MEMBRANE CHOLESTEROL
Clathrin-dependent APP endocytosis and Aβ secretion are highly sensitive to the level of plasma membrane cholesterol
... between cholesterol and Alzheimer's disease pathogenesis. Membrane cholesterol is known to modulate amyloid precursor protein (APP) endocytosis and amyloid-β (Aβ) ...that cholesterol exerts ...
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LXR regulate cholesterol homeostasis in the proximal mouse epididymis.
... of cholesterol and/or fatty ...specific membrane cholesterol trans- porter, ATP-binding cassette A1 (ABCA1) in the caput epididymidis of LXR-/- ...the cholesterol trafficking pathways in the ...
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Epididymis cholesterol homeostasis and sperm fertilizing ability
... PLASMA MEMBRANE CHOLESTEROL MATURATION: HYPOTHESES AND MODELS Even if it is well admitted that sperm plasma membrane cholesterol content changes during epididymal maturation of most mammalian ...
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Lipid rafts: dream or reality for cholesterol transporters?
... endogenous cholesterol becomes less accessible to the exogenously added soluble enzyme cholesterol oxidase also in an ATP-dependent manner (Garrigues et ...translocates membrane cholesterol ...
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Cholesterol: A Gatekeeper of Male Fertility?
... plasma membrane. Cholesterol is the most abundant sterol found in the spermatic membrane of many species ( 102 ...in cholesterol within the seminiferous ...novo cholesterol to allow the ...
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Cholesterol impacts chemokine CCR5 receptor ligand binding activity
... that cholesterol could play an important role in the process of viral fusion and CCR5 ...requires membrane cholesterol to retain ligand binding and signaling functions and for HIV virion entry into ...
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Cholesterol uptake and hepatitis C virus entry.
... triglycerides, cholesterol, and several apolipoproteins [1, ...on membrane cholesterol content and fusion of HCV pseudoparticles (HCVpp) with liposomes is enhanced by cholesterol enrichment of ...
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Prevention cardio-vasculaire par les statines: faut-il encore doser le cholesterol?
... FOR CHOLESTEROL MEASUREMENT ? SUMMARY : Statins, the most popular lipid-lowering agents, have proven their efficacy in preventing cardiovascular events in subjects with lower and lower initial plasma ...
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Partial area of cholesterol in monounsaturated diacylphosphatidylcholine bilayers
... of cholesterol and diCn:1PC in the sample, respec- ...of cholesterol present in the lipid bilayer. It is obvious that cholesterol causes increase in the bilayer thickness for all studied ...of ...
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Dietary Cholesterol and Lipid Overload: Impact on Male Fertility
... dietary cholesterol has a very negative impact on the reproductive function of male mice and rats, in accordance with the data obtained on ...dietary cholesterol and semen charac- teristics is di fficult to ...
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The crystal structure of cholesterol helical ribbons
... The top, left half of the image has been covered with boxes indicating the pattern pre- dicted by the unit cell obtained for helical ribbons in CDLC taken out of [r] ...
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LDL Cholesterol: ‘The Times They Are A-Changin’
... lipoprotein cholesterol concentrations subsequent to their separation by vertical spin density-gradient ultracentrifugation (VAP) rather than β- quantification; the VAP procedure is susceptible to underestimation ...
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Regulation of cholesterol intake by the corpus luteum
... is cholesterol, derived from multiple ...produce cholesterol de novo, this method plays a minor role in the normal functioning tissue as evidenced by the low levels of 3- hydroxy-3-methylglutaryl coenzyme ...
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TECHNICAL CHALLENGES IN CHOLESTEROL REMOVAL FROM DAIRY PRODUCTS
... of cholesterol in membrane can be studied by: ...of cholesterol removal on suface properties – Interfacial measurements, Study of monolayers, Interfacial rheology, Zeta ...
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Phytosterol ester processing in the small intestine: impact on cholesterol availability for absorption and chylomicron cholesterol incorporation in healthy humans
... intestinal cholesterol absorption, but the complex dynamics of the lipid digestion process in the presence of phytosterol esters (PEs) are not fully ...contrast, cholesterol accumulation in the duodenum ...
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Determining Cholesterol Binding to Membrane Proteins by Cholesterol 13C Labeling in Yeast and Dynamic Nuclear Polarization NMR
... show cholesterol ring orientations that differ substantially from the rest of the ensemble ...M2-bound cholesterol, despite the good RSS ...Two cholesterol molecules are docked onto the four-helix ...
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Hydrogen Bonding of Cholesterol in the Lipidic Cubic Phase
... for membrane protein crystallization can be rationalized by the ability of this phase to provide a stabilizing membrane-like environment for membrane proteins and to support type I crystal ...the ...
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Processing of oat: the impact on oat's cholesterol lowering effect
... As discussed above, purified forms of β-glucan were found to be less successful at inducing changes in blood lipids 56,86,98,99,101 than intact oat tissues. 23,152 This is consist- ent with epidemiology studies showing ...
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The hedgehog receptor patched is involved in cholesterol transport.
... Cholesterol Transport Michel Bidet 1 , Olivier Joubert 1,2 , Benoit Lacombe 1 , Marine Ciantar 1 , Rony Nehme´ 1,3 , Patrick Mollat 4 , Lionel Bre´tillon 5 , He´le`ne Faure 6 , Robert Bittman 7 , Martial Ruat 6 , ...
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A new perspective on the development of cholesterol-lowering products
... blood cholesterol and postprandial blood glucose [ ...hepatic cholesterol and lipoprotein metabolism, also resulting in lowering of plasma LDL cholesterol [ ...of cholesterol- - -hydroxylase, ...
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