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high-grade glioma treatment

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

Combining the DNA Repair Inhibitor Dbait With Radiotherapy for the Treatment of High Grade Glioma: Efficacy and Protein Biomarkers of Resistance in Preclinical Models

... to treatment and could modify therapy ...bearing glioma CDX obtained by grafting the cell lines characterized in ...vivo treatment efficiency ...of high grade glioma ( 32 ), 6 ...

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MRI assessment of treatment delivery for interstitial photodynamic therapy of high-grade glioma in a preclinical model

MRI assessment of treatment delivery for interstitial photodynamic therapy of high-grade glioma in a preclinical model

... A significant difference in the distribution of Δd was found among the 3 groups, with an orderly increase from the sham to the 2-fraction and 5-fraction groups, (p < 0.01). In the sham group, the values remained ...

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Objective neurocognitive functioning and neurocognitive complaints in patients with high-grade glioma: Evidence of cognitive awareness from the European Organisation for Research and Treatment of Cancer brain tumour clinical trials

Objective neurocognitive functioning and neurocognitive complaints in patients with high-grade glioma: Evidence of cognitive awareness from the European Organisation for Research and Treatment of Cancer brain tumour clinical trials

... Methods: NCF was assessed using an internationally accepted clinical trial battery. NCC was assessed using the cognitive functioning questionnaire from the Medical Outcome Study (MOS) and the European Organisation for ...

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A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI

A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI

... a high signal on T2-weighted ...first treatment was a ventriculocysternostomy followed, fif- teen months later, by a partial resection when the lesion increased in ...a grade II oligodendroglioma ...

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The Subventricular Zone, a Hideout for Adult and Pediatric High-Grade Glioma Stem Cells

The Subventricular Zone, a Hideout for Adult and Pediatric High-Grade Glioma Stem Cells

... by high expression of the anti-apoptotic proteins Bcl2 and Mcl1 ( 94 ...of high levels of CXCL12 in the SVZ ( 95 ...the treatment of GBM ( 23 ...

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Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma

Predictive biomarkers of resistance to hypofractionated radiotherapy in high grade glioma

... EGFR, which was highly correlated to tumor response in our study has been found overexpressed in about 40% of glioblastomas [53] with approximately 50% of tumors with EGFR amplification carrying a specific EGFR mutant ...

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Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival

Ultrasmall theranostic gadolinium-based nanoparticles improve high-grade rat glioma survival

... a glioma model. The 9L glioma cells were orthotopically implanted in 10-week-old Fischer ...in high grade glioma, as well as the potential survival benefits when combined with ...

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Curling of concrete slabs on grade

Curling of concrete slabs on grade

... ratio, high-range water- reducing admixtures, largest-sized aggregate possible, and maximum volume of graded coarse aggregate possible per unit volume of concrete keeps water content ...

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High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor.

High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor.

... To our knowledge, a single study considered EREG ex- pression in glioma [21]. Previously, we showed that in- hibition of the Unfolded Protein Response (UPR) sensor IRE1α (also named ERN1) down-regulated the ...

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Biodiversity as a barrier to glioma cell invasion.

Biodiversity as a barrier to glioma cell invasion.

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ...

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Using binder-treatment technology for high-performance steel powder mixes

Using binder-treatment technology for high-performance steel powder mixes

... Figure 14 shows the compacting pressure and green strength obtained at 6.8 and 7.0 g/cm³ for two different mix formulations. 0.65% EBS wax was used in all cases. Compaction of rectangular bars of 31.7mm-12.7mm-6.4mm was ...

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Development and characterization of a bio-based epoxy matrix for high-grade bio-based composites

Development and characterization of a bio-based epoxy matrix for high-grade bio-based composites

... Abstract This study aims to develop 100% bio-based hemp/epoxy composites for semi-structural and structural applications. The thermal and mechanical performances of a 100% bio-based matrix derived from biomass are ...

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CONSONORM_HG: a new method of norm calculation for mid- to
high-grade metamorphic rocks

CONSONORM_HG: a new method of norm calculation for mid- to high-grade metamorphic rocks

... at high grade, alteration indices for amphibolite to granulite facies rocks need to be ...calculating high grade mineral assemblages is that normative minerals can be compared to minerals ...

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MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study

MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study

... Among the potential causes of progressive axonal degeneration in progressive MS are chronic demyelination and mitochondrial dysfunction, which both lead to a state of virtual hypoxia [ 4 – 6 ]. We recently reported the ...

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Efficacy of intracerebral delivery of Carboplatin in combination with photon irradiation for treatment of F98 glioma-bearing rats.: Efficacy of radiotherapy combined with prolonged i.c. delivery of carboplatin against F98 rat-glioma

Efficacy of intracerebral delivery of Carboplatin in combination with photon irradiation for treatment of F98 glioma-bearing rats.: Efficacy of radiotherapy combined with prolonged i.c. delivery of carboplatin against F98 rat-glioma

... limited, by their systemic toxicity, but also by their poor ability to penetrate an intact blood- brain barrier (BBB) in areas where there are microinvasive deposits of tumor (9). Several approaches have been proposed ...

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Functional Mapping before and after Low-Grade Glioma Surgery: A New Way to Decipher Various Spatiotemporal Patterns of Individual Neuroplastic Potential in Brain Tumor Patients

Functional Mapping before and after Low-Grade Glioma Surgery: A New Way to Decipher Various Spatiotemporal Patterns of Individual Neuroplastic Potential in Brain Tumor Patients

... the glioma, within the precentral sulcus (white ...(right) glioma resection, delineated by letter ...extensive glioma resection posteriorly, with no permanent ...the glioma involving the ...

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Effect of high-pressure treatment on denaturation of bovine lactoferrin and lactoperoxidase

Effect of high-pressure treatment on denaturation of bovine lactoferrin and lactoperoxidase

... processing. High-pressure treatment is an appealing alternative to the traditional heat processing of foods because it exerts an antimicrobial effect without changing the sensory and nutritional quality of ...

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Conditional Probability of Survival and Prognostic Factors in Long-Term Survivors of High-Grade Serous Ovarian Cancer

Conditional Probability of Survival and Prognostic Factors in Long-Term Survivors of High-Grade Serous Ovarian Cancer

... Keywords: high-grade serous ovarian cancer; conditional probability of survival; long-term survival; prognostic factors ...Introduction High-grade serous ovarian cancers (HGSOC) are ...

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Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

... We decided to investigate whether DNA damage-inducible transcript 4 (DDIT4) affects VV replication and we showed, using gain- and loss-of function studies that this is the case ( Fig 6B and 6C ). DDIT4 is expressed in ...

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Glioma resection and tumor recurrence : back to Semmelweis.

Glioma resection and tumor recurrence : back to Semmelweis.

... regards glioma recurrence at the resection margin, accumulative evidence suggests that the tissue response to SBI participates in the formation of recurrence-prone ...in glioma recurrence. To establish ...

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