[PDF] Top 20 Common and rare variant analysis in early-onset bipolar disorder vulnerability.
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Common and rare variant analysis in early-onset bipolar disorder vulnerability.
... Abstract Bipolar disorder is one of the most common and devastating psychiatric disorders whose mechanisms remain largely ...twin and adoption studies, a polygenic background influences ... Voir le document complet
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A SNAP25 promoter variant is associated with early-onset bipolar disorder and a high expression level in brain.
... similar analysis taking into account the disease status (affected or unaffected) in a multivariate model, and showed that the influence of genotypes on the mRNA expression level of SNAP25b in ... Voir le document complet
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European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset.
... ABSTRACT Bipolar disorder has a genetic component, but the mode of inheritance remains ...conducted in 70 European families led to detect 8 regions linked to bipolar ...the disorder ... Voir le document complet
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An ASMT variant associated with bipolar disorder influences sleep and circadian rhythms: a pilot study.
... with bipolar disorder (BD) experience persistent circadian rhythm and sleep abnormalities during periods of remission, and biological studies have shown that these patients have abnormal ... Voir le document complet
22
A Multilevel Functional Study of a SNAP25 At-Risk Variant for Bipolar Disorder and Schizophrenia
... player in synaptic vesicle docking and fusion and has been associated with multiple psychiatric conditions, including schizophrenia, bipolar disorder, and ... Voir le document complet
9
Identification of shared risk loci and pathways for bipolar disorder and schizophrenia
... SNPs in our BD GWAS [ 12 ] were compared to those reported in the PGC SCZ ...patients and 46,839 controls. Our BD GWAS comprised data from 9,747 patients and 14,278 controls [ 12 ...patients ... Voir le document complet
14
Reduced white matter integrity in sibling pairs discordant for bipolar disorder.
... symptom onset; and is suggestive of molecular pathways putatively implicated in the disorder (4, ...10) and our observations of reductions in unaffected relatives and high ... Voir le document complet
18
Common vs. Distinct Visuomotor Control Deficits in Autism Spectrum Disorder and Schizophrenia
... load in schizophrenia (Biswas, Malhotra, Malhotra, & Gupta, 2007), as well as in autism spectrum disorder (Goldman et ...The common presence of NSS and shared multifactorial ... Voir le document complet
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A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans
... ALSPAC and TwinsUK data ...data and samples generated by the 1958 Birth Cohort ...Trust and Medical Research Council (grant numbers WT095219MA and ...institutional and personal ... Voir le document complet
11
View of Loopy: The Political Ontology of Bipolar Disorder
... above and noted by Massumi, this ‘long and ever-extending’ list, “combines an ontology with an epistemology in such a way as to endow itself with powers of ...self and others; one that is ... Voir le document complet
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Aripiprazole in patients with bipolar disorder: An update of practical guidance
... Lundbeck, and Sanofi ...lectures and/or served as a member of the advisory board of Bristol-Myers Squibb, AstraZeneca, ...lectures and/or served as a member of the advisory board of Bristol-Myers ... Voir le document complet
15
Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges
... stabilization and relapse ...symptoms and enhancing general function ( Geddes and Miklowitz, 2013; Goodwin et ...psychotropics and the ...retardation and akathisia, all of which may ... Voir le document complet
16
Thymus involvement in early-onset myasthenia gravis
... (ptosis and/or diplopia) and extends to other muscles in 80% of ...disease in which the target organ, the muscle, is distinct from the effector organ, the ...thymus. In MG patients with ... Voir le document complet
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Clinical expression of bipolar disorder type I as a function of age and polarity at onset: convergent findings in samples from France and the United States.
... optimal and best targeted drugs for treatment. Our findings and those of previous studies provide evidence that onset polarity should be considered as a relevant specifier in future BD1 ... Voir le document complet
21
Molecular characteristics of Human Endogenous Retrovirus type-W in schizophrenia and bipolar disorder.
... CONTROLS WITH NEGATIVE CRP (C-) TABLE S3: HERV-W RNA RELATIVE EXPRESSION AND DNA COPY NUMBERS STATISTICAL ANALYSES EXCLUDING BIPOLAR DISORDER PATIENTS TREATED WITH VALPROATE. ... Voir le document complet
18
Salmonella thyphimirium early onset neonatal sepsis
... stools; the National Reference Center identified a Salmonella Typhimuriu m. Cerebrospinal fluid culture remained sterile. Clinical and biological evolutions were rapidly favourable with 14-days of cefotaxim ... Voir le document complet
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Genetic contribution to the aggregation of schizophrenia and bipolar disorder in multiplex consanguineous Pakistani pedigrees
... rates and the negative selection acting against ...similar in different populations and they are not affected by genetic ...even in patient populations requires very large sample size for ... Voir le document complet
189
Is there a common motor dysregulation in sleepwalking and REM sleep behaviour disorder?
... diseases, and psychotropic drug ...participate in the context of their regular treatment routine after having read the information available in ... Voir le document complet
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Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder.
... Stefansson, H., Ophoff, R.A., Steinberg, S., Andreassen, O.A., Cichon, S., Rujescu, D., Werge, T., Pietilainen, O.P., Mors, O., Mortensen, P.B., Sigurdsson, E., Gustafsson, O., Nyegaard, M., Tuulio-Henriksson, A., ... Voir le document complet
19
Selves Impairment in Bipolar Disorder through Self-Concept Clarity, Self-Defining Memories and Self-Esteem
... past and future events ;it is marked out by chapters, key scenes, main characters, and ...intense and well-rehearsed autobiographical memories (AMs) that reflect the central themes of the ... Voir le document complet
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