Mitochondrial protein
![Impact of mutations within the [Fe-S] cluster or the lipoic acid biosynthesis pathways on mitochondrial protein expression profiles in fibroblasts from patients](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
Impact of mutations within the [Fe-S] cluster or the lipoic acid biosynthesis pathways on mitochondrial protein expression profiles in fibroblasts from patients
... Impact of mutations within the [Fe-S] cluster or the lipoic acid biosynthesis pathways on mitochondrial protein expression profiles in fibroblasts from patients E. Lebigot, P. Gaignard, I. Dorboz, A. Slama, ...
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The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells
... of mitochondrial protein import by the PINK1/Parkin ...facilitate mitochondrial protein import ...in mitochondrial abundance (Supplementary ...
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In Silico Survey of the Mitochondrial Protein Uptake and Maturation Systems in the Brown Alga Ectocarpus siliculosus
... Supporting Information Figure S1 Alignments of conserved regions of predicted Ectocarpus mitochondrial proteins with the correspond- ing regions from their eukaryotic homologues. (A) Alignment of Tom7 proteins ...
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Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)
... the mitochondrial genome may occur faster than that in nuclear ...repair mitochondrial damage promptly and ...any mitochondrial protein interacts with ...
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Fast digestive, leucine-rich, soluble milk proteins improve muscle protein anabolism and mitochondrial function in undernourished old rats
... myofibrillar protein and mitochondrial protein synthesis provide a theoretical basis for the sarcopenia of ...dietary protein activation of the translational regulators, ...muscle ...
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Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss
... mitochondria (Figure 3a). To confirm the localization of the human ND4 in the mitochondrial compartment, antibodies against the mitochondrial protein ND6 (a CI subunit) and the HA1 epitope were ...
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Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease
... modified protein [22, ...brain mitochondrial Lon protease can be inhibited by peroxynitrite in vitro ...impair mitochondrial protein involved in mitochondria quality control, such as a ...
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Two distinct membrane potential–dependent steps drive mitochondrial matrix protein translocation
... -mediated mitochondrial translocation • Schendzielorz et ...that mitochondrial matrix proteins do not display a uniform dependency on ...of mitochondrial protein ...
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A Yeast Mitochondrial Membrane Methyltransferase-like Protein Can Compensate for $oxa1$ Mutations
... Members of the Oxa1p/Alb3/YidC family mediate the insertion of various organelle or bacterial hydrophobic proteins into membranes. They present at least five transmembrane segments (TM) linked by hydrophilic domains ...
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Mitochondrial trifunctional protein deficiency in human cultured fibroblasts: effects of bezafibrate
... a mitochondrial/cytosol fractionation kit (Abcam, Cambridge, UK) according to the manufacturer’s ...prepare protein extracts. 25µg of total protein or 15 µg of mitochondrial protein per ...
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L’ADN mitochondrial, un potentiel codant mésestimé
... génome mitochondrial, à l’intérieur de la séquence de l’ARNr 16S [13] ...16S mitochondrial suggère en effet que, d’une part, un ARNm soit issu de ce transcrit, normalement déjà engagé dans la constitution ...
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Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains
... to mitochondrial dysfunctions, we used the neuroblastoma stable and inducible cell line expressing C99 fragment only [ 45 ...in mitochondrial-enriched fraction prepared from C99-expressing cells as compared ...
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Instabilité du génome mitochondrial et pathologies associées
... > Parmi les maladies mitochondriales, un certain nombre sont caractérisées par une instabilité du génome mitochondrial qui se manifeste par la présence de délétions multiples ou de déplé- tions de ce génome. ...
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Mass Spectrometry of Mitochondrial Membrane Protein Complexes
... particular, mitochondrial oxidative phosphorylation, which produces ATP, the energy source of the cell, involves five respiratory complexes called also OXPHOS that are inserted in the inner mitochondrial ...
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Caffeine Sensitizes Human H358 Cell Line to p53-mediated Apoptosis by Inducing Mitochondrial Translocation and Conformational Change of BAX Protein
... the protein in both p53-null cells, that do not die upon caffeine exposure, and p53-expressing cells, in which caffeine triggers cell ...Peg3/Pw1 protein, which induced BAX translocation from cytosol to ...
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Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons
... 4.4. Immunocytochemistry Cultured mesencephalic neurons were fixed for immunocytochemistry at 12 DIV. Following fixation with 4% paraformaldehyde for 30 min, they were incubated with 0.1% Triton X-100 for 15 min. After ...
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Effets de la température sur le métabolisme mitochondrial cardiaque
... Les différences de composition en acides gras des membranes mitochondriales cardiaques n'ont cependant pas engendré de différences au niveau de la respiration mitoc[r] ...
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Effets de la température sur le métabolisme mitochondrial cardiaque
... composition en acides gras des membres mitochondriales cardiaques de rat, nous n'ayons pas décelé de changements au niveau de la respiration mitochondriale ou de sa thermos[r] ...
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Pathologies de l’ADN mitochondrial et stratégies thérapeutiques
... génome mitochondrial muté, un des prérequis est la présence d’un site de restriction qui lui est ...d’import mitochondrial peut être adressée aux mitochondries, où elle clivera spécifiquement l’ADNmt mutant ...
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In silico analysis of mitochondrial proteins
... As a large number of complete genome sequences from prokaryotes and eukaryotes have become available, large-scale subfamily classification and phylogenetic ana- lysis of the ACAD family are now tractable. Our first step in ...
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