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Policy briefs and best practice guidelines

Policy briefs and best practice guidelines

POLICY BRIEFS The livestock farming industry could benefit from the vast possibilities that digitalization and the Internet have to offer, but this requires better interoperability (mean- ing how different products or systems talk to each oth- er) and connectivity of different intelligent systems and technologies. PROHEALTH research suggests that stake- holders should be encouraged to promote the develop- ment and on-farm adoption of sensor technologies and data analytics which facilitate earlier response to dis- ease. When using novel technology and sophisticated digital monitoring tools, the occurrence of respiratory and enteric disease in nursery and grow-finish pigs can be anticipated a day, or even as early as a week, before clinical signs occur. This gives farmers and veterinarians crucial time to successfully contain the disease before it becomes a problem, as the following examples illustrate.
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EMQN best practice guidelines for the molecular genetic testing and reporting of chromosome 11p15 imprinting disorders: Silver–Russell and Beckwith–Wiedemann syndrome

EMQN best practice guidelines for the molecular genetic testing and reporting of chromosome 11p15 imprinting disorders: Silver–Russell and Beckwith–Wiedemann syndrome

Molecular genetic testing for the 11p15-associated imprinting disorders Silver –Russell and Beckwith–Wiedemann syndrome (SRS, BWS) is challenging because of the molecular heterogeneity and complexity of the affected imprinted regions. With the growing knowledge on the molecular basis of these disorders and the demand for molecular testing, it turned out that there is an urgent need for a standardized molecular diagnostic testing and reporting strategy. Based on the results from the first external pilot quality assessment schemes organized by the European Molecular Quality Network (EMQN) in 2014 and in context with activities of the European Network of Imprinting Disorders (EUCID.net) towards a consensus in diagnostics and management of SRS and BWS, best practice guidelines have now been developed. Members of institutions working in the field of SRS and BWS diagnostics were invited to comment, and in the light of their feedback amendments were made. The final document was ratified in the course of an EMQN best practice guideline meeting and is in accordance with the general SRS and BWS consensus guidelines, which are in preparation. These guidelines are based on the knowledge acquired from peer-reviewed and published data, as well as observations of the authors in their practice. However, these guidelines can only provide a snapshot of current knowledge at the time of manuscript submission and readers are advised to keep up with the literature.
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Centres of excellence in heart valve surgery: are there standards for best practice?

Centres of excellence in heart valve surgery: are there standards for best practice?

expertise in valvular heart disease imaging, need to inte- grate newer risk strati fication indices, require to be informed of recent changes in guidelines and cutting-edge therapeutic options in valvular heart disease. 2 3 All this implies that professionals involved in the ‘Heart Valve Centres of Excellence ’ (advanced valve clinics model) should have all the competencies to treat complex valvular heart disease or high-risk patients, and deep knowledge in the latest technologies and treatment methods (ie, valve repair, percutaneous valve intervention). These centres, thus, have all the facilities to treat and refer patients for valvular surgery/intervention. Often, they have a high- volume operation rate on valvular heart disease, which is believed to be associated with better repair results and potentially improved outcome. 10 This partly explains why there is no obligation to refer patients eligible for surgical repair in centres of excellence. 3 4
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Good practice guidelines for participatory multi-site videoconferencing

Good practice guidelines for participatory multi-site videoconferencing

We use the term “good practices” in recognition that “best practices” depend on the specific context of the multi-site videoconference and the technology used, the individual circumstances surrounding the task at hand, the content of the videoconference, and the group and organizational dynamic. Every group is different; likewise every multi-site videoconference is different and may require various levels of planning and execution. The charts and checklists proposed in this appendix are voluntary and flexible recommendations. Readers can adopt the recommendations they feel are most appropriate to their own multi-site videoconferencing situations at a rate they are comfortable with. We encourage readers to print their own copies of the appendix and to modify the guidelines according to their own needs. If further publications are made from material in this report or appendix, the report should be referenced. The suggested reference for this report: Molyneaux, H., O'Donnell, S., Liu, S., Hagerman, V., Gibson, K., Matthews, B. et al. (2007). Good Practice Guidelines for Participatory Multi-Site Videoconferencing. Fredericton: National Research Council. ERB-1151. NRC 49869.
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Practice guidelines on the use of erythropoiesis-stimulating agents in the treatment of chemotherapy-induced anemia

Practice guidelines on the use of erythropoiesis-stimulating agents in the treatment of chemotherapy-induced anemia

In lymphoid tumours, a study by Hedenus et al. in a mixed tumour setting of several lymphoid malignancies showed a worse outcome on OS but identical PFS. Large studies in diffuse large B-cell lymphoma (DLBCL) (LNH03-6B) and Hodgkin’s disease (GHSG-H15) and a smaller study in (acute) lymphoblastic lymphoma/Burkitt’s lymphoma (ALL- LL-BL) (Mattiuzzi) showed no significant differences in outcome. The conclusion seems to be that in lym- phoid tumours results should be considered as neutral. In breast cancer, conflicting results were recorded in different studies. A study published by Leyland- Jones et al. in 2005 (BEST) in metastatic breast cancer and the preliminary results of the PREPARE study in neo-adjuvant setting presented by Untch reported a worse outcome for ESA-treated patients, whereas other studies such as reported by Aapro et al. in 2008 (BRAVE), Chang et al. in 2005 (EPO-CAN-17) and Moebus et al. in 2007 did not find any outcome diffe- rence in terms of OS or PFS.
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POW WOW Virtual laboratories and best practice guides for the prediction of Waves Wakes and Offshore

POW WOW Virtual laboratories and best practice guides for the prediction of Waves Wakes and Offshore

The core of the short-term prediction work package is to support research by helping with development of the models by furnishing a Virtual Laboratory, where other modellers can try their models on the same footing with everyone else, using identical data. Additionally, we will enhance the outreach of the short-term forecasting community through the set-up of an Expert Group for short-term forecasting, trying to work closely together with the Commission and other European and world-wide stakeholders. Resources are earmarked for visits to interested parties to disseminate the state of the art in short- term forecasting inside and outside of Europe. This group also is to co-ordinate and disseminate results obtained in national projects, to try to avoid overlap of effort, but also to make sure that all researchers in the field are aware of the latest developments and research results. This includes evaluation of the input data for models, not only trying to disseminate the latest efforts within the meteorological community to the modellers, but also by sensitising the meteorological community to the higher accuracy demand of this particular customer of their data. At the other end of the data flow, the use of short-term predictions on the clients’ side can be improved upon by establishing some guidelines of best practice in their use. These practices will first be devised in close conjunction with current users of predictions, and then will be distributed to a larger audience through training courses and a separate workshop, and dissemination activities on conventional energy conferences and in power industry journals. This would have the side benefit that utilities with low exposure to wind power will be able to work constructively with wind, and not completely reject wind power on grid stability grounds.
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Perineal prevention and protection in obstetrics: CNGOF Clinical Practice Guidelines

Perineal prevention and protection in obstetrics: CNGOF Clinical Practice Guidelines

Should difficulties arise, repair of OASIS can be delayed for several hours to enable it to be performed in the best possible conditions (Grade C). 11. Does caesarean delivery prevent perineal injuries and dysfunctions? For a long time, vaginal delivery has been considered the principal cause of functional disorders of women's pelvic floor, whether these involve urinary or anal incontinence, pelvic organ prolapse, or sexual disorders. Caesarean delivery might thus appear to be an effective means of avoiding them. Nonetheless the association between mode of delivery and perineal dysfunction has not been clearly established, and the preventive effect of caesarean delivery is currently controversial. The validity of these reports remains questionable, for they have been retrospective and cohort studies, rather than randomised trials that compare both types of delivery. The studies are therefore likely to comport biases, that is, to involve the selection of a particular profile of women in the caesarean group, who might have individual characteristics that mean that they are at less risk of perineal injuries and dysfunctions.
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Best practice principles for management of children with developmental coordination disorder (DCD) : results of a scoping review

Best practice principles for management of children with developmental coordination disorder (DCD) : results of a scoping review

also decrease the negative impact DCD is reported to have on families (Novak et al. 2012). Our results highlight the many authors recommending find- ing innovative ways to manage all of the children who have DCD (Wehrmann et al. 2006; Forsyth et al. 2008; Missiuna et al. 2012b); this is echoed in emerging literature in childhood disabil- ity that proposes guidelines to determine the optimal type and intensity of services (Palisano & Murr 2009), response to interven- tion approaches (McIntosh et al. 2011), school-based consultative models (Hutton 2009) as well as interventions and new models of service delivery to improve service accessibility and quality (Camden et al. 2010, 2013; Kolehmainen et al. 2012). The princi- ples identified in this scoping review are not new in childhood disability, but the need for population-based interventions appears to be more critical in the DCD field. The high prevalence of DCD compared with other childhood disabilities, and the resultant stressors on health care resources, explain the greater emphasis on implementing graduated response care pathways which are perceived to be more cost-efficient (Wehrmann et al. 2006; Forsyth et al. 2008; Missiuna et al. 2012b).
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Best practice principles for management of children with developmental coordination disorder (DCD): results of a scoping review

Best practice principles for management of children with developmental coordination disorder (DCD): results of a scoping review

also decrease the negative impact DCD is reported to have on families (Novak et al. 2012). Our results highlight the many authors recommending find- ing innovative ways to manage all of the children who have DCD (Wehrmann et al. 2006; Forsyth et al. 2008; Missiuna et al. 2012b); this is echoed in emerging literature in childhood disabil- ity that proposes guidelines to determine the optimal type and intensity of services (Palisano & Murr 2009), response to interven- tion approaches (McIntosh et al. 2011), school-based consultative models (Hutton 2009) as well as interventions and new models of service delivery to improve service accessibility and quality (Camden et al. 2010, 2013; Kolehmainen et al. 2012). The princi- ples identified in this scoping review are not new in childhood disability, but the need for population-based interventions appears to be more critical in the DCD field. The high prevalence of DCD compared with other childhood disabilities, and the resultant stressors on health care resources, explain the greater emphasis on implementing graduated response care pathways which are perceived to be more cost-efficient (Wehrmann et al. 2006; Forsyth et al. 2008; Missiuna et al. 2012b).
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Best Practice Guidelines for Cooperative Compliance with Nuclear Non-Proliferation Obligations

Best Practice Guidelines for Cooperative Compliance with Nuclear Non-Proliferation Obligations

Neutron Sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187 Matthias Englert and Anne Harrington 10 The Proliferation Security Initiative: A Tentative Assessment . . . . . . 213 Gabriella Venturini

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A proposition of service architecture and best practice for business intelligence projects within an IT department of an international bank

A proposition of service architecture and best practice for business intelligence projects within an IT department of an international bank

Figure 3-2 Application Software Domains For me, my job according to the internship was to define the enterprise rules and guidelines in the domain of Business Intelligence. I was expected to conclude the definition of Business Intelligence. And then I should talk about the benefits brought to the enterprise by Business Intelligence systems. I can not forget the paragraph of attention points in the design and development of a Business Intelligence system. The ecosystem and governance elements are also included in my work. Owing to EAGLE, the language of General Software Service Reference Model and platform Instantiations in the language of EAGLE Patterns will be designed and defined with great care and ordinance with the IT Group. Last but not least I must provide rules and best practices, which is the main target of the job, for Business Intelligence projects in BNP Paribas IT Group.
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Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit

Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit

in collaboration with the GFRUP and the ADARPEF Groupement Francophone de Réanimation et Urgences Pédiatriques Association des Anesthésistes Réanimateurs Pédiatriques d’Expression Française. Coordinating expert: Jean‑François Timsit—Medical and infectious dis‑ eases ICU (MI2), APHP, Bichat hospital; IAME U1137—INSERM/University Paris Diderot, Paris F75018, France. Organizers: Laetitia Bodet‑Contentin—Medical Intensive Care Unit, INSERM CIC 1415, CRICS‑TriGGERSep network, CHRU de Tours and Université de Tours, France; Virginie Maxime—Surgical and Medical Intensive Care Unit, le Hôpital Raymond Poincaré 9230 Garches. Experts group for adult critically ill patients: Louis Bernard, Silvia Calvino‑Gunther, Michael Darmon, Jean Dellamonica, Marc Leone, Alain Lepape, Olivier Leroy, Jean‑ Christophe Lucet, Olivier Mimoz, Benoît Misset, Jean‑Jacques Parienti, Jean‑ Pierre Quenot, Antoine Roch, Matthieu Schmidt, Michel Slama, Bertrand Sou‑ weine, Jean‑Ralph Zahar, Walter Zingg. Experts group for paediatric critically ill patients: Writing Julien Baleine, Eric Desruennes, Zied Merchaoui. Scoring Botte Astrid, Demaret Pierre, Le Roux Bénédicte, Michel Fabrice, Milesi Christophe. Paediatric review by Anne Laffargue and Francis Veyckemans (scientific council of the ADARPEF). Working group: SRLF guidelines and evaluation committee: Max Guillot (Strasbourg), Naïke Bigé (Paris), Laetitia Bodet‑Contentin (Tours), Rémi Bruyère (Bourg‑en‑Bresse), Charles Cerf (Suresnes), Julien Duvivier (Draguignan), Henri Faure (Aulnay‑sous‑Bois), Marion Grimaud (Paris), Sandrine Jean (Paris), Antoine Kimmoun (Vandœuvre‑lès‑Nancy), Erwan L’Her (Brest), Éric Mariotte (Paris), Virginie Maxime (Garches), Chirine Mossadegh (Paris), Claire Pichereau (Poissy), Élie Zogheib (Amiens).
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Format Guidelines and Examples

Format Guidelines and Examples

Example (with multiple editors): Richie, Beth E. (2004) “Challenges Incarcerated Women Face as they Return to their Communities: Findings from Life Histories Interviews”, in M. Chesney-Lind & L. Pasko (eds.), Girls, Women and Crime: Selected Readings, Thousand Oakes: Sage Publications, pp. 231-245.

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The case of advocacy planning: the limits of pluralism as a basis for policy and planning practice.

The case of advocacy planning: the limits of pluralism as a basis for policy and planning practice.

The task, then, is to free politics from those constraints: to change and expand the role of political decisions and to bring the matters that are of major social [r]

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Applicability and generalisability of the results of systematic reviews to public health practice and policy: a systematic review.

Applicability and generalisability of the results of systematic reviews to public health practice and policy: a systematic review.

Assessing applicability and external validity is difficult [4]. As well, deciding which items are relevant and should be reported is difficult. Further, the importance of some items may vary by context (e.g., assessing phar- macologic treatments or nonpharmacologic treatments). Therefore, when planning a systematic review, the pro- tocol should define which applicability items are impor- tant and should be collected and reported. Not all of the applicability items we evaluated necessarily interact with effect size. However, methodological work evaluating the impact of applicability on effect size is lacking, and therefore, making a definitive statement on this issue is difficult. Further, even if some applicability items do not interact with effect size, details of applicability items must be provided to allow clinicians, patients and deci- sion makers decide whether and how they will apply the results in clinical practice. Items identified as possibly interacting with treatment effect estimates should be offered as a priori explanations of heterogeneity, and an exploration of whether treatment differs across these characteristics should be undertaken. Other items aimed at helping readers appraise the applicability of the trials in their context should be reported. Online addenda now provide a great opportunity to adequately describe the included studies for interested readers without bur- dening every reader.
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A comparison of budesonide/formoterol maintenance and reliever therapy vs. conventional best practice in asthma management.

A comparison of budesonide/formoterol maintenance and reliever therapy vs. conventional best practice in asthma management.

The patient's perception of asthma control, weekly symptoms and activity limitation assessed by a validated asthma control questionnaire (ACQ5) was improved to a greater extent over the study period with Budesonide/formoterol SMART than with CBP, although the two groups of patients were equally satisfied with their treatment at the end of the study. Of note is the fact that more than 95% of the patients did not change the maintenance treatment in the CBP group despite the fact that ACQ5 was > 0.75 for most of the patients. However this trial was undertaken 1 year before the publication of the GINA that recommended the use of ACQ in clinical practice to assess asthma control and adjust the treatment accordingly. That might explain the relative passivity of the doctors in adjusting the dose of maintenance treatment based on ACQ value.
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Best Practice Recommendations for the Development, Implementation, and Evaluation of Online Knowledge Translation Resources in Rehabilitation

Best Practice Recommendations for the Development, Implementation, and Evaluation of Online Knowledge Translation Resources in Rehabilitation

therapists in stroke rehabilitation because they incorporate motor learning principles of task-oriented, challenging, and motivating practice. However, clinicians face challenges when integrating VR into clinical practice, including limited availability of training that supports the implementation of VR-based therapy with a motor learning focus. This project created online learning resources to promote motor learning– based integration of GestureTek’s IREX and Gesture Xtreme systems into clinical practice. The 3 e-learning modules provide foundation knowledge about evidence for VR use in neurorehabilitation, neuroplasticity, motor learning principles, IREX/GX game characteristics, setting SMART goals, and implementing motor learning strategies. As a component of a larger knowledge translation initiative, the modules led to improvements in therapists’ behavioral control, self-efficacy, and VR knowledge.
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Design of a best-practice start-up accelerator for the Granada Health Technology Park

Design of a best-practice start-up accelerator for the Granada Health Technology Park

Program Length Acceptance Rate Key Intangible Value Seed Capital Equity Stake Required Main Success Metric For profit 5 months N/A Network, follow up funding, access to Telefonica VC[r]

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View of Is Brand Name Best? Brand name versus generic pharmaceuticals in clinical practice

View of Is Brand Name Best? Brand name versus generic pharmaceuticals in clinical practice

1 Faculty of Medicine, Univeristy of Ottawa INTRODUCTION It’s a common scenario: standing in front of the cereal isle de- bating between ‘Cheerios’ and the less-than-appealing ‘Toasted Oat’ generic version. Sure, Cheerios is the original and has that ever persuasive bee on the box, but the generic is superior in terms of cost. Of course, the generic tastes about the same, but depending on the store, the generic version is slightly different– nothing compares to the consistency of a bowl of tried and true Cheerios. A similar decision is made by physicians when deciding between brand name medications and generics. Since 2010, sev- eral ‘blockbuster drugs’, which are drugs that make pharmaceuti- cal companies billions of dollars, have lost their patents [1]. This phenomenon is commonly referred to as the ‘patent cliff’ [1]. As another ‘patent cliff’ is set to occur from 2014 to 2020 [1], we will see generic manufacturers take over the production of brand name medications at a fraction of the cost. For example, 2015 saw Abilify, a popular antipsychotic, and Lantus, a long-acting in- sulin, lose their patents [1]. What does this mean for patients? Are brand name drugs clinically superior? How are generic and brand name drugs licenced and what does this mean in terms of their efficacy and potency? This commentary will highlight the differences between brand name and generic drugs that pre- scribers may want to consider before putting pen to prescription pad.
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Diagnosis and management of adult female stress urinary incontinence: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians.

Diagnosis and management of adult female stress urinary incontinence: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians.

3.3 Association or urinary incontinence and pelvic organ prolapse Pelvic organ prolapse commonly coexist with lower urinary tract symptoms such as stress urinary incontinence, urge incontinence, or obstructive symptoms. Urge incontinence or obstruction resolve in one out of two cases when the prolapse is corrected {LE2}. Pelvic organ prolapse may mask stress urinary incontinence in a proportion of women ranging from 20% to 70% of cases {LE3}. In women presenting with pelvic organ prolapse without stress urinary incontinence, rate of urodynamic stress incontinence detection is lower with pessary than with speculum prolapse reduction {LE1}. The pessary test has also been suggested to predict the result of prolapse surgery on urinary symptoms. In this indication the predictive value of the pessary test remains unclear {LE3}, and it is not recommended to use it routinely {Grade C}. A positive cough test and the screening of occult stress incontinence may identify patients with an increased risk of postoperative stress incontinence who could benefit from a concomitant anti-incontinence procedure at the time of pelvic organ prolapse surgery {LE4}. It is recommended to carry out a cough test and look for occult incontinence prior to surgery for pelvic organ prolapse {Grade C}. The preoperative urodynamic investigation has a predictive value for the postoperative risk of urge incontinence or voiding dysfunction in case of pelvic organ prolapse surgery {LE4}. It is recommended to carry out urodynamic investigations prior to pelvic organ prolapse surgery when there are urinary symptoms or occult urinary incontinence {Grade C}.
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