Microtubule associated protein
Role of the microtubule-associated protein ATIP3 in cell migration and breast cancer metastasis
... Abstract Microtubule-associated protein ATIP3 is the major product of candidate tumor suppressor MTUS1 gene down-regulated in breast ...potent microtubule stabilizer whose depletion increases ...
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The Drosophila Toucan protein is a new mitotic microtubule-associated protein required for spindle microtubule stability.
... Toucan protein interacts directly with ...the microtubule network when it is expressed in mammalian cells and its direct interaction with microtubules in vitro are dependent on its central basic ...a ...
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Expression of the microtubule-associated protein MAP9/ASAP and its partners AURKA and PLK1 in colorectal and breast cancers
... Background. Colorectal and breast cancers are among the most common cancers worldwide. They result from a conjugated deficiency of gene maintenance and cell cycle control. Objective. We investigate the expression of the ...
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Kinetic analysis of tubulin assembly in the presence of the microtubule-associated protein TOGp.
... The microtubule-associated protein TOGp which belongs to a widely distributed protein family from yeasts to humans, is highly expressed in human tumors and brain ...at microtubule ends ...
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Deletion of the microtubule-associated protein 6 (MAP6) results in skeletal muscle dysfunction
... Promote Microtubule Stabilization during Neuronal ...A. Microtubule- associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal ...
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Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth
... coronal T2-weighted images from wild-type (WT) and MAP6-KO mice were used to quantify the whole brain volume (Fig. 1a). Adult MAP6-KO mice from each genetic background showed reduced brain volume: 14% in homogeneous ...
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
... Tau protein present in the central nervous system (ranging from 352 to 441 amino acid residues), resulting from mRNA alternative splicing of a single gene ( Goedert et ...or microtubule binding region ...
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HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy
... the inhibition of the formation of the autophagosomes after binding to LC3 [53, 54]. This also explains why autophagy is uncontrolled in bystander CD4 T cells after their contact with HIV-1- infected cells. Indeed, in ...
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A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
... (microtubule associated proteins) including MAP1B, MAP2, Tau and MAP6 are attractive candi- dates in this ...controlling microtubule properties, MAPs have been recently shown to interact with actin ...
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Negative regulation of EB1 turnover at microtubule plus ends by interaction with microtubule-associated protein ATIP3
... TIRF microscopy for in vitro studies Perfusion chambers were functionalized with silane-PEG-biotin (Laysanbio) coverslips and silane-PEG (Creative PEGwork) glass slides as described [36]. The flow cell was firstly ...
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Non-Microtubular Localizations of Microtubule-Associated Protein 6 (MAP6)
... domain-containing protein 1, also called STOP-Like protein 21 kD, or SL21), bind to and stabilize ...is associated with synaptic defects, suggesting that MAP6s may also have alternative cellular ...
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Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II.
... and microtubule- stabilizing sequences ...mice, microtubule cold stability is suppressed, with no dramatic consequences for mouse organogenesis, viability or brain ...are associated with depleted ...
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Atypical, non-standard functions of the microtubule associated Tau protein
... retardation protein; FTDP-17: Frontotemporal dementia with parkinsonism linked to chromosome 17; FUS: RNA-binding protein fused sarcoma; G3BP1: GTPase-activating protein-bindingprotein 1; GluN: ...
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WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity
... the microtubule associated protein FAP20 ( Khalifa et ...POC16/WDR90-DUF667 protein orthologs (related to Figure 2—figure supplement 1A, B ...the microtubule-pelleting ...the ...
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The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network.
... of microtubule-associated protein stable tubule only polypeptide (STOP) leads to neuroanatomical, bio- chemical and severe behavioral alterations in mice, partly alleviated by ...between ...
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New surfactant protein C gene mutations associated with diffuse lung disease
... variants associated with respiratory diseases occurring during the first months of ...phenotype associated with I73T was described as eminently variable, ranging from fatal cases to asymptomatic adult ...
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Régulation de l'apoptose des lymphocytes T par GIMAP5 (GTPase of Immune Associated Nucleotide Binding Protein 5)
... nucleotide-binding protein 5) gene, resulting in a truncated protein lacking 223 amino acids at the C-terminus that are replaced by 19 other residues ...overexpressed protein with intact C-terminus ...
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Is the LIM-domain Protein HaWLIM1 Associated with Cortical Microtubules in Sunflower Protoplasts?
... CRP3/MLP protein (Kong et al., 1997). Furthermore, in tobacco, the LIM protein NtLIM1, an HaWLIM1 homolog which is involved in lignin biosynthesis, has been shown to transiently activate the transcription ...
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Lattice defects induce microtubule self-renewal
... in microtubule bundles or at intersections between two microtubules 13,14 ...that microtubule severing enzymes, such as spastin and katanin, are able to actively remove tubulin dimers from the ...a ...
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Time-course changes of muscle protein synthesis associated with obesity-induced lipotoxicity
... In the present study, modifications in muscles suggest that prolonged obesity has a negative impact on skeletal muscle mass by arresting the initial ‘anabolic’ action of the diet-induced obesity, but the mechanisms ...
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