[PDF] Top 20 Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
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Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
... is the most important excitatory neurotransmitter in the mammalian ...brain. In the basal state, 60-75% of the total cortical glucose utilization corresponds to glutamatergic ... Voir le document complet
22
Mouse model for bilateral adrenal hyperplasia
... is a potential tumor suppressor gene [4] ...lethal in early mouse embryos [5] , adrenal-specific knockout was required to demonstrate tumor suppressor ...inactivation in ... Voir le document complet
2
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
... profiles in response to cisplatin compared to controls (Supp ...response in vivo is not dependent on the p53-p21 ...investigate the kinetics of cisplatin adduct formation and DNA damage ... Voir le document complet
37
Alterations of specific cortical GABAergic circuits underlie abnormal network activity in a mouse model of Down syndrome
... charge in Ts mice is likely due to one or a combination of different non-linearities that dynamically emerge during a spike ...include the recruitment of peri- or extrasynaptic GABA A ... Voir le document complet
24
Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
... consumption. In Hyal2 -/- mice, plasma levels of three typical endothelial cell injury markers, ...abnormalities in regula- tory elements of the complement cascade, deficiency in vWF-cleaving ... Voir le document complet
8
Obinutuzumab plus fludarabine and cyclophosphamide in previously untreated, fit patients with chronic lymphocytic leukemia: a subgroup analysis of the GREEN study
... ]. The discrepancy between the CR and MRD negativity rates in the present study is, however, currently ...unclear. In CLL10, the MRD negativity rate reported for fit CLL ... Voir le document complet
11
Investigation of the effect of lymphocytic microparticles on the activity of Müller cells in the oxygen-induced retinopathy mouse model
... qui a un rôle proangiogénique dans la ...LMP in vitro et in vivo. In vitro, l'influence des LMP sur les propriétés des cellules de Müller a été déterminée en utilisant des cellules de ... Voir le document complet
190
The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network.
... determination For each mouse, 5-HT- and TPH2-immunoreactive neurons were counted within the dorsal raphe (DR) and the median raphe nuclei (Bregma ...within the dorsal dentate gyrus ... Voir le document complet
17
Boceprevir for previously untreated patients with chronic hepatitis C Genotype 1 infection: a US-based cost-effectiveness modeling study.
... that the boceprevir-based treatment strategy offers great clinical benefit for the cost that is ...updates in the model structure and ...– a recently ap- proved protease ... Voir le document complet
18
Preventive Effect of Spontaneous Physical Activity on the Gut-Adipose Tissue in a Mouse Model That Mimics Crohn’s Disease Susceptibility
... counteract the effect of a Western diet [ 43 , 44 ...reduced in patients with CD [ 45 ]. The decrease of Lactobacillus and Bifidobacterium in the control group suggests that PA ... Voir le document complet
15
Cost-effectiveness model for sofosbuvir in chronic hepatitis C
... Amsterdam, The Netherlands ; November 8-12, 2014 Figure 1. Markov model schematic for chronic hepatitis C (CHC) § Although the model allows reporting of several types of ... Voir le document complet
1
Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer
... Abstract The epigenetic regulator BMI1 is upregulated progressively in a wide variety of human tumors including colorectal ...cancer. In this study, we assessed the requirement ... Voir le document complet
13
Detection of stop consonant voicing : toward a speaker independent model
... These cues include the time from the release to the onset of low-frequency amplitude (VOT for voiced consonants tend to be shorter in duration than for unvoiced consonants), [r] ... Voir le document complet
89
Operatively induced chronic reflux in rats: A suitable model for studying esophageal carcinogenesis?
... highlighted in the literature when comparing human observations with previous animal models, 1,5-10 including the devel- opment of benign tumor and adenosquamous tumors observed rarely in ... Voir le document complet
18
Chronic Exposure to Low Doses of Dioxin Promotes Liver Fibrosis Development in the C57BL/6J Diet-Induced Obesity Mouse Model
... study the combination of TCDD treatment and an obesogenic diet in mouse ...is the threshold dose that leads, after repeated exposure during 6 weeks, to the first signs of liver ... Voir le document complet
10
Complexin2 modulates working memory-related neural activity in patients with schizophrenia
... interpreted in light of the following ...be in high linkage disequilibrium with other functional variants that are responsible for the effects described ...models in European ... Voir le document complet
10
Interest of colchicine in the treatment of acute myocardial infarct responsible for heart failure in a mouse model
... colchicine in the treatment of acute myocardial infarct responsible for heart failure in a mouse model Mariama Akodad, ... Voir le document complet
8
Can We Extrapolate From a Cmah -/- Ldlr -/- Mouse Model a Susceptibility for Atherosclerosis in Humans?
... Soulillou a,b,1 , Emanuele Cozzi c , Cesare Galli d , and Jean-Marie Bach e We read with great interest the paper of Kawanishi et ...al. in PNAS (1). Humans lack a functional cytidine ... Voir le document complet
3
Activity server--a model for everday office activities
... The finger server returns the least idle time and hosts of all users; the location server returns the location of all users and the phone server returns the curre[r] ... Voir le document complet
83
Widespread distribution of beta-hexosaminidase activity in the brain of a Sandhoff mouse model after coinjection of adenoviral vector and mannitol
... into the rat brain. 13 The benefit of mannitol can be explained as a local osmotic effect accompanied by a shrinkage of the cells and an enlargement of the interstitial space, ... Voir le document complet
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