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Obesity and type 2

Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes

Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes

... epidemics, type 2 diabetes (T2DM) and obesity, is associated with increased mortality and morbidity and represents one of the most important public health challenges worldwide 1 ...

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Oxidative Stress and Obesity- and Type 2 Diabetes-Induced Heart Failure

Oxidative Stress and Obesity- and Type 2 Diabetes-Induced Heart Failure

... Activity and Central Obesity in Patients with Type 2 Diabetes at High Risk of Cardio-Renal ...Oxidase 2 Mediates Myocardial Oxygen Wasting in ...

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Longitudinal monitoring of cardiac dysfunction with MRI in a mouse model of obesity and type 2 diabetes

Longitudinal monitoring of cardiac dysfunction with MRI in a mouse model of obesity and type 2 diabetes

... include type 2 diabetes and cardi- ovascular ...heart and liver, have recently been shown to be important independent risk factors for the development of these ...increase and insulin ...

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T Cell Populations and Functions Are Altered in Human Obesity and Type 2 Diabetes

T Cell Populations and Functions Are Altered in Human Obesity and Type 2 Diabetes

... the obesity epidemic, the diabetes epidemic has dramatically increased ...with obesity predisposes individuals to the development of type 2 diabetes ...Additionally, obesity and ...

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Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.

... age and sex reported on the tables of Rolland- Cachera et ...hood Obesity Group (ECOG) ...Adult obesity association studies were performed using two sets of adult obese patients: the first ...

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Skeletal muscle lipase content and activity in obesity and type 2 diabetes.

Skeletal muscle lipase content and activity in obesity and type 2 diabetes.

... freeze-dried and dissected free of all visible adipose tissue, connective tissue, and blood under a microscope and was subsequently homogenized (1:80 by volume), as de- scribed previously ...

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en fr Mucosal Associated Invariant T (MAIT) cells induce inflammation, gut dysbiosis, and type 2 diabetes during obesity Les lymphocytes MAIT induisent l'inflammation, la dysbiose et le diabète de type 2 au cours de l'obésité

... 30 CXCR2 a été décrit comme ayant un rôle potentiel dans le recrutement des macrophages dans le TA (Chavey et al., 2009; Nara et al., 2007; Neels et al., 2009). Chez les souris maigres les macrophages sont de petite ...

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Pathophysiology of type 2 diabetes.

Pathophysiology of type 2 diabetes.

... to obesity, but more importantly to differences in body fat distribution ...of type 2 diabetic patients are over- weight, and obesity undoubtedly plays a major role in the development ...

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Protein, amino acids and obesity treatment

Protein, amino acids and obesity treatment

... loss and improved lipid plasmatic profiles as well as mean blood pressure parameters, with a lesser effect when patients were already vegan or veg- etarian at baseline [ 38 ...obese and overweight adults ...

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Job strain as a risk factor for type 2 diabetes: a pooled analysis of 124,808 men and women.: Job Strain and Incident Type 2 Diabetes

Job strain as a risk factor for type 2 diabetes: a pooled analysis of 124,808 men and women.: Job Strain and Incident Type 2 Diabetes

... bias), and inclusion of well characterized cohort studies (facilitating an assessment of the independent effects of ...of type 2 diabetes varied between the ...diagnosed and undiagnosed ...

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Acarbose for type 2 diabetes prevention.

Acarbose for type 2 diabetes prevention.

... function and protection from type 2 diabetes persisted 8 months after interruption of troglitazone in the recent TRIPOD trial, 5 a finding that suggests a long-lasting protection effect with ...of ...

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Quelles propositions thérapeutiques pour le diabétique de type 2 de demain ?

Quelles propositions thérapeutiques pour le diabétique de type 2 de demain ?

... Ils sont recommandés par la HAS en bi et trithérapie en association à la metformine et/ou un sulfamide hypoglycémiant lorsque ces traitements ne sont pas suffisamment actifs aux doses maximales tolérées. L’association à ...

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Pharmacological prevention of type 2 diabetes.

Pharmacological prevention of type 2 diabetes.

... effects and peripheral metabolic effects in adipose tissue, liver, skeletal muscle and pancreas ...loss and waist circumference reduction, the latter being a key marker of intra-abdominal adiposity, ...

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Approches pharmacologiques de prévention du diabète de type 2.

Approches pharmacologiques de prévention du diabète de type 2.

... de type 2 mérite donc certainement confirmation, comme, par exemple, dans l'étude PROSPER actuellement en cours (Prospective Study of Pravastatin in the ...

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Localisation et ciblage de la protéase de l'adénovirus de type 2

Localisation et ciblage de la protéase de l'adénovirus de type 2

... Nous avons confirmé par des essais enzymatiques impliquant des extraits nucléaires et cytoplasmiques dans des réactions en Cis (résultats non-montrés) et en Trans (en [r] ...

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Generalized $N$ = 1 and $N$ = 2 structures in M-theory and type II orientifolds

Generalized $N$ = 1 and $N$ = 2 structures in M-theory and type II orientifolds

... complex, and real and imaginary part of each spinor, if they are never parallel, already define an SU(6) structure, so in general we would have “SU(6) × SU(6)” structures (and secretly, a theory with ...

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Polymorphic Functions with Set-Theoretic Types. Part 2: Local Type Inference and Type Reconstruction

Polymorphic Functions with Set-Theoretic Types. Part 2: Local Type Inference and Type Reconstruction

... of type unification: finding a proper substitution that makes the type of the domain of a function compatible with (ie, a supertype of) the type of the argument it is applied ...Our type uni- ...

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Emergence of a new type of porcine circovirus (PCV) in swine: a type 1 and type 2 PCV recombinant

Emergence of a new type of porcine circovirus (PCV) in swine: a type 1 and type 2 PCV recombinant

... Specific PCR assay results of the detection of the ORF1 gene of PCV1 and 351. the ORF2 gene of PCV2[r] ...

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Spinocerebellar ataxia type 2 (SCA2): clinical features and genetic analysis.

Spinocerebellar ataxia type 2 (SCA2): clinical features and genetic analysis.

... history and the pedigree revealed that 14 subjects over four generations were affected by the disease ...trait, and approximately one-half of the offspring were ...years and almost all cases followed ...

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Vitamin D and type 2 diabetes mellitus: Where do we stand?

Vitamin D and type 2 diabetes mellitus: Where do we stand?

... hyperaemia and sublingual glyceryl trinitrate) in T2DM patients [43] ...raising and maintaining serum VTD levels, although this is still a subject of ...

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