Conclusion et suggestions

T. gondii est présent et circule chez les petits ruminants destinés à la consommation humaine au Sud Bénin. L’infection est beaucoup plus élevée chez les chèvres en élevage familial au Sud que chez les ovins en provenance du Nord Bénin. Ce résultat met en exergue la forte contamination de l’environnement par les oocystes de T. gondii excrétéb s par les chats et la forte exposition des populations au risque d’infection humaine. Des campagnes de sensibilisation devraient donc être entreprises par les autorités en charge de la santé publique pour informer la population béninoise par rapport aux risques et aux mesures de prévention.

Références bibliographiques

1. Acha N. et Szyfres B., 1989. Zoonoses et maladies transmissibles communes à l’homme et aux animaux .OIE. Paris France. p 677- 691

2. AFSSA., 2005. Toxoplasmose : état des connaissances et évaluation du risque lié à l’alimentation. Rapport du groupe de travail « Toxoplasma gondii» de l’Afssa : 318p.

3. Ajzenberg, D., Banuls, A. L., Su, C., Dumetre, A., Demar, M., Carme, B., & Dardé, M.

L., 2004. Genetic diversity, clonality and sexuality in Toxoplasma gondii. International journal for parasitology, 34(10), 1185-1196.

4. Ajzenberg, D., Collinet, F., Mercier, A., Vignoles, P., & Dardé, M. L., 2010.

Genotyping of Toxoplasma gondii isolates with 15 microsatellite markers in a single multiplex PCR assay. Journal of clinical microbiology, 48(12), 4641-4645.

5. Akpovi, J., Kone, M., Takpara, I., Perrin, R., Massougbodji, A., & ALIHONOU, E., 1998. Grossesse et toxoplasmose à Cotonou. Le Bénin Médical, 1-4.

6. Alexander J, Stinson WH., 1988. Sex hormones and the course of parasitic infection.

Parasitol Today 4:189–193.

7. Al-Mabruk, A.A., Alkhunfas, S.R., El-Buni, A.A., Annajar, B.B., Elsaid, M.M.A., 2013. Seroprevalence of Toxoplasma gondii antibodies in sheep from Libya. Int. J. Adv.

Res. 1, 148–154.

8. Boothroyd, J. C. and Grigg, M.E.,2002. "Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease?" Curr.

Opin. Microbiol., 5(4):438-42.

9. Buxton, D., Maley, S.W., Wright, S.E., Rodger, S., Bartley, P. and Innes, E.A.,2007.

Toxoplasma gondii and ovine toxoplasmosis: New aspects of an old story. Vet.

Parasitol., 149(1): 25-28.

10. Davoust, B., Mediannikov, O., Roqueplo, C., Perret, C., Demoncheaux, J.-P., Sambou, M., Guillot, J., Blaga, R., 2015. Enquête de séroprévalence de la toxoplasmose animale au SénégalSerological survey of animal toxoplasmosis in Senegal. Bull. Société Pathol.

Exot. 108, 73–77.

11. Dubey JP, Beattie CP.,1988. Toxoplasmosis of Animals and Man. CRC Press, Boca Raton, FL, USA, P. 220.

12. Dubey, J.P. and Jones, J.L., 2008. Toxoplasma gondii infection in humans and animals in the United States. Int. J. Parasitol., 38(11): 1257-1278.

13. Dubey, J.P.,2001. Oocyst shedding by cats fed isolated bradyzoites and comparison of infectivity of bradyzoites of the VEG strain Toxoplasma gondii to cats and mice.

J. Parasitol., 87: 215-219.

14. Dubey, J.P.,2009. Toxoplasmosis in sheeps: The last 20 years. Vet. Parasitol., 152: 25-80.

15. Dubey, J.P.,2016. Toxoplasmosis of Animals and Humans. 2^nd ed. CRC Press, Florida, USA.

16. Dumètre, A., Le Bras, C., Baffet, M., Meneceur, P., Dubey, J.P., Derouin, F., Duguet, J.P., Joyeux, M. and Moulin, L.,2008. Effects of ozone and ultraviolet radiation treatments on the infectivity of Toxoplasma gondii oocysts. Vet. Parasitol., 153(3- 4):209-213.

17. EFSA. (2007). Surveillance and monitoring of Toxoplasma in humans, food and animals, scientific opinion of the panel on biological hazards. EFSA Journal, 583, 1–

64.

18. Ferguson, D.J., 2009. Toxoplasma gondii: 1908-2008, homage to Nicolle, Manceaux and Splendore. Mem. Inst. Oswaldo Cruz., 104(2): 133-148.

19. Frenkel, J.K., 2000. Biology of Toxoplasma gondii. In Ambroise-Thomas, P., Petersen, E., (Eds) Congenital toxoplasmosis: scientific background, clinical management and control, Springer, Paris, Pp.9-25.

20. Freyre, A., Bonino, J., Falcón, J., Castells, D., Correa, O., & Casaretto, A., 1997. The incidence and economic significance of ovine toxoplasmosis in Uruguay. Veterinary parasitology, 73(1-2), 13-15.

21. Gebremedhin, E.Z., Abdurahaman, M., Hadush, T., Tessema, T.S., 2014.

Seroprevalence and risk factors of Toxoplasma gondii infection in sheep and goats slaughtered for human consumption in Central Ethiopia. BMC Res. Notes 7, 696.

22. Halos, L., Thébault, A., Aubert, D., Thomas, M., Perret, C., Geers, R., Alliot, A., Escotte-Binet, S., Ajzenberg, D., Dardé, M.-L., Durand, B., Boireau, P., Villena, I., 2010. An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France. Int. J. Parasitol. 40, 193–200 23. Innes, E. A., & Mattsson, J. G., 2007. Neospora caninum emerges from the shadow of

Toxoplasma gondii. Trends in parasitology, 23(2) : 43-44.

24. Innes, E. A.,2010. A brief history and overview of Toxoplasma gondii. Zoonoses and public health, 57(1) : 1-7.

25. Kasper, L.H., 2005. Toxoplasma infection.16th edition, New York, McGraw-Hill, pp.1243–1247.

26. Khan, A., Su, C., German, M., Storch, G.A., Clifford, D.B. and Sibley, L.D., 2005.

Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains. J. Clin. Microbiol., 43:5881-5887.

27. Kijlstra, A. and Jongert, E., 2009. Control of the risk of human toxoplasmosis transmitted by meat. Int. J. Parasitol., 38: 1359-1370.

28. Majumdar, D., 2010. Study of population diversity of Toxoplasma gondii. MSc thesis, University of Tennessee, Knoxville. http://trace.tennessee.edu/utk_gradthes/818.

29. Masala, G., Porcu, R., Madau, L., Tanda, A., Ibba, B., Satta, G., & Tola, S., 2003.

Survey of ovine and caprine toxoplasmosis by IFAT and PCR assays in Sardinia, Italy.

Veterinary parasitology, 117(1): 15-21.

30. McLeod, R., Boyer, K.M., Lee, D., Mui, E., Wroblewski, K., Karrison, T., Noble, A.G., Withers, S., Swisher, C.N., Heydemann, P.T., Sautter, M., Babiarz, J., Rabiah, P., Meier, P. and Grigg, M.E., 2012.Toxoplasmosis study group. Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009).

Clin. Infect. Dis., 54(11):1595–1605.

31. Moncada, P.A. and Montoya, J.G., 2012. Toxoplasmosis in the fetus and newborn: An update on prevalence, diagnosis and treatment. Expert. Rev. Anti Infect. Ther., 10(7):

815-828.

32. Montoya, J. G. and Liesenfeld, O., 2004. Toxoplasmosis. Lancet, 363:1965-1976.

33. Ngoungou, E. B., Bhalla, D., Nzoghe, A., Dardé, M. L., & Preux, P. M., 2015.

Toxoplasmosis and epilepsy—systematic review and meta analysis. PLoS Negl Trop Dis, 9(2): e0003525.

34. Ogouyèmi-Hounto, A., Agbayahoun-Chokki, F., de Tove, Y. S. S., Bankole, B. B., de Souza, V. A., Assogba, M., ... & Massougbodji, A., 2014. Évaluation d’un test de diagnostic rapide pour le diagnostic de la toxoplasmose chez les femmes enceintes à Cotonou (Bénin). Bulletin de la Société de pathologie exotique, 107(2) : 85-89.

35. Radke, J.R. and White, M.W., 1998. A cell cycle model for the tachyzoite of Toxoplasma gondii using the Herpes simplex virus thymidine kinase. Mol. Biochem.

Parasitol., 94:237-247.

36. Radostits, O.M., Gay, C.C., Hinchcliff, K.W., Constable, P.D.,2006. Veterinary Medicine: A textbook of the diseases of cattle, horses, sheep, pigs and goats. 10th edn.

Saunders, London, pp.1518--‐1522.

37. Robert-Gangneux, F., 2014. It is not only the cat that did it: How to prevent and treat congenital toxoplasmosis. J. Infect., 68, S125eS133.

38. Samraa, N.A., McCrindle, C.M.E., Penzhorn, B.L., Cenci-Goga, B., 2007.

Seroprevalence of toxoplasmosis in sheep in South Africa. J. S. Afr. Vet. Assoc. 78, 116–120.

39. Sibley, L.D., Khan, A., Ajioka, J.W. and Rosenthal, BM., 2009. Genetic diversity of Toxoplasma gondii in animals and humans. Phil. Trans. R. Soc. B., 364:2749-2761.

40. Swai, E.S., Kaaya, J.E., 2012. A survey of Toxoplasma gondii antibodies by latex agglutination assay in dairy goats in Northern Tanzania. Trop. Anim. Health Prod. 45, 211–217.

41. Tenter, A.M., Heckerotha, A.R. and Weiss, L.M., 2000. Toxoplasma gondii: From animals to humans. Int. J. Parasitol., 30: 1217-1258.

42. Teshale, S., Dumetre, A., Dardé, M.-L., Merga, B., Dorchies, P., 2007. Serological survey of caprine toxoplasmosis in Ethiopia: prevalence and risk factors. Parasite 14, 155–159.

43. Van der Puije, W.N.A., Bosompem, K.M., Canacoo, E.A., Wastling, J.M., Akanmori, B.D., 2000. The prevalence of anti-Toxoplasma gondii antibodies in Ghanaian sheep and goats. Acta Trop. 76, 21–26.

44. Villena I, Durand B, Aubert D, Blaga R, Geers R, Thomas M, Perret C, Alliot A, Escotte-Binet S, Thebault A, Boireau P, Halos L., 2012. New strategy for the survey of Toxoplasma gondii in meat for human consumption. Veterinary Parasitology, 183(3–

4), 203–208.