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Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

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Academic year: 2021

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Figure 1 | Cripto is specifically expressed in EPI cells. (a) FISH and (b) immunofluorescence analyses of Cripto expression at E3.5
Figure 2 | Cripto sustains mESC self-renewal by modulating canonical Wnt signalling. (a) Immunofluorescence of Cripto on non-permeabilized WT and Cripto KO ESCs
Figure 3 | Cripto genetic ablation prevents ESC - EpiSC transition. (a) Representative photomicrographs of FGF/Activin (F/A) WT and Cripto KO cell colonies (scale bar, 100 mm)
Figure 5 | Cripto depletion attenuates ESC differentiation potential towards embryonic lineages in vitro
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