[PDF] Top 20 A STAT3 Gene Expression Signature in Gliomas is Associated with a Poor Prognosis.
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A STAT3 Gene Expression Signature in Gliomas is Associated with a Poor Prognosis.
... that STAT3 phosphorylation in glioblastomas and anaplastic astrocyotmas, as assessed by immunohistochem- istry, correlates with expression of mutant EGF receptors (EGFRvIII), and was not ... Voir le document complet
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An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment
... conditions in vitro. In this way, we managed to capture a common response to hypoxia, which we then applied in PDA patient ...the signature in PDA was con firmed by showing that ... Voir le document complet
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Expression of long non-coding RNA ANRIL predicts a poor prognosis in intrahepatic cholangiocarcinoma
... involved in cell cycle progression 16 ...cancer associated 1 (UCA1) lncRNA was reported to promote CCA formation and progression by activating a proliferative AKT/GSK-3β/CCND1 axis and by inducing ... Voir le document complet
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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
... factors is capable, on its own, of inducing an EMT in the human mammary epithelial (HMLE) cell ...up-regulates a subset of other EMT-inducing TFs, with Twist, Zeb1, Zeb2, TGF-β1, and FOXC2 ... Voir le document complet
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Altered Expression of the Transcription Factor Forkhead Box A1 (FOXA1) Is Associated With Poor Prognosis in Urothelial Carcinoma of the Upper Urinary Tract
... differences in the prevalence of mutations in genes in UTUC compared to bladder ...mutations in FGFR3, HRAS and CDKN2B were shown to be more common in UTUC, while TP53 and ARID1A ... Voir le document complet
19
Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme
... modifications in miRNA is an emerging research area in the epitranscriptomics ...methylation in mature ...(5mC) in miRNA abolishes their repres- sive function towards the gene ... Voir le document complet
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“Fibrous nests” in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome
... 5 with tumor fibrosis ...which is a myofibroblast activation ...were associated with high scores of fibrosis in 78 HCCs ...3A). In non-tumor livers, fibrosis was graded by ... Voir le document complet
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PDL1 expression is associated with longer postoperative, survival in adrenocortical carcinoma
... cancers associated with a very poor ...inhibitors is an attractive novel therapeutic strategy for poor-prognosis ...including in advanced ACC. However, PDL1 ... Voir le document complet
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Hypoxia-associated factor expression in low-grade and anaplastic gliomas: a marker of poor outcome
... there is evidence that neurospheres derived from different regions of the developing or adult brain display unique characteristics with regards to growth, differentiation and gene expression ... Voir le document complet
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Helicase-like transcription factor expression is associated with a poor prognosis in Non-Small-Cell Lung Cancer (NSCLC)
... function in gene transcription [ 6 ], cell cycle [ 7 ], DNA re- pair [ 8 , 9 ], and genome stability maintenance [ 10 ], sup- porting its tumor suppressor ...role. In cancer, two different ... Voir le document complet
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Identification of a three-gene expression signature of poor-prognosis breast carcinoma.
... chosen with the assistance of the computer programs Oligo ...searches in dbEST, htgs and nr databases to confirm the total gene specificity of the nucleotide sequences chosen for the primers and ... Voir le document complet
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Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells -high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation
... CXXC5 gene encodes a transcriptional activator with a zinc-finger domain, and high expression in human acute myeloid leukemia (AML) cells is associated with ... Voir le document complet
19
Low lamin A expression in lung adenocarcinoma cells from pleural effusions is a pejorative factor associated with high number of metastatic sites and poor performance status
... involved in the alternative production of lamins A and C are still ...prelamin A pro- tein produced in HGPS (Hutchinson-Gilford Progeria Syndrome) cells and during physiologi- cal aging) [ 4 , ... Voir le document complet
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A SNAP25 promoter variant is associated with early-onset bipolar disorder and a high expression level in brain.
... out with PLINK ...haplotypes in sliding windows of a fixed number of SNPs, varying from two to seven and shifting by one SNP at a ...tests with one degree of ... Voir le document complet
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A gene expression signature shared by human mature oocytes and embryonic stem cells.
... provide a global view of how the various sample groups were ...out with CLUSTER and TREEVIEW software ...PS with the highest coeffi- cient of variation (CV). Gene expression profiles ... Voir le document complet
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ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer
... HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from ... Voir le document complet
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The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival
... stored in liquid nitrogen. Random sections of each tumor were analyzed under a light microscope after hematoxylin–eosin staining to determine the extent of necrosis and the percentage of tumor ...enriched ... Voir le document complet
8
Presence of bone metastases(BM) at diagnosis is associated with poor prognosis and coagulation disorders (CD) in patients (pts) with advanced gastric cancer (AGC)
... BM in AGC is a relatively uncommon finding and has a poor prognosis [Leporini ...occurs in approximately 10-15% of pts with ...study is to describe the main ... Voir le document complet
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Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet
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The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis
... factors in breast carcinogenesis, we performed a comparative study of their expression at both the RNA and protein levels in a series of human breast ...mRNA expression and ... Voir le document complet
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