[PDF] Top 20 Progesterone receptor, obesity and prognosis in women diagnosed with estrogen receptor positive breast cancer
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Progesterone receptor, obesity and prognosis in women diagnosed with estrogen receptor positive breast cancer
... the positive but not significative associations or half of the studies contradicting the other half ...between obesity and prognosis among women with HR+ tumors, though it was ... Voir le document complet
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Prospective Clinical Utility Study of the Use of the 21-Gene Assay in Adjuvant Clinical Decision Making in Women With Estrogen Receptor-Positive Early Invasive Breast Cancer: Results From the SWITCH Study
... for estrogen receptor-positive (ER 1), early-stage breast cancer (EBC) in the adjuvant ...considerably in different countries according to various treatment ...assay ... Voir le document complet
7
Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer
... by Estrogen Receptor Alpha (erα) and Contributes to ER Signaling To investigate whether MAGI1 may be regulated by estrogen and ERα, we first analyzed bioinformatically the MAGI1 ... Voir le document complet
23
Reproductive factors and risk of hormone receptor positive and negative breast cancer: a cohort study.
... sign and large number of incident cases with receptor ...an in- depth analysis of reproductive-related relative risks, describing risk associations among women of predo- minantly ... Voir le document complet
13
Estrogen receptor signaling as a target for novel breast cancer therapeutics.: new targets in estradiol receptor-positive breast cancers
... 5 and do not respond to HT; in such cases the use of trastuzumab (Herceptin) a humanized monoclonal antibody targeting ErbB-2, has offered a considerable benefit, but a significant number of breast ... Voir le document complet
58
Dietary lignan intake and postmenopausal breast cancer risk by estrogen and progesterone receptor status.
... as in other observational studies, we cannot rule out that the associations we observed have resulted from confounding bias, although we adjusted the analyses for known risk factors of breast cancer, ... Voir le document complet
18
The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors
... ERα46 and ERα66 isoforms in the cellular responses induced by ...isoforms with 154 unique coregulator-derived motifs, both in their unliganded (apo) conformation or with concentra- ... Voir le document complet
17
View of Personal goals of women recently diagnosed with breast cancer: Protocol for a cohort study
... how women think or feel about their goals ...associated with important outcomes: higher goal importance may be associ- ated with better psychological outcomes among people liv- ing with ... Voir le document complet
8
Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma.
... (NAT1 and NAT2) physically linked in chromosomal region ...NAT1 and NAT2 enzymes have distinct substrate specificity, although they do share certain substrates such as aromatic and ... Voir le document complet
13
Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells.
... IGF1R in cells not exposed to ICI ...ments in which we knocked down Akt1 and Akt2 by targeting their shared nucleotide sequence demonstrated that the Akt protein is necessary for the full mitogenic ... Voir le document complet
15
Plasma estrogen levels, estrogen receptor gene variation, and ischemic arterial disease in postmenopausal women: the three-city prospective cohort study.
... estradiol, estrogen receptor gene variation and ischemic arterial disease in postmenopausal women: the Three-City prospective Cohort Study " submitted for publication as an original ... Voir le document complet
30
Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1
... panels with overlapping staining appearing in ...transfected with the PRE 2 -TATA- CAT reporter plasmid (2.5 g/ml) along with pSG5-rPR ...g/ml) and increasing amount of pSG5-HA vector ... Voir le document complet
10
Metabolic effect of estrogen receptor agonists on breast cancer cells in the presence or absence of carbonic anhydrase inhibitors
... concentrations in both MCF7 and MCF7HER2 cells in all treatments compared to MCF10A ...arginine and ethanol are consistently more concentrated in cancer cell ...lines. In ... Voir le document complet
16
The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene.
... E2 in normal epithelial cells compared to breast cancer ...cells. In this scenario, ERα triggers LRH1 expression, which, in turn, upregulates the expression of cyclins D1 promoting ... Voir le document complet
29
Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.
... on estrogen response element-dependent luciferase activity in HELN cells, transfected with estrogen receptor (ER) α or its mutants Effects of prenyltransferase inhibitors on ... Voir le document complet
12
Cytoplasmic and Nuclear Forms of Thyroid Hormone Receptor β1 Are Inversely Associated with Survival in Primary Breast Cancer
... hormone receptor β1 (THRβ1) by immunohistochemistry in breast cancer (BC) tissues and to correlate the results with clinico-biological ...parameters. In a ... Voir le document complet
15
O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH-Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells.
... of cancer growth and ...involved in the control of cell proliferation or cell death can be regulated by O- GlcNAc ...detected in cells derived from breast, lung, colon, liver and ... Voir le document complet
18
GWAS in the SIGNAL/PHARE clinical cohort restricts the association between the FGFR2 locus and estrogen receptor status to HER2-negative breast cancer patients
... structure in French breast cancer cases would influence imputation, while maximizing the proportion of the genome ...Backbone” and over 244000 ... Voir le document complet
19
Persistence of an intact endometrial matrix and vessels structure in women exposed to VA-2914, a selective progesterone receptor modulator.
... associated with a minimum of three months of chronic treatment with PRMs including VA-2914 were recently evaluated by a panel of ...dilatation and little evidence of mitosis, consistent with ... Voir le document complet
21
Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15.
... FOXA1 and AR-related genes (UGT2B28A, ALCAM, AGR2, SPDEF and TTF3) expression using spe- cific primers and probes or Gene Expression Assays (Applied Biosystems ...control and final results ... Voir le document complet
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