AA:B:CIEDHH>7A:9:9U8A6G:GHJGA:H>I::C

(224) "9:CI>IU9:HE6GI>:H7UCU;>8>6>G:;>C6A96I:9:E6>:B:CI BDCI6CIH>A:HIHJEUG>:JGDJU<6AS

(225) :JGDHEDHH>7A:9: 9U8A6G:GHJGA:H>I:9:EJ>H

(226) B6>HD7A><6ID>G:9:EJ>HA6 AD>9:

(227) .

(228) . . 3*/$*1"-&4.&463&4&5"/"-:4&%&4$3*15*7& #3?7EGD7BD;@5;B3>7PF3;F>7?A@F3@FFAF3>67E3H3@F397ED7OGEB3D>`7@E7?4>767E?P675;@E7F B3D>7E#&;67@F;8;PE3@@P7B3D3@@P767BG;E

(229) 7?A@F3@F3PFP6P5D;FB3D53FP9AD;7E67 >;7@E %AGE3HA@EGF;>;EP7F363BFP>7E53FP9AD;7EEBP5;8;CG7E6GDAE8ADA5E@AGE3HA@EGF;>;EP >7E 53FP9AD;7E D7EF3GD3F;A@ FD3@EBADF :AEB;F3>;FP :P47D97?7@F E7DH;57 7F 5A@E7;> 3GFD7 5A??7 63@E GDAE8ADA5E %AGE 3HA@E 8GE;A@@P >7E 53FP9AD;7E 6A@E 6A@E 7@ @3FGD76A@E7@7EBQ57EEG4H7@F;A@E8AD?3F;A@63@E>353FP9AD;76A@E EG4H7@F;A@E 8AD?3F;A@ %AGE 3HA@E 8GE;A@@P >7E 53FP9AD;7E 5A@FD;4GF;A@ 3GJ 5AUFE 6PHP@7?7@FE BDA?AF;A@@7>EE5;7@F;8;CG7EAGBDA87EE;A@@7>E7FFD3@EBADF7F:AEB;F3>;FP63@E>353FP9AD;7 5A@FD;4GF;A@3GJ5AUFE6PHP@7?7@FEBDA?AF;A@@7>E %AGE3HA@EA4F7@G53FP9AD;7E ,@7?7EGD7E75A@63;D73<AGFP73BAEF7D;AD;PF3;F>7@A?4D77F>7?A@F3@F67E53FP9AD;7E67 B3;7?7@FE 6;EBA@;4>7E 3BDQE

(230) 57EF N 6;D7 >7E 5A@H7@F;A@E 7F >7E DP?G@PD3F;A@E 7F >7 @A?4D7675A@H7@F;A@EE3@E?A@F3@F6P5>3DP6P5D;F7EBAGDFAGE>7E?P675;@E7F>7E#&3@@P7 B3D3@@P767BG;E

(231) #3 6;EFD;4GF;A@ 67E DPEG>F3FE ;@6;H;6G7>E 67E #& 39DP9PE BAGD 5:3CG7 EA5;PFP E3H3@F7 7EF P93>7?7@F BDPE7@FP7 #7E 6A@@P7E CG3@F;F3F;H7E A@F PFP 6P5D;F7E 7@ GF;>;E3@F >3 ?P6;3@7 ;@F7DH3>>7;@F7DCG3DF;>7!() #7EDPEG>F3FE4;@3;D7EA@FPFP6P5D;FEN>3;6767@BAGD57@F397 +AGF7E>7E3@3>KE7EA@FPFP78875FGP7EN>3;676G>A9;5;7>) . 0%*'*$"5*0/4%613050$0-& %AGE3HA@EBD;E7@5A?BF7>7E3H3@F397E6P5>3DPENB3DF;D67

(232) >3@@P7NB3DF;D67>3CG7>>7 ;>E67H3;7@FA4>;93FA;D7?7@FRFD76P5>3DPEEGD>343E73>ADECG7@AFD7BDAFA5A>7@7BDP5;E3;FB3E >363F7676P4GF #3?7EGD7E75A@63;D75A?BD7@3@F>7E5A@H7@F;A@E7F>7EDP?G@PD3F;A@E@783;E3;FB3EB3DF;767 @AFD7BDAFA5A>7;@;F;3>53D57E6P5>3D3F;A@E@PF3;7@FA4>;93FA;D7EN6P5>3D7DCGNB3DF;D67

(233) 7B7@63@F3BDQE3HA;D5A@EF3FPCG7>7EDP?G@PD3F;A@ED7BDPE7@F3;7@F3@@G7>>7?7@FB>GE67 8A;E >7 ?A@F3@F 67E 3H3@F397E 3BDQE

(234) @AGE 3HA@E 6P5;6P 6;@5>GD7 >7E 5A@H7@F;A@E 7F DP?G@PD3F;A@E53D@AGE3GD;A@EBG?3@CG7DG@7B3DF;7;?BADF3@F767E>;7@E7@FD7>7E?P675;@E 7F>;@6GEFD;7 #7BDAFA5A>7@7BDPHAK3;FB3E67E7G;>BAGD>7E6;88PD7@FE?A@F3@FE6P5>3DPE63@E>343E767 6A@@P7E 7B7@63@F 5A??7 @AGE 3HA@E ;67@F;8;P 67E H3>7GDE 67 B3;7?7@F 347DD3@F7E ;> 7EF 3BB3DG CG7 >3 43E7 67 6A@@P7E 5A@F7@3;F BDA434>7?7@F 67E 7DD7GDE B3D 7J7?B>7 57DF3;@E 3H3@F397E B7GH7@F 3HA;D PFP 6P5>3DPE 7@ 57@F;?7E B3D >7@FD7BD;E7 0>7E H3>7GDE 347DD3@F7E E7 F7D?;@3@F9P@PD3>7?7@FB3D67GJLPDAE1 %AGE3HA@E3>ADE6P5;6P67J5>GD7FAGE>7E?A@F3@FE EGBPD;7GDEN

(235)

(236)

(237)

(238)

(239) a

(240)

(241)

(242) BAGDG@E7G>B3;7?7@F 7>35ADD7EBA@6NA4E7DH3F;A@E 7JFDR?7E7@

(243) 7@

(244) EA;F

(245)

(246)

(247)

(248) 67E3H3@F397E?3;E?;>>;A@E67GDAE6G FAF3>7F 67

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

(250) . . '3DF;5;B3@FE %AGE 3HA@E ;67@F;8;P EA5;PFPE E3H3@F7E

(251) 67@FD7 7>>7E 3H3;7@F BDA6G;F 67E 9G;67E 67 BD3F;CG75>;@;CG77@

(252) 7F AG

(253) 67@FD77>>7E@3H3;7@FB3E67E;F7I74AGB3E674GD73G EGD>7GDE;F7I74 %AGE3HA@E;67@F;8;P

(254) #&67@FD77GJA@FPFPFDAGHPE63@E>343E767 6A@@P7E+D3@EB3D7@57*3@FP #7@A?4D767#&63@E5:3CG7EA5;PFPE3H3@F73>>3;F67 N 3H75G@7?P6;3@767 #&3BB3DF7@3;7@FNB>GE6G@7EA5;PFPE3H3@F7

(255) " ,) &D93@;9D3??7 . . . "#"4&3"/41"3&/$&"/5< #343E7676A@@P7EBG4>;CG7+D3@EB3D7@57*3@FP3@3>KEP767BG;E>7E;F7I74GDAEADA5E 5A@F7@3;F?;>>;3D6a 44V67>;7@EEGD3@E #7E3H3@F397ED7BDPE7@F3;7@F ?;>>;3D6E67GDAE>7E5A@H7@F;A@E ?;>>;3D6E67GDAE7F>7EDP?G@PD3F;A@E?;>>;3D6E 67GDAE #7E3H3@F397EEA@FA4>;93FA;D7EN6P5>3D7D67BG;E

(256) 7F>7E5A@H7@F;A@E7F DP?G@PD3F;A@EEA@FA4>;93FA;D7EN6P5>3D7D67BG;E

(257) #7E3H3@F397EEA@F6A@5BDPE7@FPE5; 67EEAGENB3DF;D67

(258) 7F>7E355AD6E DP?G@PD3F;A@ENB3DF;D67

(259) . 7"/5"(&4

(260) 'AGD>7@E7?4>767E?P675;@E3H3@F397EA@FPFP6P5>3DPEBAGDG@?A@F3@FFAF3>67 ?;>>;A@E6a?;>>;A@E67 ?;>>;A@E67V67

(261) N

(262) #7?A@F3@F?P6;3@ 6G@3H3@F397PF3;F67a!()

(263) V 67E#&A@F3G?A;@EG@3H3@F3976P5>3DP67

(264) N

(265) #7E3H3@F397E6P5>3DPEBAGD >7E#&D7BDPE7@F3;7@F

(266) 6G@A?4D7FAF3>67E3H3@F397E6P5>3DPE3GJ?P675;@E7F 6G?A@F3@FFAF3>67E3H3@F397E6P5>3DPE3GJ?P675;@EEA;F ?;>>;A@E6a ?;>>;A@E67 ?;>>;A@E67V #7?A@F3@F?P6;3@6G@3H3@F397BAGDG@#&PF3;F67

(267) a!()

(268) GFAF3>>7E3H3@F397E6P5>3DPEN>`7@E7?4>767E?P675;@EA@F6;?;@GP7@@A?4D77F7@ H3>7GD3G8;>6GF7?BEB3EE3@F67 ?;>>;A@6`3H3@F397EBAGD ?;>>;A@E6a7@

(269) N

(270)

(271)

(272) 3H3@F397EBAGD

(273) ?;>>;A@E6a . .

(274) .

(275) . #7@A?4D7>3H3>7GD7F>3BDABADF;A@673H3@F397E6P5>3DPE3GJ#&A@F6;?;@GP67 3H3@F397E

(276)

(277) 6G@A?4D7FAF3>67E3H3@F397E67E?P675;@EBAGD?;>>;A@E6a 67>3H3>7GDFAF3>767E3H3@F397E67E?P675;@EN

(278) 3H3@F397E

(279) 6G@A?4D7FAF3>67 3H3@F397E67E?P675;@EBAGD ?;>>;A@6a 67>3H3>7GDFAF3>767E3H3@F397E67E ?P675;@E #PHA>GF;A@3@@P7B3D3@@P7BAGD5:3CG753FP9AD;7EBP5;8;CG7673H3@F397E67

(280) N

(281) 7EFBDPE7@FP763@E>7+$, ,@7 3G9?7@F3F;A@ 67E H3>7GDE 6`3H3@F397E 6P5>3DPE 3 PFP 5A@EF3FP 63@E >7E 53FP9AD;7E 5A@FD;4GF;A@ 3G 5AUF 6`PHP@7?7@FE BDA?AF;A@@7>E E7DH;57E 7F 5A@E7;>E 7F 6A@E EG4H7@F;A@E 8AD?3F;A@ 'AGD>7@E7?4>767E?P675;@E>7?A@F3@F?P6;3@BAGDX5A@FD;4GF;A@ 3GJ5AUFE67EPHP@7?7@FEBDA?AF;A@@7>EY3PFP?G>F;B>;PB3D67

(282) N

(283) B3EE3@F67

(284) a !()

(285)

(286)

(287) N

(288) a !()

(289)

(290) 'AGD >7E #& >7 ?A@F3@F ?P6;3@ BAGD X5A@FD;4GF;A@3GJ5AUFE67EPHP@7?7@FEBDA?AF;A@@7>EY7EFB3EEP67

(291) a!()

(292) N a!()

(293) 'AGD>7@E7?4>767E?P675;@E>7?A@F3@F?P6;3@BAGDXE7DH;57E7F5A@E7;>EY3PFP?G>F;B>;P B3D67

(294) N

(295) B3EE3@F67a!()

(296) N a!() 'AGD>7E#&>7 ?A@F3@F?P6;3@BAGDXE7DH;57E7F5A@E7;>EY3PFP?G>F;B>;PB3D67

(297) N

(298) B3EE3@F67

(299) a!()

(300) N a

(301) 'AGD>7@E7?4>767E?P675;@E>7?A@F3@F?P6;3@BAGDX6A@E EG4H7@F;A@E]8AD?3F;A@Y3 PFP?G>F;B>;PB3D67

(302) N

(303) B3EE3@F67 a!()

(304) Na!() 'AGD >7E#&>7?A@F3@F?P6;3@BAGDX6A@E EG4H7@F;A@E 8AD?3F;A@Y7EFD7EFPEF34>7B3EE3@F67a !()

(305) N

(306) a!()

(307) #7EFDA;E53FP9AD;7E6`3H3@F397ECG;D7BDPE7@F3;7@F>7EB>GE;?BADF3@F7EBDABADF;A@E7@@A?4D7 7F7@H3>7GDFAF3>7PF3;7@F>7E?R?7EBAGD>7E?P675;@E#&7F@A@ #&D7EF3GD3F;A@FD3@EBADF 7F:P47D97?7@F 'AGD>7@E7?4>767E?P675;@E>3D7EF3GD3F;A@D7BDPE7@F3;F6G@A?4D77F 67>3H3>7GD67E3H3@F397E

(308) ?;>>;A@E6à>7FD3@EBADFD7BDPE7@F3;F6G@A?4D77F 67 >3 H3>7GD 67E 3H3@F397E

(309)

(310) ?;>>;A@E 6à 7F >:P47D97?7@F D7BDPE7@F3;F 6G @A?4D7 7F 67 >3 H3>7GD 67E 3H3@F397E ?;>>;A@E 6à 'AGD >7E #& >3 D7EF3GD3F;A@ D7BDPE7@F3;F 6G @A?4D7 7F 67 >3 H3>7GD 67E 3H3@F397E ?;>>;A@ 67GDAE >7 FD3@EBADF 6G @A?4D7 7F 67 >3 H3>7GD 67E 3H3@F397E ?;>>;A@E 67GDAE >:P47D97?7@F 6G@A?4D77F 67>3H3>7GD67E3H3@F397E?;>>;A@E67GDAE . .

(311) . !% )# ! % !. . $, $A@F3@F?P6;3@!()67E3H3@F397E67E?P675;@E#&7F@A@ #&7@7GDAEa !%

(312) % % . .

(313) .

(314)

(315) .

(316) .

(317) . . . .

(318) . . . . .

(319) . . . % . .

(320) .

(321)

(322) . .

(323)

(324) .

(325) .

(326) . .

(327)

(328) .

(329) .

(330) . . . % . .

(331)

(332) .

(333) .

(334)

(335) .

(336) .

(337) .

(338) .

(339) .

(340) .

(341) .

(342) .

(343) .

(344) . % . . . .

(345) .

(346) . . . . . .

(347) .

(348) . ! "! " '! )%#& ! ! "# ! !. % . .

(349) .

(350) . .

(351)

(352)

(353)

(354) .

(355)

(356) .

(357) .

(358) .

(359) .

(360) .

(361) . .

(362) . % . . .

(363) . . .

(364)

(365) .

(366)

(367)

(368) .

(369) .

(370)

(371)

(372) .

(373) .

(374)

(375)

(376) . . # ! . % . . .

(377) .

(378) .

(379) .

(380)

(381) . . .

(382) .

(383) .

(384) . .

(385)

(386) . % . .

(387) . .

(388) . .

(389) . .

(390)

(391) .

(392)

(393)

(394) .

(395)

(396) .

(397) .

(398) .

(399)

(400) .

(401) .

(402) . .

(403) . . . . . . ! !%. !" !. !. . "!. . . % . . .

(404) . . #39D3@67?3<AD;FP67EEA5;PFPEE3H3@F7E3H3;F3G?A;@EG@?7?4D767>7GD4GD73G3K3@F 7G3G?A;@EG@3H3@F3976P5>3DP67BG;E

(405) '3DEA5;PFPE3H3@F7>7?A@F3@FFAF3>?P6;3@67E 3H3@F397E 6P5>3DPE BAGD >7@E7?4>7 67 >7GDE #& D7EB75F;8E 67

(406) N

(407) PF3;F 67

(408)

(409)

(410) a !()

(411)

(412)

(413)

(414)

(415)

(416)

(417)

(418)

(419)

(420)

(421)

(422)

(423) V?3;EH3D;3;F8ADF7?7@F6G@73EEA5;3F;A@N>3GFD7 67EEA5;PFPEE3H3@F7E36P5>3DPG@FAF3>67

(424) aB3D3@7@3H3@F397EBAGD>7GD#& 67E EA5;PFPEE3H3@F7E3H3;7@F?A;@E67

(425)

(426)

(427) aB3D3@6`3H3@F397E6P5>3DPEBAGD>7GD#& 67E EA5;PFPEE3H3@F7E3H3;7@F7@FD7

(428)

(429)

(430) a7F

(431)

(432)

(433)

(434) a3GFAF3>B3D3@7@3H3@F397E6P5>3DPEBAGD>7GD #& 67EEA5;PFPEE3H3@F7E3H3;7@F7@FD7

(435)

(436)

(437)

(438) a7F

(439)

(440)

(441)

(442) a3GFAF3>B3D3@7@3H3@F397E 6P5>3DPEBAGD>7GD#& 67EEA5;PFPEE3H3@F7E3H3;7@FB>GE67

(443)

(444)

(445)

(446) a3GFAF3>B3D3@7@ 3H3@F397E6P5>3DPEBAGD>7GD#& . 0/7&/5*0/4

(447) 'AGD>7@E7?4>767E?P675;@E;>K3H3;F ?;>>;A@E675A@H7@F;A@E6P5>3DP7E ?;>>;A@E 675A@H7@F;A@E3H3;7@F>7GD?A@F3@F535:P

(448)

(449)

(450) 5A@H7@F;A@E3H3;7@FG@?A@F3@F 6P5>3DPBAGDG@FAF3>67 ?;>>;A@E6a ?;>>;A@E67 ?;>>;A@E67V67

(451) N

(452) #7E5A@H7@F;A@E6P5>3DP7E3GJ#&D7BDPE7@F3;7@F

(453) 67FAGF7E>7E5A@H7@F;A@E 6P5>3DP7E3GJ?P675;@E7F67>7GDH3>7GDEA;F?;>>;A@E6à?;>>;A@E67?;>>;A@E 67VBAGD>7E 675A@H7@F;A@E3H75?A@F3@F 5A@H7@F;A@E3H3;7@F>7GD ?A@F3@F535:P GFAF3>BAGDFAGE>7E?P675;@E>3H3>7GD67E5A@H7@F;A@E6P5>3DP7E33G9?7@FP67 ?;>>;A@E6a7@

(454) N?;>>;A@E6a7@

(455) #7@A?4D77F>3H3>7GD67E5A@H7@F;A@E67E #&36;?;@GP5A??7>7?A@FD7>3" ,) #PHA>GF;A@3@@P7B3D3@@P76G?A@F3@FFAF3>6G@A?4D7675A@H7@F;A@E3H75?A@F3@F535:P >7@A?4D7675A@H7@F;A@E3H75G@?A@F3@F7F>7?A@F3@F?P6;3@67E5A@H7@F;A@EEA@F BDPE7@FPE63@E>7+$, 'AGD>`7@E7?4>767E?P675;@E>7@A?4D7675A@H7@F;A@E3G?A@F3@F535:P36;?;@GP67

(456)

(457)

(458) 7@

(459) N

(460)

(461)

(462) 7@

(463) #7@A?4D7>3H3>7GD7F>3BDABADF;A@67E5A@H7@F;A@E6P5>3DP7E3GJ#&A@F6;?;@GP5:3CG7 3@@P7B3EE3@F67

(464)

(465) 5A@H7@F;A@E

(466) 6G@A?4D7675A@H7@F;A@EBAGD>7E?P675;@E7F ?;>>;A@67GDAE67>3H3>7GD67E5A@H7@F;A@EBAGD>7E?P675;@E7@

(467) N

(468)

(469) 5A@H7@F;A@E

(470) 6G@A?4D7675A@H7@F;A@EBAGD>7E?P675;@E7F ?;>>;A@67GDAE 67>3H3>7GD67E5A@H7@F;A@EBAGD>7E?P675;@E7@

(471) #7@A?4D7675A@H7@F;A@E3H75?A@F3@F535:PBAGD>7E#&36;?;@GP67

(472)

(473)

(474) 7@

(475) N

(476)

(477) 7@

(478) '3DEA5;PFPE3H3@F7>7?A@F3@FFAF3>?P6;3@67E5A@H7@F;A@E6P5>3DP7EBAGD>7GD#&D7EB75F;8E 67

(479) N

(480) PF3;F67

(481)

(482) a!()

(483) N

(484)

(485)

(486)

(487)

(488) V . .

(489) . . $,$A@F3@FFAF3>@A?4D7675A@H7@F;A@E3H75?A@F3@F535:P7F?A@F3@F?P6;3@ !()67E5A@H7@F;A@E?A@F3@FFAF3>7F?P6;3@!()67EDP?G@PD3F;A@E67E?P675;@E#&7F @A@ #&3@@P7B3D3@@P767BG;ECG`;>EEA@FA4>;93FA;D7EN6P5>3D7D #! . %. . . %"%! .

(490)

(491) . . . . . .

(492) . '%)'&-&+#'&* -%'&+&+"0 (',)&+!,&'%) '&-&+#'&* $,)+'+$* '&-&+#'&*- %'&+&+0$)0&2 '%)'&-&+#'&* -,&%'&+&+0$)0 &2 '%)'&-&+#'&* -%'&+&+"0 (',)&+!,&'%) '&-&+#'&* $,)+'+$* '&-&+#'&*- %'&+&+0$)0&2 '%)'&-&+#'&* -,&%'&+&+0$)0 &2 '&+&++'+$&2. . . . .

(493) . .

(494) .

(495) . . .

(496) . . . . 0#& '%) )0%,&0)+#'&* '&+&++'+$&2 0#& '%) )0%,&0)+#'&*.

(497) . . .

(498) .

(499) . . . . .

(500) .

(501) .

(502)

(503) .