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Analysis of temporal gait features extracted from accelerometer-based signals during ambulatory walking in Parkinson’s disease

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pdfcrowd.com Date: Tuesday, June 21, 2016

Session Title: Technology

Session Time: 12:30pm-2:00pm

Location: Exhibit Hall located in Hall B, Level 2

Analysis of temporal gait features extracted from

accelerometer-based signals during ambulatory

walking in Parkinson’s disease

M. Boutaayamou, M. Demonceau, O. Brüls, J.G. Verly, G. Garraux (Liège, Belgium) Meeting: 20th International Congress

Abstract Number: 574

Keywords: Gait disorders: Clinical features, Parkinsonism

Session Information

Objective: To perform a proof-of-concept study showing the utility of versatile algorithms aimed at

objectively quantifying the duration of refined gait features during ambulatory walking in a patient with Parkinson’s disease (PD) in OFF/ON medication states as compared with an age-matched control subject.

Background: Gait features in PD are characterized by spatial and temporal pattern disturbances. In clinical

practice, these are usually assessed visually on a short walking trial using subjective scales such the Unified Parkinson’s disease Rating Scale (UPDRS). This has obvious limitations including subjectivity and inter-rater variability. To address this issue, we recently developed and validated an accelerometer-based system to quantify gait features during ambulatory walking [1].

Methods: We recorded acceleration signals in a healthy control (male; age=67 years; height=1.72 m;

weight=90 kg), with no history of gait abnormalities, and in a PD patient (female; age=69 years; height=1.68 m; weight=58 kg; disease duration=22 years) in OFF (18 hours off medication) and ON (under usual

medications) states. Gait signals were obtained as subjects walked back and forth on a 15 m long straight walkway for 1 to 2 min, at their usual speed using an ambulatory system that included four synchronized accelerometers attached directly to the subject’s regular shoes at the level of the (right/left) heels and toes. We developed versatile algorithms [1] to extract durations of (1) stance and stance sub-phases (i.e., loading response, mid-stance, and push-off), (2) swing, and (3) double support. Here we report data on swing and double support times.

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Conclusions: Our data show that our algorithms provide relevant gait parameters that can discriminate

between a PD patient in OFF/ON states and a healthy control. To the best of our knowledge, this is also one of the first demonstrations that refined temporal gait features to be quantified outside a

laboratory/hospital setting. The proposed algorithms are now being used to analyze the gait of a larger set of subjects including controls and PD patients to confirm the relevance of these refined gait parameters. References: [1] Boutaayamou, M., et al. Development and validation of an accelerometer-based method for quantifying gait events. Medical Engineering and Physics, 37, 226–232, 2015.

To cite this abstract in AMA style:

M. Boutaayamou, M. Demonceau, O. Brüls, J.G. Verly, G. Garraux. Analysis of temporal gait features extracted from accelerometer-based signals during ambulatory walking in Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2).

http://www.mdsabstracts.org/abstract/analysis-of- temporal-gait-features-extracted-from-accelerometer-based-signals-during-ambulatory-walking-in-parkinsons-disease/. Accessed August 17, 2017.

MDS Abstracts -

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