Voltage-independent GluN2A-type NMDA receptor Ca2+ signaling promotes audiogenic seizures, attentional and cognitive deficits in mice
Texte intégral
Figure
Documents relatifs
We investigated the effect of psychotomimetic NMDA receptor antagonists ketamine and PCP and demonstrated that in the visual cortex NMDA receptor hypofunction causes phase- coupling
Inhibition of PKC before the administration of this priming dose of morphine prevented serine phosphorylation of the MOR, and, consequently, the receptor maintained its control over
L-NAME (10 mg/kg) attenuated ketamine (15 mg/kg)-induced spatial working memory and retention deficits in the radial water maze paradigm. L-NAME, applied at 3 mg/kg however,
CRNL Author Major role in the acquisition of data, drafting and revising the manuscript for intellectual content, analysis and interpretation of the data, and clinical evaluation
Overall, the burst of microstructural anomalies detected in the cerebral cortex, the hippocampus, and the thalamus of Grin2a −/− mice aged 1 month had sponta- neously and
Using the Russian sturgeon as the donor fin-cell species and the sterlet as the recipient egg species we could establish the basic steps of the nuclear transfer technique..
The first portion of the results presents the findings of the random forest model, maps the living conditions indicator (probability that an area is a slum), examines important
A fundamental difference between NMDAR subtypes is their channel maximal open probability (Po), which spans a 50-fold range from ~0.5 for NR2A-containing receptors to ~0.01 for