liver metastases
High-intensity focused ultrasound ablation for the treatment of colorectal liver metastases during an open procedure: study on the pig.
... the liver to 9 cm in ...deep liver metastases in human without any ...the liver using an ultrasound sterile cooling and coupling liquid (Ablasonic®, Edap- Technomed, Vaulx en Velin, France) ...
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Replacement and desmoplastic histopathological growth patterns: A pilot study of prediction of outcome in patients with uveal melanoma liver metastases
... the liver within 10 years of diagnosis, and these almost always prove rapidly ...of liver metastases of the replacement and desmoplastic type, particularly from colon and breast carcinoma, may import ...
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Lobulated enhancement evaluation in the follow-up of liver metastases treated by stereotactic body radiation therapy
... in liver metastases treated by SBRT for 2 reasons. First, liver metastases that are eligible for SBRT in our study have already been modified by previous chemotherapy and thus do not show ...
8
Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
... Recently, liver metastases from pancreatic cancer have been reported to be desmoplastic with high concentrations of HA and collagen that correlated with patients’ survival ...
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Spatial modelling of tumour drug resistance: the case of GIST liver metastases Mathematical Medicine and Biology Advance
... First, an important variability exists in the molecular and genetic characteristics that drive the patho- genesis of these tumours. Hirota et al. ( 1998 ) have proved that molecular alterations in KIT gene with ...
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TGF-B induced protein IG-H3 is essential for the growth of human liver metastases
... Methods &Results : CRC-LM and in liver metastases originating from breast, lung and pancreatic tumors. We have next focused on func- tional aspects and have silenced TGFBI expression in SW1222 human ...
1
Postoperative hepatic arterial chemotherapy in high-risk patients as adjuvant treatment after resection of colorectal liver metastases - a randomized phase II/III trial – PACHA-01 (NCT02494973)
... colorectal liver metastases (CRLM), liver recurrence occurs in more than 60% of patients, despite the administration of perioperative or adjuvant ...
9
Development of Targeted Therapies for Liver Metastases: Is Heterogeneity a Major Issue?
... of liver metastasis from colorectal carcinoma ...CRC-liver metastases and divided the specimen in 4 zones: normal, peri-tumoral, tumor-rim and ...
1
Chronological occurrence of PI3KCA mutations in breast cancer liver metastases after repeat partial liver resection
... Results: The two major somatic hot spot PI3KCA mutations were found in 27 (38.6%) nodules corresponding to 8 of the 19 patients (42%). The frequency of women whose breast cancer liver metastases (BCLM) ...
8
Liver transplantation for irresectable colorectal liver metastases: still a contraindication?
... Liver transplantation (LT) for irresectable colorectal cancer liver metastases (i-CRLM) has been considered up to now an absolute contraindication due to unfavorable outcomes, scarcity of grafts and ...
5
Adjuvant Radioimmunotherapy Trial with Iodine-131-Labeled Anti-Carcinoembryonic Antigen Monoclonal Antibody F6 F(ab')2 after Resection of Liver Metastases from Colorectal Cancer.
... the therapeutic dose. Patient 12 (TTL ratio of 2) was considered to be at high risque of recurrence and no other adjuvant therapy could be offered at that time. Patients 7 and 13 did not receive the pre-operative ...
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Efficacy of high-intensity focused ultrasound-assisted hepatic resection (HIFU-AR) on blood loss reduction in patients with liver metastases requiring hepatectomy: study protocol for a randomized controlled trial
... Preclinical study has demonstrated that HIFU-AR using the new toroidal-shaped transducer during an open procedure in an animal model is safe, reduces bleeding, and can be guided by real-time ultrasound imaging. This work ...
11
Utility of Image Guidance in the Localization of Disappearing Colorectal Liver Metastases
... There are several limitations to the present study. First, this was not conducted in a blinded setting as the same primary surgeon performed both the initial US as well as the subsequent US with image guidance; however, ...
14
A Mathematical Model for Growing Metastases on Oncologists’s Service
... angiogenic factors after emoval of primary colorectal carcinoma coincides with increased metabolic acticity of liver metastases. Surgery. 137: 246-249. 11. Verga F, You B, Benabdallah A, Hubert F, Faivre C, ...
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Incidence of brain metastases in HER2+ gastric or gastroesophageal junction adenocarcinoma.
... had liver metastases, 32 (51%) lymph node metastases, 20 (32%) peritoneal carcinomatosis, 12 (19%) lung metastases and 3 (5%) brain ...
10
Treatment intensification with hepatic arterial infusion chemotherapy in patients with liver-only colorectal metastases still unresectable after systemic induction chemotherapy -a randomized phase II study --SULTAN UCGI 30/PRODIGE 53 (NCT03164655)-study protocol
... Since liver metastases mainly receive blood supply from the hepatic artery whereas normal liver tissue is primar- ily perfused by the portal vein, hepatic arterial infusion (HAI) was developed to ...
12
Understanding the Progression of Bone Metastases to Identify Novel Therapeutic Targets
... cancer metastases, particularly for prostate, breast, kidney, lung and thyroid primary ...bone metastases progression, and therefore of novel therapeutic ...
21
Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout
... in liver tissue from AlfpCre +/0 ;Rosa26R +/0 mice indicates Cre-lox-recombinant ...wild-type liver (left ...from liver RNA was however not ...
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en fr PRECLINICAL EVALUATION OF NEW THERAPIES TARGETING OSTEOCLASTS IN THE BREAST CANCER ASSOCIATED BONE METASTASES TREATMENT. ÉVALUATION PRECLINIQUE DE NOUVELLES THERAPIES CIBLANT LES OSTEOCLASTES DANS LE TRAITEMENT DES METASTASES OSSEUSES DU CANCER DU SEIN.
... We next compared the effects of the different dosing regimens of zoledronic acid and the daily dosing regimen of clodronate on the formation of breast cancer bone metastases by using a[r] ...
157
Patient selection for laparoscopic excision of adrenal metastases: a multicenter cohort study
... Variables collected included patients’ characteristics (age, gender, ASA score, Body Mass Index), tumor related data (primary tumor, size, laterality, synchronous or metachronous, isolated or oligometastatic disease, ...
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