[PDF] Top 20 Thymus dysfunction in the development of type 1 diabetes and endocrine autoimmune diseases
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Thymus dysfunction in the development of type 1 diabetes and endocrine autoimmune diseases
... demonstrated the crucial role played by the thymus in programming central ...More and more experimental arguments argue for a defect in thymic (central) tolerogenic function as ... Voir le document complet
3
Thymus and Type 1 diabetes: Where are we now?
... that: 1° IGF-2 is the dominant tolerogenic precursor of the family and mediates cross- tolerance to insulin; 2° A thymus dysfunction plays a crucial role in ... Voir le document complet
1
Hematopoietic progenitor populations for cell therapy of autoimmune diseases : characterization and comparison of their mechanism of action in Type I Diabetes and Experimental Autoimmune Encephalomyelitis
... cells The existence of populations, which can negatively regulate autoimmune responses, is one of the most important discoveries in the field of cellular therapies ... Voir le document complet
249
Role of Checkpoint Inhibitory Molecules in the development of Type 1 Diabetes
... Peón, and Terrazas ...implicated in the later stages of ...capacity and ultimately cytotoxic function) were unable to cause diabetes post monocyte depletion, and it was ... Voir le document complet
73
Virus infections in pathogenesis of type 1 diabetes
... More and more experimental evidence demon- strates that EV infection, and CVB infection in particular, plays an important role in the etiolo- gy of a still unknown percentage ... Voir le document complet
4
Programing of the autoimmune diabetogenic response in the thymus during fetal and perinatal life
... view of the thymus as the primary rampart against autoimmunity culminated with the identification by positional cloning of the AutoImmune REgulator (AIRE) gene ... Voir le document complet
6
Thymus, central T cell self-tolerance and type 1 diabetes
... investigation of neuroendocrine genes expressed in the thymus has led to the identifi- cation of neuroendocrine ...Through the study of insulin-related gene ... Voir le document complet
4
Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-defensin 14 Expression in Pancreatic Endocrine Cells Preventing Autoimmune Diabetes
... molecules of the immune system found in almost all plants and ...defensins and regenerating islet-derived proteins, are mainly expressed at the epithelial surfaces and due ... Voir le document complet
68
Associations between HLA and autoimmune neurological diseases with autoantibodies
... Description of new Ab has enabled to establish more accurate diagnosis and to expand our knowledge about autoimmune neurological ...However, the pri- mary trigger that promotes the ... Voir le document complet
14
Genetic Restoration of Heme Oxygenase-1 Expression Protects from Type 1 Diabetes in NOD Mice
... Discussion Type 1 diabetes is a complex multifactorial autoimmune disease in which genetic factors play a critical ...insulin-dependent diabetes (Idd) loci, have been identified ... Voir le document complet
14
Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies
... stage in the process of immune response by coordinating with different immune ...critical in generation, sustenance and regulation of immune response against pathogens as well as ... Voir le document complet
34
Arterial pulse pressure increases according to diabetes duration, independently of age in patients with type 1 diabetes
... higher in diabetic patients than in controls (44 vs 27 %, p < ...0.05). The difference in PP between the four groups of diabetic patients, already present in standing ... Voir le document complet
2
Remission with ursodeoxycholic acid of type 1 autoimmune hepatitis resistant to azathioprine and steroids.
... (17). In a recent study by Czaja et al. of a small cohort of patients, short term UDCA therapy improved serum aspartate aminotransferase (AST) levels but did not improve the liver histology or ... Voir le document complet
16
Global epidemiology of type 1 diabetes in young adults and adults: a systematic review
... review of the literature was performed to retrieve original papers in English, French and Spanish published up to November 6, 2014, reporting the incidence of T1D among ... Voir le document complet
16
CpG Methylation Changes within the IL2RA Promoter in Type 1 Diabetes of Childhood Onset
... Differences in DNA methylation of the IL2RA promoter between T1D and non-diabetic controls were analyzed using non-parametric Wilcoxon rank sum ...measures the proportion of ... Voir le document complet
8
Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice
... Journal of Diabetes Research 7 4. Discussion In the present study, we provide evidence that histamine deficiency causes a delay in diabetes onset and decreases its ... Voir le document complet
11
Covariation of the Incidence of Type 1 Diabetes with Country Characteristics Available in Public Databases
... that the incidence of Type 1 Diabetes (T1D) is highly variable from one country to ...example, the 62.42/100.000 persons/year incidence found in Finland [ 1 ] was ... Voir le document complet
13
Type 1 diabetes susceptibility loci from genome scans in multiplex families
... USA and Scandi- navia) and one set of 254 families newly assem- bled for this ...merging and joint analyses of existing families are required to clar- ify the role of ... Voir le document complet
2
en fr Pathophysiology of the endothelium : Application on angiogenesis induced by DEET-based mosquito repellents and type 1 diabetes-induced endothelial dysfunction Physiopathologie de l’endothélium : Applications à l’angiogenèse induite par les répulsifs anti-moustiques à base de DEET et à la dysfonction endothéliale dans le cadre du diabète de type 1
... pro-angiogénique in vitro et in vivo du DEET, un répulsif ...conduit, in fine, à une augmentation de la croissance tumorale sur un modèle de xénogreffe de tumeur chez la ... Voir le document complet
158
Similar pulse pressure and sytolic blood pressure x heart rate double product in middle-age patients with type 1 diabetes and with type 2 diabetes.
... Division of Diabetes, Nutrition & Metabolic Disorders, Department of Medicine, CHU Sart Tilman, B-4000 Liège, ...factor in both patients with type 1 (T1DM) and ... Voir le document complet
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