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umbilical cord blood (UCB)

Alternative donor hematopoietic stem cell transplantation for mature lymphoid malignancies after reduced-intensity conditioning regimen: similar outcomes with umbilical cord blood and unrelated donor peripheral blood

Alternative donor hematopoietic stem cell transplantation for mature lymphoid malignancies after reduced-intensity conditioning regimen: similar outcomes with umbilical cord blood and unrelated donor peripheral blood

... The present study has several limitations, like all reg- istry-based retrospective analyses. As expected, there was a significant difference in HSCT procedures, conditioning regimens and GVHD prophylaxis between the two ...

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Expanded NK cells from umbilical cord blood and adult peripheral blood combined with daratumumab are effective against tumor cells from multiple myeloma patients

Expanded NK cells from umbilical cord blood and adult peripheral blood combined with daratumumab are effective against tumor cells from multiple myeloma patients

... 2. Results 2.1. Peripheral and umbilical cord blood NK expansion NK cells were expanded using two different protocols. UCB NK cells, due to their need for both KIR and KAR signals to reach a mature ...

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Chondrogenic commitment of human umbilical cord blood-derived mesenchymal stem cells in collagen matrices for cartilage engineering

Chondrogenic commitment of human umbilical cord blood-derived mesenchymal stem cells in collagen matrices for cartilage engineering

... 1,* Umbilical cord blood (UCB) is a promising alternative source of mesenchymal stem cells (MSCs), because UCB-MSCs are abundant and harvesting them is a painless non-invasive ...

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Engraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen

Engraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen

... Umbilical cord blood transplant recipients are exposed to an increased risk of graft failure, a complication leading to a higher rate of transplant-related ...single-unit umbilical cord ...

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Umbilical cord blood banking

Umbilical cord blood banking

... an umbilical cord blood transplant is very low in the general population, so that it is currently highly unlikely for a family with no history of blood disease or metabolic disorder to ever ...

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Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiolo

Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the EBMT

... of umbilical cord blood transplantation (CBT) in acute myeloid leukemia (AML) patients with active disease at allogeneic hematopoietic cell transplantation (allo-HCT) remains poorly ...

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Effect of HLA-matching recipients to donor non-inherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy

Effect of HLA-matching recipients to donor non-inherited maternal antigens on outcomes after mismatched umbilical cord blood transplantation for hematologic malignancy

... mismatched umbilical cord blood transplantation for hematologic malignancy Vanderson Rocha, MD, PhD Stephen Spellman, MS Mei-Jie Zhang, PhD Annalisa Ruggeri, MD Duncan Purtill, MD Colleen Brady, BS ...

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Reconstitution of adaptive immunity after umbilical cord blood transplantation and clinical implication regarding risk of infections

Reconstitution of adaptive immunity after umbilical cord blood transplantation and clinical implication regarding risk of infections

... peripheral blood is characterized by higher concentration of hematopoietic stem and progenitor cells than adult peripheral blood (61), each UCB unit contains about a 10–100-fold lower total cell dose ...

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Does pre-existing type 1 and type 2 diabetes during pregnancy lower docosahexaenoic acid and arachidonic acid in the umbilical cord blood of newborns and thus interfere with neurodevelopment?

Does pre-existing type 1 and type 2 diabetes during pregnancy lower docosahexaenoic acid and arachidonic acid in the umbilical cord blood of newborns and thus interfere with neurodevelopment?

... Th is absence of ev idence for impa ired neurodeve lopmen t in the neona tes from the d iabe t ic group occur red desp i te ev idence for lower AA trans fer f rom mo the r[r] ...

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H-1-NMR-Based Metabolic Profiling of Maternal and Umbilical Cord Blood Indicates Altered Materno-Foetal Nutrient Exchange in Preterm Infants

H-1-NMR-Based Metabolic Profiling of Maternal and Umbilical Cord Blood Indicates Altered Materno-Foetal Nutrient Exchange in Preterm Infants

... maternal blood, considered to reflect the presence of active transport systems within the placenta ...venous umbilical cord plasma from this mother–infant ...in cord plasma amino acid ...

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Sub-microscopic Plasmodium falciparum infections in matched peripheral, placental and umbilical cord blood samples from asymptomatic Congolese women at delivery

Sub-microscopic Plasmodium falciparum infections in matched peripheral, placental and umbilical cord blood samples from asymptomatic Congolese women at delivery

... Competing interests The authors declare that they have no competing interests. Acknowledgements We are highly indebted to all women who donated blood samples for this study. We are also sincerely grateful to the ...

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Cord Blood Glutathione Depletion in Preterm Infants: Correlation with Maternal Cysteine Depletion

Cord Blood Glutathione Depletion in Preterm Infants: Correlation with Maternal Cysteine Depletion

... venous umbilical cord blood, which likely represents the sum of the GSH distributed from the placenta into fetal circulation and GSH produced by fetal ...similar umbilical cord ...

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CD133 positive progenitor endothelial cell lines from human cord blood.

CD133 positive progenitor endothelial cell lines from human cord blood.

... Human umbilical cord blood Cord blood was collected from four normal, full-term deliveries at the Chair of Obstetrics and Gynecology of Wrocław Medical ...The umbilical vein was ...

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Natural killer cell licensing after double cord blood transplantation is driven by the self-HLA class I molecules from the dominant cord blood

Natural killer cell licensing after double cord blood transplantation is driven by the self-HLA class I molecules from the dominant cord blood

... no identifiable role in single-unit dominance following double-unit umbilical cord blood transplantation. Bone Marrow Transplant. 2015;50(1):150-152. 13. Foley B, Cooley S, Verneris MR, et al. NK ...

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Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia

Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia

... Introduction Allogeneic hematopoietic cell transplantation (allo- HCT) is commonly offered to patients with acute mye- loid leukemia (AML) as a curative treatment modality. The degree of human leukocyte antigen (HLA) ...

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Encephalitis caused by an unusual human herpes virus type 6 and Toxoplasma gondii co-infection in a cord blood transplant recipient

Encephalitis caused by an unusual human herpes virus type 6 and Toxoplasma gondii co-infection in a cord blood transplant recipient

... HHV-6 encephalitis appears to occur more frequently in patients undergoing CBT. 3 Some studies have suggested that the increased prevalence of HHV-6 reactivation may be due to the large number of immature T-cells present ...

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Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

... Results In vitro cell characterization Measures of ICC for both low- and high-passage UC MSCs showed positive expression of SCA1, a marker of mouse MSCs (Figure 1). Flow cytometry revealed that low-passage UC MSCs ...

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Umbilical cord-derived mesenchymal stromal cells: predictive obstetric factors for cell proliferation and chondrogenic differentiation

Umbilical cord-derived mesenchymal stromal cells: predictive obstetric factors for cell proliferation and chondrogenic differentiation

... Cell and tissue engineering protocols require large amounts of cells [35], and, as highly proliferative cells, WJ-MSC are a crucial alternative to BM-MSC. Indeed, their collection is painless, non-invasive and more pro- ...

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Scarless cholecystectomy: laparoscopic surgery by unique umbilical incision

Scarless cholecystectomy: laparoscopic surgery by unique umbilical incision

... La chirurgie assis- tée par robot (par exemple le robot Da Vinci) est loin d’avoir démontré un quelconque avantage, particulièrement en chirurgie abdominale, tout en étant [r] ...

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