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Author Correction: Characterisation and localisation of the endocannabinoid system components in the adult human testis

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HAL Id: hal-02464404

https://hal.ehesp.fr/hal-02464404

Submitted on 4 Dec 2020

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Author Correction: Characterisation and localisation of the endocannabinoid system components in the adult

human testis

John Nielsen, Antoine D. Rolland, Ewa Rajpert-De Meyts, Christian Janfelt, Anne Jørgensen, Sofia Winge, David Kristensen, Anders Juul, Frédéric

Chalmel, Bernard Jégou, et al.

To cite this version:

John Nielsen, Antoine D. Rolland, Ewa Rajpert-De Meyts, Christian Janfelt, Anne Jørgensen, et al.. Author Correction: Characterisation and localisation of the endocannabinoid system compo- nents in the adult human testis. Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.1267.

�10.1038/s41598-020-58153-w�. �hal-02464404�

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1

Scientific RepoRtS | (2020) 10:1267 | https://doi.org/10.1038/s41598-020-58153-w

www.nature.com/scientificreports

Author correction:

characterisation and localisation of the endocannabinoid system components in the adult human testis

John e. nielsen, Antoine D. Rolland, ewa Rajpert-De Meyts , christian Janfelt, Anne Jørgensen  , Sofia B. Winge, David M. Kristensen, Anders Juul, frédéric chalmel, Bernard Jégou & niels e. Skakkebaek

Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-49177-y, published online 19 September 2019

This Article contains errors. Reference 51 was inadvertently omitted and is given below as Reference 1.

1. Sun, X. et al. Genetic loss of Faah compromises male fertility in mice. Biol Reprod. 80, 235–242 (2009).

As a result, in the Introduction,

“Studies in rodents demonstrated the presence of CNR1 protein in germ cells, Leydig cells and possibly also Sertoli cells11,12,13,14,15.”

should read:

“Studies in rodents demonstrated the presence of CNR1 protein in germ cells, Leydig cells and possibly also Sertoli cells11,12,13,14,15, CNR2 in germ cells and Sertoli cells, and FAAH mainly in spermatocytes and spermatids1

“Ablation of Cnr1 in mice had systemic and local effects on reproductive function; including decreased serum LH and testosterone levels16, but also disturbance of chromatin remodelling in spermatids13,14.”

should read:

“Ablation of Cnr1 in mice had systemic and local effects on reproductive function; including decreased serum LH and testosterone levels16, but also disturbance of chromatin remodelling in spermatids13,14. Genetic ablation of Faah led to elevated levels of AEA and caused impairment of fertility, which was rescued in mice with simultane- ous knock-out of Cnr11.”

Additionally, within the Results,

“The peritubular cell reaction was though weaker than in epithelial and myoid cells of blood vessels, which are known to express CNR1 (Fig. 2).”

should read:

“The peritubular cell reaction was though weaker than in epithelial and myoid cells of blood vessels (Fig. 2).”

Furthermore, within the Discussion, Published: xx xx xxxx

open

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2

Scientific RepoRtS | (2020) 10:1267 | https://doi.org/10.1038/s41598-020-58153-w

www.nature.com/scientificreports www.nature.com/scientificreports/

“CNR1 and CNR2, or CNR1 alone were described in murine Leydig cells and murine and frog germ cells, leading to a proposal that activation of CNR1 in Leydig cells is likely involved in steroidogenesis, while CNR2 in sper- matogonia B might promote meiotic entry in mice15,33,34.”

should read:

“CNR1 and CNR2, or CNR1 alone were described in murine Leydig cells and murine and frog germ cells, leading to a proposal that activation of CNR1 in Leydig cells is likely involved in steroidogenesis, while CNR2 in sper- matogonia B might promote meiotic entry in mice15,33,34,1.”

Finally, in Figure 2, the bottom right histology image is incorrectly labelled because of an inadvertent rotation of the image. The correct Figure 2 appears below as Figure 1.

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Cre- ative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not per- mitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

© The Author(s) 2020 Figure 1.

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