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Bioconjugated oligonucleotides: recent developments and thera-peutic applications

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Academic year: 2021

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Figure

Figure  1:  Mechanisms  of  antisense  oligonucleotides  (adapted  from Chan J. H. P. et al
Figure 3: Strategies for the delivery of ASO and/or siRNA. Adapted  from Järver et al
Figure 5: Cellular internalisation of GalNAc oligonucleotide conju- conju-gates, adapted from Alnylam
Figure 6: CPP grafting strategy on siRNA. A: Noncleavable  oligonucleotide  CPP  conjugate
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