Sciences and Health research

The French landscape in Life

Sciences and Health research

Manpower resources of French life and health sciences research

(from : Futuris – Etude Biomed)

4346 4170

University staff members

Inserm researchers Other research agencies

Researchers and University staff members (full-time research equivalents) : 10677

Researchers from universities, Inserm, CNRS, CEA, Inra, Pasteur Institute involved in life and health sciences research

• 83 universities in France

• 50% of Inserm’s or Cnrs’s support concentrated on 5 universities

Marseille

• 80% of Inserm’s or Cnrs’s support

concentrated on 11 universities

Lyon

Grenoble

Montpellier Toulouse

Bordeaux

Strasbourg

• Government « campus » initiative

Nantes

Lille

Nancy

Paris 5, 6, 7, 11

New partnerships with

hospitals and universities

Assessment of the Strategy by the National Evaluation Agency of Research and Higher Education

Visiting committee:

Président :

Elias A. ZERHOUNI, Director, National Institutes of Health, USA Membres du comité :

Patrick AEBISCHER, President, Ecole polytechnique fédérale de Lausanne Peter AGRE, Directeur, Johns Hopkins Malaria Research Institute, Nobel Price Alain BEAUDET, President, Canadian Institutes of Health Research (CIHR)

Sir Leszek BORYSIEWICZ, Director general, Medical Research Council UK (MRC) ; Pierre CHAMBON, professeur honoraire, Collège de France ;

Jean-Paul CLOZEL, CEO d’Actelion Ltd ;

Lionel COLLET, President, University Claude-Bernard – Lyon 1 ; Jacques GLOWINSKI, professeur honoraire, Collège de France ; Bernard LEJEUNE, Secretary general, Académie de Grenoble ;

Claude LENFANT, Former director, National Heart, Lung and Blood Institute, NIH ; Michel van der REST, Director general, Synchrotron Soleil

Rose-Marie VAN LERBERGHE, CEO, Korian

Harold VARMUS, Director general, Memorial Sloan-Kettering Cancer Center, New York, Nobel Price

# 1 : France needs to boldly streamline and unify the

management system in Life Sciences and Health research

# 2 : Create a single National Institute for Life and Health Sciences Research

# 3 : Reevaluate the status, compensation, and career pathways of the French Life Sciences and Health scientists

# 4 : Period of transition needed for implementation

Assessment of the strategy by AERES

4 Core recommendations

Aviesan

Alliance nationale pour les Sciences de la Vie et de la Santé

National Alliance for Life Sciences and Health

Created on April 8, 2009

9 Members: Rationalisation of the Life Sciences and Health research:

Inserm as the unique coordinator of all French research programmes in the sector (mission statement entrusted by the Ministry of Higher

Education and Research and the Ministry of Health to the new Director- General of Inserm – November 2007)

ALLISTENE

National Alliance of Digital Sciences and Technologies

(17/12/2009)

Members: CDEFI, CEA, CNBRS, CPU, INRIA, Institut Telecom

ANCRE

National Alliance for Energy Research Coordination

(17/07/2009)

Founding members: CNRS, CEA, IFP Associated members: CPU, ANDRA, BRGM, CSTB, IFREMER, INERIS, INRA, IRSN, INRETS, ONERA

ALLEnvi

National Alliance for Environment (09/02/2010)

Members: BRGM, CEA, Cemagref Cirad, CNRS, CPU,INRA IRD, Ifremer, LCPC,

Météo France, MNHN

ATHENA

National Alliance of Humanities, Human Sciences and Social Sciences

(22 Juin 2010)

Members: CNRS, CGE, CPU, Ined

Where are we now?

• Health, Welfare, Food & Biotechnologies

• Information & Communication, Nanotechnologies

• Environment & Eco-technologies And, as transversal aspects:

• To reinforce the public-private interface

• To put Europe « at the heart » of the process

The French National Strategy for Research & Innovation

3 priorities

 To coordinate strategic analysis, scientific

programming and the operational implementation of research in Life Sciences and Health

 To give a boost to translational research

 To encourage trans-disciplinarity

 To promote the dissemination of Knowledge and the use of discoveries

 To define common positions at the European and International levels

 To reinforce the partnerships between research institutions and universities

 To simplify the administrative procedures for the daily-life of laboratories and researchers

Aviesan objectives

http://www.aviesan.fr/en

Scientific coordination

Operational coordination

Ten Thematic Institutes

covering the entire field of Life Sciences and Health research

Neurosciences Cognitive Sciences

Neurology, Psychiatry

Genetics, Genomics Bioinformatics

Immunology Hematology Respiratory

diseases

Microbiology Infectious

diseases

Public Health

Health Technologies Cancer

Cell Biology Development

Molecular and Structural

Biology

Circulation Metabolism

Nutrition

The French Alliance for Life and Health Sciences: Aviesan

 To set up “the 2010 programming in Life and Health Sciences” at the national level (protocol agreement with the National Funding Agency, 2009)

 Our Strategy for Health and Life Sciences (2010-2015)

 To develop coordinated partnerships with

Universities and Hospitals for the support of top-level research centres (Centres of Excellence)

 Swine flu: to launch coordinated research axes

 To set up new partnerships with pharmaceutical industry

 To put forward Joint programming Health issues at the European level

First

achievements

and ongoing actions

To reinforce attractiveness and partnerships between public research and health industries

Industriels

COPIO

GAP

Maturation de projets ambitieux, preuve de

Faciliter et accompagner l’accès aux compétences et capacités de la

recherche académique

COVALLIANCE

Simplifier les partenariats ITMO

Health Technologies

Industry

To incubate ambitious

projects, Proof of concept

Simplify the partnerships

To facilitate access to

competencies and capacities of academic research

• To launch top-level initiatives for a limited number of research fields of excellence

• To offer attractive positions to international scientific leaders

35 billion €

21.9 devoted to Research and Higher Education

" Investments for the future " : a

major opportunity for boosting R&I in

France

• Equipment of Excellence : 1bn €

=> Research equipment from 1 to 20M€

• 400M€ for the acquisition

• 600M€ endowment for operational costs

• 52 projects funded (340M€); 15 in « Biology and Health »

• Large cohorts : 200M€ fund (endowment)

=> 10 cohorts funded (70 M€ for 10 y)

• National Research Infrastructures: 450M€

=> 10 projects funded, involving Inserm and CNRS + one project of Pre-industrial Demonstrator in

Biotechnology, also lead by Inserm : PGT (Vector for Gene therapy) – 20 M€

First results of the

Investments for the future (1)

• BIOBANQUES (public health, biomarkers), coordination Inserm

• F- CRIN (clinical research), coordination Inserm

• HIDDEN (biosafety level 4 laboratory), Inserm

• France-BioImaging (cell imaging), coordination CNRS

• FRISBI (structural biology), coordination CNRS

• PHENOMIN (phenotyping), coordination CNRS

• ProFI (proteomics), coordination CNRS

• France Génomique (genomics), coordination CEA

• EMBRC-France (marine biology), université Pierre et Marie Curie, CNRS

9 national research infrastructures for biology and health

220 millions € for 10 years

• 6 University Hospital Institutes

• 100 Laboratories of Excellence

consumable) – 24 in “Health and Biology”

• Initiatives of Excellence

• 6 Research & Technology Institutes

25% consumable) – 1 in “Health and Biology” (infectiology)

• Calls for competitive clusters :

• Collaborative R&D projects (300M€) 2 ongoing

First results of the

Investments for the future (2)

• Neurosciences (Paris)

• Cardiometabolism and nutrition (Paris)

• Genetic diseases (Paris)

• Cardiology (Bordeaux)

• Surgery (Strasbourg)

• Infectious diseases (Marseille)

6 University Hospitals

« Instituts hospitalo-universitaires »

350 millions € for 10 years

Investments for the Future - calls for proposals in Technology Transfer

Streamline process with a new organisation involving

 SATT : Societies for Accelerating Technology Transfert

• Regional Technology Transfer Office shared and led by several Universities

• Aimed at pooling and developing : Technology Transfer; Proof of concept ; Maturation ; Intellectual Property

• Multidisciplinary based

• Involved French public research bodies (Inserm, CNRS, CEA, etc.) as board members

 CVT : National Technology Transfer Office dedicated to

French public research bodies (Aviesan in Life

Technology Transfer in Life Sciences and Health

SATT : call for proposals

• 14 projects submitted

• 5 selected & financed for the 1st round (budget )

• 4 under preparation

Conectus Alsace 7900 researchers 42% in Life Science Lutech IDF

10000 researchers 33% in Life Science

Ile-de-France Innov’

18000 researchers 39% in Life Science

Midi-Pyrénées 5000 researchers 29% in Life Science

PACA Corse 6000 researchers 30 % in Life Science

www.aviesan.fr

END