Core protein domains involved in hepatitis C virus-like particle assembly and budding at the endoplasmic reticulum membrane.

L'infection postopératoire est rare en chirurgie thyroïdienne (0,5 %) [104]. La plupart du temps, elle ne se manifeste que quelques jours après la sortie, et une évacuation

Phosphorylation of the Arginine-Rich C-Terminal Domains of the Hepatitis B Virus (HBV) Core Protein as a Fine Regulator of the Interaction between HBc and Nucleic

However, early studies of cells infected with the JFH-1 virus showed that the core protein was detected at the surface of lipid droplets or in association with the ER membranes

25-27 Although this cellular model is based on HCV core protein production from a genotype 1a virus, it also displays the accumulation and clustering of lipid droplets

For cells expressing wild-type HBc (Fig. 5G; yellow dots), most of the measurements showed that this protein was essentially in an oligomeric form, and this even at low protein

This phenomenon was observed in the hepatoma cell line Huh7 infected with the complete virus (the JFH-1 strain), but also in Huh7 cells producing only the mature HCV core

Moreover, an absence of core protein at the LD sur- face was associated with higher levels of virus secretion for the C10M-JFH-1 construct than for the wt-JFH-1 construct,

We have developed a model based on Semliki forest virus (SFV) replicon vectors, in which the production of the HCV core protein in mammalian cells leads to the