Mice models
en fr Subsets monocytes study in obesity and insulin resistance in mice models Etude du rôle des sous-populations monocytaires dans l'obésité et l'insulinorésistance
... generated mice BM chimeras by reconstructing lethally irradiated C57BL/6 mice with BM cells isolated from 3 groups of mice with the following phenotype: i) CX3CR1 KI ii) CD11c- hBcl2/CX3CR1 KI and ...
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In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer
... in mice models of ...in mice and VCAM-1 expression was assessed in vivo by single-photon emission computed tomography (SPECT) imaging using 99m ...in mice and VCAM-1 expression in lung ...
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Cell replacement therapy for Huntington's disease : what we have learned from post-mortem analyses of grafted patients and mice models
... n=18 mice per experimental group) (Figure ...implantation, mice were anesthetized with ...CT). Mice were removed from the stereotactic apparatus and put back in their home cage for ...All mice ...
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β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models
... PK Controls Pink-1 Transcription in a PS-Dependent and PTEN-Independent Pathway We previously demonstrated that besides its well-characterized ubiquitin-ligase activity (44) , PK also behaved as a transcription factor ...
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Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures
... In the present study, sub-convulsive dose of pentylenete- trazole, when given intraperitoneally, on alternate days in- duced kindling in the vehicle-treated mice. The groups which were administered IGEFA showed ...
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3D visualization and quantification of bone and teeth mineralization for the study of osteo/dentinogenesis in mice models
... Fig 8: Comparison of 2D slices across the mandible using scanning microscopy (left) and micro-CT (right). Micro-CT images allowed precise visualization of hypomineralized areas in KOFM slices, rivalizing with scanning ...
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Jaw osteosarcoma models in mice: first description
... OS mice models have been developed in the long bones [ 19 ...mouse models refer to DNA damage studies [ 2 , 13 ], while genetically engineered mouse (GEM) models have been induced by deletion ...
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Spleen iron, molybdenum, and manganese concentrations are coregulated in hepcidin-deficient and secondary iron overload models in mice
... 3 Abstract Iron excess increases the hepatic expression of hepcidin, the systemic iron metabolism regulator, that favors the iron sequestration in the spleen. Genetic iron overload related to hepcidin insufficiency ...
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The Genotoxin Colibactin Shapes Gut Microbiota in Mice
... to mice which received the nongenotoxic ...in mice, the bacterial genotoxin colibactin may exert its activity even against the gut microbiota, beyond its known effects on the host (7, ...
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Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice
... deficient mice (ob/ob mice), Claycombe et ...transgenic mice carrying a C/EBP dominant negative transgene that induces deletion of mature adipocytes, showed improved marrow engraftment after ...
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Study of Leishmania pathogenesis in mice : experimental considerations
... in mice are regulated by genetic determinants ...In mice harboring wild type Scl11a1, such as the CBA mouse strain, parasite proliferation in liver is ...in mice with mutant Scl11a1, such as the ...
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Durable and controlled depletion of neutrophils in mice
... C57BL/6) mice 24 whose neu- trophils can be specifically identified based on tdTomato expres- sion, however SSCa lacks specificity (Supplementary ...treated mice despite adequate labelling, we asked whether ...
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Inulin attenuates atherosclerosis in apolipoprotein E-deficient mice
... All mice were fed a powdered purified diet, based on the AIN-93G recommendations, in which all carbohydrates were supplied as sucrose (Table ...age, mice were divided into four groups (eight mice per ...
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Effect of lyophilized prune extract on hyperhomocysteinemia in mice
... Publisher Pergamon Description Altered homocysteine metabolism defined as hyperhomocysteinemia is implicated as pathogenic factor in several cardiovascular diseases and atherosclerosis. The purpose of this study was to ...
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Ebola virus dynamics in mice treated with favipiravir
... infected mice lacked a type-I IFN response, which is a critical component of the immune response against systemic viral infections (Mohamadzadeh et ...other models) or is mostly the result of the viral ...
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Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice
... Found at: doi:10.1371/journal.pone.0002769.s004 (0.05 MB TIF) Acknowledgments The authors acknowledge Veronique Megrasa and Catherine Martinet for FACS analysis, Regine Paris, Jean-Baptiste Huguet and Coralie Pierre- ...
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Adult hematopoietic progenitors are pluripotent in chimeric mice
... chimeric mice and from four wildtype CD34+ control chimeric mice were stained with X-‐gal to determine if the cells of any organs of the chimeric mice were derived from the adult ROSA CD34+ cells ...
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Animal models
... For the publisher’s version, please access the DOI link below./ Pour consulter la version de l’éditeur, utilisez le lien DOI ci-dessous. https://doi.org/10.1258/0007142001903238 Access and use of this website and the ...
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Biodistribution of Novel 68Ga-Radiolabelled HER2 Aptamers in Mice
... Mouse model We developed a mouse model bearing a different tumour (i.e. one HER2-positive and one HER2-negative tumour) at each flank. This approach provides an ideal negative control and enables easy comparison between ...
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SCD1 deficiency protects mice against ethanol-induced liver injury
... protects mice from ethanol feeding-induced liver injury The chronic + binge protocol was used to induce AFLD and mouse livers were dissected for ...control mice, Scd1 KO: Scd1 knockout mice, EtOH: ...
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