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HAL Id: tel-01260929

https://tel.archives-ouvertes.fr/tel-01260929

Submitted on 22 Jan 2016

HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci-entific research documents, whether they are pub-lished or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers.

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Caractérisation des souris CHMP2Bintron5, un modèle

d’étude du continuum SLA-DFT

Aurelia Vernay

To cite this version:

Aurelia Vernay. Caractérisation des souris CHMP2Bintron5, un modèle d’étude du continuum SLA-DFT. Biologie moléculaire. Université de Strasbourg, 2014. Français. �NNT : 2014STRAJ116�. �tel-01260929�

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Figure

Figure 1.Increased mitochondrial DNA levels in Cramping mice. +/+ mice are in blue columns, Cramping mice are in red columns
Figure 2. Transcriptional activation of PGC-1a isoforms in Cramping mice.
Figure 4. FL-PGC-1a ablation exacerbates global phenotype of Cramping mice. +/+ mice are in blue, Cramping mice in red, FL-PGC-1a2/2 in green and com- com-poundCra/FLa2/2 in brown
Figure 5. FL-PGC-1a ablation exacerbates mitochondrial dysfunction in Cramping mice. Representative photomicrographs showing muscle sections of +/+, Cramping, PGC-1a1/4 2/2 and compound Cra/FLa2/2 tibialis anterior (upper pictures) and soleus muscles from
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