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[PDF] Top 20 Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies

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Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies

Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies

... our patients were at high risk of GVHD and non-relapse mortal- ity because of their ages and comorbidities, the use of rabbit anti-thymoglobulin was of particular ...most patients (54%) who suffered from ... Voir le document complet

8

Allogenic hematopoietic stem cell transplantation after reduced intensity conditioning regimen for elderly patients (60 years and older) with hematologic malignancies using unrelated donors: a retrospective study for the French society for stem cell trans

Allogenic hematopoietic stem cell transplantation after reduced intensity conditioning regimen for elderly patients (60 years and older) with hematologic malignancies using unrelated donors: a retrospective study for the French society for stem cell transplantation (SFGM-TC)

... of allogeneic hematopoietic stem cell trans- plantation (allo-HSCT) from unrelated donors (URD) has drastically increased in the past ...years. To date, there are limited data on the ... Voir le document complet

4

Similar outcome of allogeneic stem cell transplantation after myeloablative and sequential conditioning regimen in patients with refractory or relapsed acute myeloid leukemia: A study from the Societe Francophone de Greffe de Moelle et de Therapie Cellula

Similar outcome of allogeneic stem cell transplantation after myeloablative and sequential conditioning regimen in patients with refractory or relapsed acute myeloid leukemia: A study from the Societe Francophone de Greffe de Moelle et de Therapie Cellulaire.

... date, allogeneic hematopoietic stem cell transplantation (HSCT) is the only potentially curative approach in patients with primary induction failure (PIF) or ... Voir le document complet

8

Anti-thymocyte globulin for graft-versus-host disease prophylaxis in patients with intermediate- or high-risk acute myeloid leukaemia undergoing reduced-intensity conditioning allogeneic stem cell transplantation in first complete remission - a survey on

Anti-thymocyte globulin for graft-versus-host disease prophylaxis in patients with intermediate- or high-risk acute myeloid leukaemia undergoing reduced-intensity conditioning allogeneic stem cell transplantation in first complete remission - a survey on behalf of the Acute Leukaemia Working Party of the European Society for Blood and Marrow Transplantation

... aimed to explore the role of high and intermediate doses of ATG administered as part of RIC in adult high-risk AML patients transplanted while in first complete remission ...conducted ... Voir le document complet

4

Salvage use of allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning from unrelated donors in multiple myeloma. A study by the plasma cell disorders subcommittee of the european group for blood and marrow transplant chron

Salvage use of allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning from unrelated donors in multiple myeloma. A study by the plasma cell disorders subcommittee of the european group for blood and marrow transplant chronic malignancies working party

... 86 patients between 2001 and 2011. In both of these aforementioned studies, myeloablative chemotherapy and RIC were included, along with patients with different allo-HSCT indications ... Voir le document complet

4

Allogeneic hematopoietic stem cell transplantation for T-prolymphocytic leukemia: a report from the French society for stem cell transplantation (SFGM-TC)

Allogeneic hematopoietic stem cell transplantation for T-prolymphocytic leukemia: a report from the French society for stem cell transplantation (SFGM-TC)

... 2009), with more than half of the patients receiving a reduced- intensity conditioning regimen (Table ...associated with a better outcome, and this might be due to the ... Voir le document complet

5

Alternative donor hematopoietic stem cell transplantation for mature lymphoid malignancies after reduced-intensity conditioning regimen: similar outcomes with umbilical cord blood and unrelated donor peripheral blood

Alternative donor hematopoietic stem cell transplantation for mature lymphoid malignancies after reduced-intensity conditioning regimen: similar outcomes with umbilical cord blood and unrelated donor peripheral blood

... difference in HSCT procedures, conditioning regimens and GVHD prophylaxis between the two stem cell ...complex to carry out, given the heterogeneity of clinical settings and ... Voir le document complet

9

The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years—a report from the EBMT acute leukemia working party

The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years—a report from the EBMT acute leukemia working party

... donor to male recipient (p = 0.01). Secondary AML was more frequent in the 8/10 mM-URD group (44 versus <30 %, p = ...missing in 52 to 55 %, of the ...of patients were transplanted ... Voir le document complet

15

Outcomes following hematopoietic stem cell transplantation in patients treated with standard chemotherapy with or without gemtuzumab ozogamicin for acute myeloid leukemia

Outcomes following hematopoietic stem cell transplantation in patients treated with standard chemotherapy with or without gemtuzumab ozogamicin for acute myeloid leukemia

... CR in the GO ( n = 29) and control (n = 44) arms, respectively, median time from first CR to HSCT was ...occurred in three patients (GO: n = 2; control: n = 1; Table S2), for a rate of ... Voir le document complet

5

Preemptive cellular immunotherapy after T-cell-depleted allogeneic hematopoietic stem cell transplantation.

Preemptive cellular immunotherapy after T-cell-depleted allogeneic hematopoietic stem cell transplantation.

... Nonmyeloablative Stem Cell Transplantation Followed by Preemptive DLI Several studies have now shown that PBSC transplan- tation after a reduced-intensity nonmyeloablative condi- tioning ... Voir le document complet

9

Allogeneic hematopoietic stem cell transplantation (HSCT) after reduced intensity conditioning

Allogeneic hematopoietic stem cell transplantation (HSCT) after reduced intensity conditioning

... t Allogeneic hematopoietic stem cell transplantation (HSCT) following myeloablative (con- ventional) conditioning regimen is associated with a high incidence of ... Voir le document complet

7

Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation (HSCT)

Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation (HSCT)

... tological malignancies to graft-versus-tumour effects is supposed to be different (Figure ...274 patients with AML in first (n=160) or second (n=71) CR or with more ... Voir le document complet

7

Results from a clofarabine-busulfan-containing, reduced-toxicity conditioning regimen prior to allogeneic stem cell transplantation: the phase 2 prospective CLORIC trial

Results from a clofarabine-busulfan-containing, reduced-toxicity conditioning regimen prior to allogeneic stem cell transplantation: the phase 2 prospective CLORIC trial

... centers in France (Bordeaux, Lyon, Nantes, Marseille, Strasbourg and ...(AFSSAPS). Patients eligible for a RIC allogeneic SCT, aged between 18 and 65 years old, with high-risk MDS 19 not ... Voir le document complet

7

A prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation *

A prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation *

... Chronic Malignancies Working Party (CMWP) of the EBMT performed a large prospective, non-interven- tional study to evaluate prognostic pre-transplant fac- tors in MDS and chronic myelomonocytic ... Voir le document complet

13

Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia

Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia

... inferior outcome after alloSCT in ...contribute to this finding. First, characteristics associated with NRM ...donor to male patient, CMV seropositivity) had a high impact on OS ... Voir le document complet

10

Bendamustine-based conditioning prior to autologous stem cell transplantation (ASCT): Results of a French multicenter study of 474 patients from LYmphoma Study Association (LYSA) centers

Bendamustine-based conditioning prior to autologous stem cell transplantation (ASCT): Results of a French multicenter study of 474 patients from LYmphoma Study Association (LYSA) centers

... associated with ARF were identified through a univariate ...performed to identify the independent prognostic factor of ...formed with SPSS and SAS® version ... Voir le document complet

7

Thymic Recovery After Allogeneic Hematopoietic Cell Transplantation with Nonmyeloablative Conditioning Might Be Limited to Patients Younger Than 60 Years of Age.

Thymic Recovery After Allogeneic Hematopoietic Cell Transplantation with Nonmyeloablative Conditioning Might Be Limited to Patients Younger Than 60 Years of Age.

... according to patient age at ...100 to 1 and 2 years after transplantation in patients 50 (n=23; ...and in those 51-60 years of age (n=35; ...not in patients >60 ... Voir le document complet

2

Allogeneic peripheral blood stem cell transplantation with anti-thymocyte globulin versus allogeneic bone marrow transplantation without anti-thymocyte globulin

Allogeneic peripheral blood stem cell transplantation with anti-thymocyte globulin versus allogeneic bone marrow transplantation without anti-thymocyte globulin

... blood stem cells; AML: acute myeloid leukemia; ATG: anti-thymocyte globulin; HSCT: hematopoietic stem cell transplantation; IQR: interquartile range; CR: complete remission; CMV: ... Voir le document complet

10

Chimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

Chimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

... nonmyeloablative conditioning regimens followed by allogeneic HCT have been increasingly used in patients with hematologic diseases who are not considered candidates for conventional ... Voir le document complet

11

Comparison of thrombotic microangiopathy after allogeneic hematopoietic cell transplantation with high-dose or nonmyeloablative conditioning

Comparison of thrombotic microangiopathy after allogeneic hematopoietic cell transplantation with high-dose or nonmyeloablative conditioning

... Patients, conditioning regimen, and postgrafting immunosuppression Data from 287 patients given allogeneic bone marrow or peripheral blood stem cells after myeloablative or non- ... Voir le document complet

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