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Examining how PSMB11 orchestrates T cell development

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Academic year: 2021

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Figure 1. MHC class I presentation pathway. Intracellular proteins are degraded into 8- 8-10 amino-acid-long peptides by the proteasome and translocated to the endoplasmic reticulum (ER) via the transporter associated with antigen prese
Figure 4. Thymus morphology in the mouse. Hematoxylin and eosin staining of a normal thymus from a 3-month-old B6C3F1 mouse showing the cortex in dark blue and the medulla in light blue
Figure 5. PSMB11 is a master regulator of the transcriptome in cTEC. (A) Differential gene expression from cTECs between WT and Psmb11 -/- mice at 10 weeks of age (mean of 3 replicates per genotype)
Figure 6. Impact of Psmb11-deletion on CD4 and CD8 thymocyte numbers. (A) Flow cytometry analysis of thymocytes from WT and Psmb11 -/- mice
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