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CO and CO-releasing molecules in medicinal chemistry

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Academic year: 2021

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Figure

Figure 1. x-ray structures of human heme oxygenases 1 and 2 and their  catalyzed heme degradation
Figure 2. Structures of selected well-known CO-releasing molecules. In  these examples ‘R’ indicates an organic substituent and ‘L’ a monodentate ligand
Table 2. Chemical properties and major biological effects of selected CO-releasing molecules.
Figure 3. Possible reactions resulting in the CO loss from a CO-releasing  molecule of general formula [(CO) 3 ML 1 L 2 L 3 ]
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