• Aucun résultat trouvé

Reply to comment on "Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care"

N/A
N/A
Protected

Academic year: 2021

Partager "Reply to comment on "Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care""

Copied!
1
0
0

Texte intégral

(1)

ness than dynamic parameters. Faehnrich et al. [2] have recently demonstrated effec-tively in an animal study that the respirato-ry change in mitral flow under positive pressure ventilation becomes nonexistent when cardiac tamponade is present. In this particular case the hypotended patient could be considered a nonresponder to a fluid challenge by stroke volume variation indices, when giving him more fluids should be useful to increase cardiac output and/or mean arterial pressure.

Second, Starling’s law has shown that preinfusion cardiac preload, ventricular contractility, and afterload all influence the stroke volume response to volume load. Nevertheless, in the particular case of a patient with a left ventricular systolic dys-function, clinicians should keep in mind that positive pressure ventilation acts as a circulatory pump [3] that relatively im-proves contractility and decreases after-load.

Third, although we agree that the ques-tion “does our fluid challenge effectively increase patient cardiac preload?” is essen-tial to explain and validate the physiologi-cal background of a cardiac preload index [4], the answer to this question has no consequence for clinical practice if the index has been validated to be an accurate parameter for predicting the response of cardiac output and/or mean arterial pres-sure after volume infusion in all patho-logical situations. Practically, clinicians want to determine not the variation in the end-diastolic volume but rather whether the mean arterial pressure will increase (related to increase in cardiac output) after volume infusion.

Finally, cardiac responsiveness to vol-ume loading depends on different Starling curves (each reflecting a different inotropic state of the ventricles) and on the ventricu-lar interdependence [5]. Therefore the opti-mal index to predict the fluid responsive-ness, in all pathological situations, must assess these two estimations. As stated in our review [1], there are presently only few works clearly relevant to the specific fluid responsiveness, and the most useful param-eters for predicting cardiac output response to fluid challenge in mechanically ventilat-ed patients are the dynamics parameters. However, because the limits of these indi-ces have not yet been demonstrated in

par-ticular cases, and the echocardiography should be revitalized by three-dimensional technique, it seem to us that the challenge continues.

References

1. Bendjelid K, Romand JA (2003) Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care. Intensive Care Med 29:352–360

2. Faehnrich JA, Noone RB Jr, White WD, Leone BJ, Hilton AK, Sreeram GM, Mark JB (2003) Effects of positive-pres-sure ventilation, pericardial effusion, and cardiac tamponade on respiratory variation in transmitral flow velocities. J Cardiothorac Vasc Anesth 17:45–50 3. Beattie C, Guerci AD, Hall T, Borkon AM, Baumgartner W, Stuart RS, Peters J, Halperin H, Robotham JL (1991) Mechanisms of blood flow during pneu-matic vest cardiopulmonary resuscita-tion. J Appl Physiol 70:454–465 4. Tavernier B, Makhotine O, Lebuffe G,

Dupont J, Scherpereel P (1998) Systolic pressure variation as a guide to fluid therapy in patients with sepsis-induced hypotension. Anesthesiology

89:1313–1321

5. Jardin F (2003) Ventricular interdepen-dence: how does it impact on hemody-namic evaluation in clinical practice? Intensive Care Med 29:361–363

This reply refers to the comment available at http://dx.doi.org/10.1007/s00134-003-1846-4

K. Bendjelid (

) · J.-A. Romand Surgical Intensive Care Division, Geneva University Hospital, 1211 Geneva 14, Switzerland e-mail: Karim.Bendjelid@hcuge.ch Tel.: +41-22-3827452

Fax: +41-223827455 Intensive Care Med (2003) 29:1397

DOI 10.1007/s00134-003-1777-0

C O R R E S P O N D E N C E

Karim Bendjelid

Jacques-A. Romand

Reply to comment

on “Fluid responsiveness

in mechanically ventilated

patients: a review of indices

used in intensive care”

Received: 26 March 2003 Accepted: 30 March 2003 Published online: 22 May 2003 © Springer-Verlag 2003

Sir: We read with interest the comments by Michard and Reuter regarding our review article entitled “Fluid responsiveness in mechanically ventilated patients: a review of indices used in intensive care” [1] and would like to make the following remarks about their comments.

First, we have never stated that cardiac preload and fluid responsiveness (cardiac responsiveness to volume loading) are synonyms. Moreover, we disagree with these authors that improvement in techno-logical measurements of selected static cardiac preload indices should not increase the predictive value of fluid responsive-ness. As they highlight in their letter, we propose three-dimensional echocardiogra-phy to meet this challenge. We chose this technique as it allows the measurement of both ventricular volumes and contractility and the estimation of pericardial restraint. Therefore for physiological reasons we can accurately predict fluid responsiveness simply by assessing baseline cardiac pre-load when the technique used allows the discrimination of normal from failing ven-tricle (systolic and/or diastolic failure). Moreover, it seems to us that in particular cases such as cardiac tamponade (mechan-ic diastol(mechan-ic dysfunction) echocardiography could be a better index of fluid

Références

Documents relatifs

the deformed particles was slightly different from the width W of the channel as a consequence of the deformation of the lateral channel walls (bottom of Figure 3 a).. Each data

Apres avoir note Ie caractere parfois contradietoire des resultats obtenus dans plusieurs etudes, ces auteurs font porter leur argumentation sur deux idees

In this study we revisited the relative importance of (i) the relatively warm and salty waters entering the South Atlantic from the Indian Ocean mainly via the Agulhas Current

From the literature review it can be stated that owing to its relatively high chromium content and alloying elements, AISI 316L is oxidation resistant

Often, a design space exploration is performed within a “design under uncertainty” process which is a process of dimensioning the product in progressively and consciously

We use the Dunkirk case study to explain the role of geographical systems analysis, identifying loops that reinforce or regulate the sustainability of industrial symbiosis

To assess the radical depolymerization reaction of the native alginate ASBB, reducing sugars in the fractions obtained after 1, 3, 6, and 10 h of hydrolysis were quantified

(37) shows that both an intransitive and a transitive verb with a first-person object use a ma- prefix for their third- person masculine subject, whereas ty- would be expected if