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A framework for an evidence-based gene list relevant to autism spectrum disorder

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Academic year: 2021

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Figure

Table 2. Scoring outcome in 11 exemplary genes
Fig. 1. Overlap between three sets of genes considered to be associated with ASD susceptibility
Fig. 2. Proposed pipeline. Step 1, Evidence curation to evaluate strength of a gene-disease relationship based  on  publicly  available  genetic  and  experimental  evidence
Fig  3.  Systematic  evaluation  of  quality  of  the  ASD  phenotype  report.  Six  phenotype  experts  independently  scored eight published reports 100-107  using this algorithm; results indicated 98% consistency regarding the rating  of  low,  medium

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