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Second-Line Treatment

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer

Safety and efficacy of temsirolimus as second line treatment for patients with recurrent bladder cancer

... highest treatment costs [ 4 ...the treatment of choice for non-muscle-invasive bladder cancers and cystectomy is used for non-metastatic forms of muscle invasive tumors [ 7 ...as second line ...

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Qualitative study of patients’ decision-making when accepting second-line treatment after failure of first-line chemotherapy

Qualitative study of patients’ decision-making when accepting second-line treatment after failure of first-line chemotherapy

... “I actually do not doubt, should I say that? . . . I trust the doctor completely. If he decides that he should change the treatment for such or such reason. . .well. . . we discuss it. Some- times I give up. But ...

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A phase I-trial assessing several schedules of Oral S-1 combined with fixed doses of Oxaliplatin and Irinotecan in patients with advanced or metastatic digestive adenocarcinoma as first- or second-line treatment

A phase I-trial assessing several schedules of Oral S-1 combined with fixed doses of Oxaliplatin and Irinotecan in patients with advanced or metastatic digestive adenocarcinoma as first- or second-line treatment

... A phase I-trial assessing several schedules of Oral S-1 combined with fixed doses of Oxaliplatin and Irinotecan in patients with advanced or metastatic digestive adenocarcinoma as first-[r] ...

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Fluropyrimidine single agent or doublet chemotherapy as second line treatment in advanced biliary tract cancer

Fluropyrimidine single agent or doublet chemotherapy as second line treatment in advanced biliary tract cancer

... ABSTRACT Fluoropyrimidine (FP) plus platinum chemotherapy has been recently established as a second- line (L2) preferred option in advanced biliary tract cancer (aBTC) (ABC-06 phase III trial). However, ...

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PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer

PRODIGE 59-DURIGAST trial: A randomised phase II study evaluating FOLFIRI + Durvalumab ± Tremelimumab in second-line of patients with advanced gastric cancer

... DURIGAST is a randomised, multicenter, non-comparative, phase II study, evaluating safety and efficacy of FOLFIRI plus Durvalumab (anti-PD-L1) versus FOLFIRI plus Durvalumab and Tremelimumab (anti-CTLA-4) as ...

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A randomized phase II pharmacokinetic and pharmacodynamic study of indisulam as second-line therapy in patients with advanced non-small cell lung cancer

A randomized phase II pharmacokinetic and pharmacodynamic study of indisulam as second-line therapy in patients with advanced non-small cell lung cancer

... these treatment schedules has single-agent activity as second-line treatment of non -small cell lung ...which treatment is palliative. First-line platinum-based chemotherapy ...

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Cost-Effectiveness of Three Alternative Boosted Protease Inhibitor-Based Second-Line Regimens in HIV-Infected Patients in West and Central Africa.

Cost-Effectiveness of Three Alternative Boosted Protease Inhibitor-Based Second-Line Regimens in HIV-Infected Patients in West and Central Africa.

... optimal second-line therapy. Second, the structure of the simulated patient-level Markov model and the defini- tion of heath states were constrained by the size of the study population, which was too ...

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Positive Virological Outcomes of HIV-Infected Patients on Protease Inhibitor-Based Second-Line Regimen in Cambodia: The ANRS 12276 2PICAM Study

Positive Virological Outcomes of HIV-Infected Patients on Protease Inhibitor-Based Second-Line Regimen in Cambodia: The ANRS 12276 2PICAM Study

... reported treatment failure, defined as the first diagnosis of clinical, immunological or viro- logical failure, for 19% of patients receiving PI-based second-line therapy for more than 6 months ...

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Socio-economic status influences access to second-line disease modifying treatment in Relapsing Remitting Multiple Sclerosis patients

Socio-economic status influences access to second-line disease modifying treatment in Relapsing Remitting Multiple Sclerosis patients

... France, second-line DMT initiation is strictly reserved to public or private hospital neurological ...receive second-line DMT only in hospital, at least regarding initiation, and are mainly ...

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équations du second degré

équations du second degré

... On se propose de résoudre par une construction géométrique toute équation du second degré. Les seules notions nécessaires sont : équations de droite, droites orthogonales, cercles et équation du second ...

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Line-by-line spectroscopic simulations on graphics processing units

Line-by-line spectroscopic simulations on graphics processing units

... Fig. 4. Description of data generation on the host and temperature and pressure corrections in the first steps of the graphics pipeline. visible but partially hidden or seen through other objects. This process ends with ...

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On-line / l'Histoire branchée

On-line / l'Histoire branchée

... Tout en poursuivant ce travail d’indexation pour des références antérieures à 1982, nous procédons à la mise à jour de la base de données bibliographiques deux fois par année, au printem[r] ...

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Virological outcome among HIV-1 infected patients on first-line antiretroviral treatment in semi-rural HIV clinics in Togo

Virological outcome among HIV-1 infected patients on first-line antiretroviral treatment in semi-rural HIV clinics in Togo

... 1. Gilks CF, Crowley S, Ekpini R, Gove S, Perriens J, Souteyrand Y, et al. The WHO public‑health approach to antiretroviral treatment against HIV in resource‑limited settings. Lancet. 2006;368:505–10. 2. Aghokeng ...

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Second-Order Beliefs and Second-Order Expected Utility

Second-Order Beliefs and Second-Order Expected Utility

... First-Stage Independence. For any α ∈ (0, 1] and lotteries P, Q, R ∈ L(H), αP + (1 − α)R  αQ + (1 − α)R ⇐⇒ P  Q. As before, the interpretation of the First-Stage Independence axiom becomes transparent when the mixture ...

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On-line vertex-covering

On-line vertex-covering

... Laboratoire d'Analyse et Modélisation de Systèmes pour l'Aide à la Décision CNRS UMR 7024.. On-line vertex-covering Marc Demange, Vangelis Th.[r] ...

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On the Interoperability of DEVS components: On-Line vs. Off-Line Strategies

On the Interoperability of DEVS components: On-Line vs. Off-Line Strategies

... independent manner - minimum requirements for a simulator to be labeled "DEVS-compliant" - model libraries, aimed at providing a collection of models usable out of the box This paper focuses on the second ...

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Line Directed Hypergraphs

Line Directed Hypergraphs

... Hypergraphs, Line Hypergraphs, De Bruijn and Kautz net- works, Connectivity 1 Introduction In the beginning of the 80’s one of the authors - JCB - started working on the design of bus networks in order to answer a ...

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Line shift, line asymmetry, and the 6Li/7Li isotopic ratio determination

Line shift, line asymmetry, and the 6Li/7Li isotopic ratio determination

... reinforcement of the red wing of each component of the corresponding 7 Li line, with respect to its blue wing. Aims. The present paper studies the halo star HD 74000 and estimates the impact of convection-related ...

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Bayesian estimates of transmission line outage rates that consider line dependencies

Bayesian estimates of transmission line outage rates that consider line dependencies

... 4 line outage rates with the data available after the 1st year, after the 7th year, and after the 14th ...I, line 29 has no outage except in the 9th and 10th ...of line 29 for the 1st year is ...

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A frequency divider from 100 kilocycles/second to 60 cycles/second

A frequency divider from 100 kilocycles/second to 60 cycles/second

... L’accès à ce site Web et l’utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D’UTILISER CE SITE WEB. NRC Publicat[r] ...

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