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Daphnanes diterpenes from the latex of Hura crepitans L. and activity against human colorectal cancer cells Caco-2

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Academic year: 2021

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Figure 1. (A) Cytotoxicity of the crude extract of  H. crepitans latex. IEC6 (normal intestinal  cell  line),  Caco-2  and  HT29  (colon  cancer  cell  lines)  cells  were  incubated  with  different  concentrations of the crude extract of the latex of H
Figure  2.  (A)  Cytotoxicity  of  daphnanes  and  cerebrosides  of  the  H.  crepitans  latex
Figure 3. Structure of  mono-esterified daphnanes isolated from the latex of  Hura crepitans
Table  I.  1 H-  and  13 C-NMR  (CDCl 3 )  data  (δ  in  ppm)  for  the  daphnane-type  orthoesters  huratoxin  (1),  2’,3’-dihydrohuratoxin  (4)  and  6’- 6’-oxohuratoxin (5) and daphnane-type esters prohuratoxin (2), and stelleralide J (3)
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