E
UPOCUSE OF GLYCOSURFACTA
OF POLYHIPES
C
ÉDRICB
OYÈRE1,
A
UDREYF
P
AQUOT3 1Center for Education and Research on Macromolecules, University of Liège. Chemistry
Sart
2
Laboratory of Chemical Engineering, University of Liège,
3Laboratory of Industrial Biological Chemistry, University of Liège. Gembloux Agro
(GxABT), 5030 Gembloux, Belgium
‘‘Superzym’’ project is supported by the French Community of Belgium under the scientific
‘‘Concerted Research Actions
Porous polymer structures can be prepared by high internal phase emulsion (HIPE) polymerization. In
these emulsions, the internal droplets phase exceeds 70% of the total volume and the monomer is
located in the continuous phase. After polymerization, the removal of the droplet phase creates cavities
in the polymer matrix. The resulting materials, called polyHIPEs,
and sustains a variety of applications such as scaffolds for tissue engineering
immobilization of proteins
4etc.
dioxide (scCO
2) as an alternative to the traditional organic solvents
case, low molecular weight ionic perfluoropolyether (PFPE) surfactant was used
water/CO
2emulsion. In addition to be an
friendlier medium, scCO
2is easy to remove from the template
depressurization.
In this work, we explore the use of novel non
for the synthesis of polyHIPEs.
6whereas the fluorinated tail has a strong affinity for the scCO
polyHIPEs were characterized by scanning e
impact of the surfactant on the porous polymer properties will be discussed. The synthesis of the
surfactants will also be presented. A first approach consists in the enzymatic esterification of sugars
fluorinated acid derivatives.
6Another strategy combines
the versatility of the thiol-Michael addition reaction
_____________________________
1. S. D. Kimmins and N. R. Cameron,
2. Y. Lumelsky, J. Zoldan, S. Levenberg and M. S. Silverstein, 3. I. Pulko, J. Wall, P. Krajnc and N. R. Cameron,
4. F. Fernández-Trillo, J. C. M. van Hest, J. C. Thies, T. Michon, R. Weberskirch and N. R. Cameron, Adv. Mater., 2009, 21, 55-59.
5. R. Butler, C. M. Davies and A. I. Cooper, 6. A. Favrelle, C. Boyère, P. Laurent, G. Broze,
Carbohydr. Res., 2011, 346
7. C. Boyère, A. Favrelle, G. Broze, P. Laurent, K. Nott, M. Paquot, C. Blecker, C. Jérôme and A. Debuigne, Carbohydr. Res.
UPOC
2012
–
POROUS POLYMER-BASED SYSTEMS: FROM D GARGNANOUSE OF GLYCOSURFACTANTS FOR THE SYNTHESIS
OF POLYHIPES IN SUPERCRITICAL CARBON DIOXIDE
F
AVRELLE1,
A
LEXANDREL
ÉONARD2,
J
EAN-P
AULP
3,
C
HRISTINEJ
ÉRÔME1*,
A
NTOINED
EBUIGNE1*cedric.boyere@ulg.ac.be
Center for Education and Research on Macromolecules, University of Liège. Chemistry
Sart-Tilman (B6a) 4000 Liège, Belgium;
Laboratory of Chemical Engineering, University of Liège, Sart-Tilman (B6a) 4000 Liège, Belgium
Laboratory of Industrial Biological Chemistry, University of Liège. Gembloux Agro
(GxABT), 5030 Gembloux, Belgium.
‘‘Superzym’’ project is supported by the French Community of Belgium under the scientific
‘‘Concerted Research Actions- ARC’’ program.
Porous polymer structures can be prepared by high internal phase emulsion (HIPE) polymerization. In
droplets phase exceeds 70% of the total volume and the monomer is
After polymerization, the removal of the droplet phase creates cavities
The resulting materials, called polyHIPEs,
1exhibit highly
a variety of applications such as scaffolds for tissue engineering
2, support for catalyst,
Interestingly, Cooper et al. reported the use of
alternative to the traditional organic solvents for the synthesis of HIPE.
weight ionic perfluoropolyether (PFPE) surfactant was used
In addition to be an inexpensive, non-toxic, non-flammable and environmentally
is easy to remove from the template since it reverts to gaseous phase upon
In this work, we explore the use of novel non-ionic fluorinated modified carbohydrates
6,7
The hydrophilic head of the surfactant consists in a sugar moiety
uorinated tail has a strong affinity for the scCO
2phase. The resulting
polyHIPEs were characterized by scanning electron microscopy, pycnometry and porosimetry. The
impact of the surfactant on the porous polymer properties will be discussed. The synthesis of the
surfactants will also be presented. A first approach consists in the enzymatic esterification of sugars
Another strategy combines the selectivity of the enzymatic catalysis and
Michael addition reaction.
7_____________________________
S. D. Kimmins and N. R. Cameron, Adv. Funct. Mater., 2011, 21, 211-225.
Y. Lumelsky, J. Zoldan, S. Levenberg and M. S. Silverstein, Macromolecules, 2008, I. Pulko, J. Wall, P. Krajnc and N. R. Cameron, Chem. Eur. J., 2010, 16, 2350-2354.
Trillo, J. C. M. van Hest, J. C. Thies, T. Michon, R. Weberskirch and N. R. Cameron, 59.
R. Butler, C. M. Davies and A. I. Cooper, Adv. Mater., 2001, 13, 1459-1463.
A. Favrelle, C. Boyère, P. Laurent, G. Broze, C. Blecker, M. Paquot, C. Jérôme and A. Debuigne,
346, 1161-1164.
C. Boyère, A. Favrelle, G. Broze, P. Laurent, K. Nott, M. Paquot, C. Blecker, C. Jérôme and A. Carbohydr. Res., 2011, 346, 2121-2125.
DESIGN TO APPLICATION ARGNANO (I),3-7JUNE ,2012
THE SYNTHESIS
BON DIOXIDE.
P
IRARD2,
M
ICHELCenter for Education and Research on Macromolecules, University of Liège. Chemistry Department,
4000 Liège, Belgium;
Laboratory of Industrial Biological Chemistry, University of Liège. Gembloux Agro-Bio Tech
‘‘Superzym’’ project is supported by the French Community of Belgium under the scientific
Porous polymer structures can be prepared by high internal phase emulsion (HIPE) polymerization. In
droplets phase exceeds 70% of the total volume and the monomer is
After polymerization, the removal of the droplet phase creates cavities
interconnected voids
, support for catalyst,
3reported the use of supercritical carbon
for the synthesis of HIPE.
5In this
weight ionic perfluoropolyether (PFPE) surfactant was used to stabilize the
mable and environmentally
reverts to gaseous phase upon
fluorinated modified carbohydrates as surfactants
The hydrophilic head of the surfactant consists in a sugar moiety
The resulting acrylamide
and porosimetry. The
impact of the surfactant on the porous polymer properties will be discussed. The synthesis of the
surfactants will also be presented. A first approach consists in the enzymatic esterification of sugars by
enzymatic catalysis and
, 2008, 41, 1469-1474. 2354.
Trillo, J. C. M. van Hest, J. C. Thies, T. Michon, R. Weberskirch and N. R. Cameron,
C. Blecker, M. Paquot, C. Jérôme and A. Debuigne, C. Boyère, A. Favrelle, G. Broze, P. Laurent, K. Nott, M. Paquot, C. Blecker, C. Jérôme and A.
