splice variant
β1D integrin splice variant stabilizes integrin dynamics and reduces integrin signaling by limiting paxillin recruitment
... integrin splice variant demonstrates a higher affinity for the talin2 adapter protein, but at the expense of failing to support de novo FN fiber assembly, as well as failing to induce integrin-dependent ...
25
Study of a new splice variant of Neuropilin-1: antagonistic functions in the regulation of cancer progression?
... new splice variant of Neuropilin-1: antagonistic functions in the regulation of tumor progression? Introduction Neuropilin-1 (NRP1) is a transmembrane glycoprotein and a co-receptor for several soluble ...
1
The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma
... We provide here the first description of sVEGFR1-i13 protein expression in NSCLC patients. We find that high levels of both sVEGFR1-i13 and β1 integrin proteins correlate with high levels of P-VEGFR1(Tyr1213) as well as ...
14
A Splice Variant in SLC16A8 Gene Leads to Lactate Transport Deficit in Human iPS Cell-Derived Retinal Pigment Epithelial Cells
... gene; (B) position of the primers used to study the splicing of the gene in iRPE cell lines; (C) RT-PCR analysis of SLC16A8 gene splicing, revealing intron retention for the iRPE cell li[r] ...
17
VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loop
... Compared to SCC cell lines, most ADC cell lines expressed higher levels of intra-cellular (Supplementary Figure 1c) or circulating (Supplementary Figure 1d) VEGF 165 b prot[r] ...
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Alternative Splicing of TAF6: Downstream Transcriptome Impacts and Upstream RNA Splice Control Elements
... TAF6d splice variant versus the major TAF6a splice ...TAF6d splice variant was originally cloned from a HeLa cell cDNA library ...expected splice products ...
16
TP53 drives invasion through expression of its Δ133p53β variant
... D133p53 isoforms control breast cancer cell invasion To address the role of mutant D133p53 isoforms in the enhanced invasiveness of MDA-MB-231 D3H2LN cells, we analyzed cells depleted either of all D133p53 isoforms (by ...
27
FAK alternative splice mRNA variants expression pattern in colorectal cancer
... 28 splice variant, including exon 13 coding for a peptide fragment of 28 amino acids (box 28), juxtaposed in N-terminal to the box 6 7 displays a pattern of progressive increased expres- sion toward ...
10
A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.
... 1 Unit of Animal Genomics, GIGA-R and Department of Animal Sciences, Faculty of Veterinary Medicine, University of Lie`ge, Lie`ge, Belgium, 2 Unit of Bioinformatics, Department of Animal Sciences, Faculty of Veterinary ...
10
A Spatially Variant Rebalancing Method forDiscrete-Ordinates Transport Equation
... Abstract In this paper we propose a new non-linear technique for accelerat- ing source iterations for the discrete-ordinates transport equation. The method, called Spatially Variant Rebalancing Method (SVRM), is ...
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Étude d'un variant de la toxine STb produite par Escherichia coli
... and variant STb were adjusted to ...and variant; ~5200 Da) and sulfatide (SFT) (~794 kDa; Sigma, Oakville, ON) was examined using a BIACORE 3000 system (GE Healthcare Bio-Sciences AB, Uppsala, ...
113
Novel CAPN3 variant associated with an autosomal dominant calpainopathy
... CAPN3 variant was not initially considered as disease-causing due to the absence of a second CAPN3 ...CAPN3 variant with that novel transmission mode [9] ...
16
RNA-Guided Genomic Localization of H2A.L.2 Histone Variant
... Despite this cautionary note, the preferential accumulation of H2A.L.2 in the pericentric regions is strongly supported by the remarkable property of H2A.L.2, which is capable of targeting pericentric regions upon its ...
15
On the odd-minor variant of Hadwiger's conjecture
... Hamilton Cycle is the special case of Odd H-Expansion where H is a cycle with the same number of vertices as G; Vertex Cover by Triangles is the special case of k Odd Disjoint Cycles whe[r] ...
15
A variant of the Erdős‐Sós conjecture
... If we greedily embed a tree with m edges in such a graph by embedding the vertices in breadth-first order, treating all the children of each vertex as a consecutive block, we see that fo[r] ...
32
Restoration Method for Spatially Variant Blurred Images
... Abstract: Most of existing image restoration techniques suppose that the blur is spatially-invariant. However, various physical phenomena related to the optical instrument properties make that degradations may change in ...
36
Service Querying to Support Process Variant Development
... Abstract Developing process variants enables enterprises to effectively adapt their business models to different markets. Existing approaches focus on business process models to support the variant development. ...
45
On a variant of Newton-Coulomb's law
... simple variant of the Newton-Coulomb potential which has two properties: near the singularity the attractive force becomes repulsive, and for large distances the attraction is slighter stronger than the force ...
9
Formation d’hydrates sans et avec additif antiagglomérant en variant le débit et la fraction d’eau
... FORMATION D’HYDRATES SANS ET AVEC ADDITIF ANTIAGGLOMÉRANT EN VARIANT LE DÉBIT ET LA FRACTION D’EAU A.M. MELCHUNA a,* , A. CAMEIRAO a , J.M. HERRI a , P. GLENAT b a Ecole Nationale Supérieure des Mines de ...
2
On a variant of Schanuel conjecture for the Carlitz exponential
... Although at first sight, our interest in this framework may seem rather artificial (why looking at an analogue conjecture while we already have so many interesting open problems in the f[r] ...
30