Circulating tumor cells (CTC)
Diagnostic and prognostic value of circulating tumor cells in head and neck squamous cell carcinoma: a systematic review and meta-analysis
... detect circulating tumor cells (CTC) in patients with head and neck squamous cell carcinoma (HNSCC), but their diagnostic and prognostic value are not yet fully ...
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“Sentinel” Circulating Tumor Cells Allow Early Diagnosis of Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease
... Abstract Chronic obstructive pulmonary disease (COPD) is a risk factor for lung cancer. Migration of circulating tumor cells (CTCs) into the blood stream is an early event that occurs during ...
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eTumorType, an algorithm of discriminating cancer types for circulating tumor cells or cell-free DNAs in blood
... capturing circulating tumor cells (CTCs) and cell-free DNAs (cfDNAs) in blood, serum, and plasma [1–3] ...blood cells [4] , resulting in the generation of false negatives, false positives, or ...
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Circulating Antibodies to ALK Inversely Correlat with Relapse Risk and Circulating Tumor Cells in Children and Adolescents with ALK-Positive Anaplastic Large Cell Lymphoma
... 2008 Circulating Antibodies to ALK Inversely Correlat with Relapse Risk and Circulating Tumor Cells in Children and Adolescents with ALK-Positive Anaplastic Large Cell Lymphoma ...
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Circulating Tumor Cells and Circulating Tumor DNA Detection in Potentially Resectable Metastatic Colorectal Cancer: A Prospective Ancillary Study to the Unicancer Prodige-14 Trial
... Keywords: circulating tumor cells; circulating tumor DNA; liquid biopsy; metastatic colorectal cancer; FOLFIRINOX 1. Introduction While most patients diagnosed with metastatic ...
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Acoustic separation of circulating tumor cells
... Circulating tumor cells (CTCs) are important targets for cancer biology ...rare tumor cells from peripheral blood must be ...biological cells using label-free and contact- free ...
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Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment
... Keywords: circulating tumor cells; hematological cells; neutrophils; platelets; liquid biopsy ...Introduction Circulating tumor cells (CTCs) have been extensively studied ...
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Biodegradable nano-films for capture and non-invasive release of circulating tumor cells
... of circulating tumor cells (CTCs) from whole blood is an important capability for both clinical medicine and biological ...isolated cells under excessive stresses that reduce cell viability, ...
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EMT-Associated Heterogeneity in Circulating Tumor Cells: Sticky Friends on the Road to Metastasis
... including tumor cell migration or CTC survival [ 68 ...Cancer-Stem Cells (CSCs) [ 94 , 95 ], it is important to note that EMT induces the expression of stem cell attributes [ 96 , 97 ] and that certain EMT ...
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Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials.
... SWOG 0500 (USA) Rationale: As stated above, several observational studies support the fact that CTC changes during the weeks following the first cycle of chemotherapy is associated with PFS and OS (1). This observation ...
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Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells.
... to CTC, the expression of EMT mediators has been detected in CTCs in animal models (2, 10) and in subpopulations of CTCs isolated from cancer patients including breast cancer patients, where they associate with poor ...
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Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery
... to tumor invasion and ...malignant cells by either cytological features or by antigen detection using immunofluorescence or ...of cells with an epithelial phenotype thereby permitting the use of CTCs ...
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Combination of mechanical and molecular filtration for enhanced enrichment of circulating tumor cells
... more cells are expected to be on the filter surface and transiting through the pores, yet efficiency was reproducible for many different blood samples, suggesting that WBCs and RBCs do not affect CTC capture when the ...
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Profiling of circulating tumor DNA in plasma of non‐small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in future application in mimicking circulating tumor cells
... tumoral cells (di- ameter greater than 15 µM) into ...200 cells (Figure ...five cells without spiking into total ...50 cells with the ...
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Tumor‐proximal liquid biopsy to improve diagnostic and prognostic performances of circulating tumor cells
... of tumor cells from the primary tumor and/or metastases is deleterious for the patient, it also becomes an opportunity to obtain relevant information for precision medicine using a noninvasive ...
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Hemodynamic forces tune the arrest, adhesion and extravasation of circulating tumor cells
... metastatic tumor cells (Figure 7A). We analyzed a high number of tumor cells, from several cell lines, that successfully mastered all step of brain metastatic cascade in brain ...
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EMT-Associated Heterogeneity in Circulating Tumor Cells : Sticky Friends on the Road to Metastasis
... including tumor cell migration or CTC survival [ 68 ...Cancer-Stem Cells (CSCs) [ 94 , 95 ], it is important to note that EMT induces the expression of stem cell attributes [ 96 , 97 ] and that certain EMT ...
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Clinical Validation of an Ultra High-Throughput Spiral Microfluidics for the Detection and Enrichment of Viable Circulating Tumor Cells
... Stained cells were concentrated and imaged with an Olympus inverted microscope (Tokyo, Japan) (Emission filters ET460/50m, ET535/50m and ET 605/70; Olympus, Tokyo, Japan) equipped with an automated ...Enriched ...
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Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes
... Circulating tumor cells (CTCs) are important clinical indicators for prognosis and treatment efficacy. However, CTC investigation is hampered by their low number, making the establishment of ...
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The challenges of detecting circulating tumour cells in sarcoma
... Circulating tumor cells can be detected in the peripheral blood and in theory have the potential to extravasate to form tumor metastases ( 17 ...are cells that circulate in the ...
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