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Sulcal Neuroanatomy and Relative Relationships using Spatial Gradients

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HAL Id: hal-02957840

https://hal.archives-ouvertes.fr/hal-02957840

Submitted on 5 Oct 2020

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Sulcal Neuroanatomy and Relative Relationships using

Spatial Gradients

Antonia Machlouzarides-Shalit, Guillermo Gallardo, Demian Wassermann

To cite this version:

Antonia Machlouzarides-Shalit, Guillermo Gallardo, Demian Wassermann. Sulcal Neuroanatomy and Relative Relationships using Spatial Gradients. Organization of Human Brain Mapping, Jun 2018, Singapore, Singapore. �hal-02957840�

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Cortical Mapping

Discussion & Conclusions

References

Objective: To characterise sulcal traits and relationships by means of spatial gradients. Our use of spatial

gradients allows for the investigation of sulcal associations on structural MRI images. We localise, identify

and relate sulci to examine inter-sulcal relationships, providing additional insight into cortical mapping.

1 Parietal Team, CEA, Inria Université Paris-Saclay, France

2 Athena Team, Inria Sophia Antipolis, Université Côte d'Azur, France

Antonia Machlouzarides-Shalit

1,2

Guillermo Gallardo

2

Demian Wassermann

1,2

Sulcal Neuroanatomy and Relative Relationships

using Spatial Gradients

Contact - antonia.machlouzarides-shalit@inria.fr

http://team.inria.fr/parietal/

OHBM 2018, 17 - 21 June, Singapore

PARIETAL - INRIA - FRANCE

5

Primary sulcal relations were consistent across

hemispheres and subjects, mirrored by

consistencies across many secondary sulci.

Our results reinforce our hypothesis of

localising sulci according to their spatial

gradients as a proof-of-concept study.

[1] Destrieux, C., Fischl, B., Dale, A. and Halgren, E. (2010). ‘Automatic parcellation of human cortical gyri and sulci using standard anatomical

nomenclature.’ NeuroImage, 53(1), pp.1-15.

Current atlases may struggle to account

for inter-individual variability of sulcal

characteristics.

Acknowledgements

:

This work acknowledges the support of ANR NeuroRef and

ERC-StG NeuroLang

How do we address this?

2

Cortical mapping based on assumption

of a few consistent sulci.

Localisation of each sulcus based on

relative positions to landmark sulci.

3

Methods

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Anteriority/Inferiority

of precentral sulcus

relative to central sulcus

Posteriority/Superiority

of precentral sulcus

relative to central sulcus

4

Results

Figure 2: Sulcal dependency paths,

where each sulcus of the frontal lobe

is organised in relation to previously

identified sulci, beginning with the

primary sulci, in this case the lateral

fissure and the central sulcus.

Relativity

Posterior of

Anterior of

Inferior of

Superior of

Lateral of

Medial of

E.g.

B is posterior of A

Position on cortex:

Black letters: Lateral surface

Blue letters

: Medial surface

Green letters

: Ventral surface

A

B

Figure 1: Probability density function depicting the relative coordinate

differences of the vertices of the precentral sulcus relative to the central

sulcus. The antero-posterior axis (in blue) refers to the difference on the

y-axis plane, and the supero-inferior axis (in yellow) on the z-axis plane.

We took the significant sulcal relations and

constructed dependency paths per lobe (see

Fig. 2), whereby any sulcus can be found based

on previously found sulci.

We applied the relative

position terms to 589

subjects (53% female,

age 29.3±3.28).

[1]

We

have

shown

how

primary

and

secondary sulci relate to each other and

have quantified our findings as being

consistent in a large population, thus

providing additional insight into cortical

mapping.

Antero-posterior axis

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