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Nonlinear microbubble behaviour for enhanced drug uptake

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Academic year: 2021

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Figure

Figure 1 shows the setup used to simultaneously observe and sonicate the cells. A signal con- con-sisting of 50 cycles with a centre frequency of 6.6 MHz and a pulse repetition frequency of 10 kHz, i.e.
Figure 2. Typical sonoporation event showing two microbubbles translate into a HeLa cell and subsequently dissolving (top) and graphical representation (bottom).
Figure 3. Schematic representation of the five physical mechanisms supposedly involved in sonoporation.

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