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Effect of intracortical vascular endothelial growth factor infusion and blockade during the critical period in the rat visual cortex

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Technique Principal quantitative results

Ca n n ul a p la cem en t EBA VEGF group showed a diminished lesion area and lesser protein extravasation compared to aVEGF and vehicle groups

GFAP VEGF group showed higher astrocytic density than aVEGF group (IL and CL)

P ri m a ry v is u a l co rt ex

Butyryl cholinesterase VEGF group showed higher vascular density than aVEGF and vehicle groups (IL and CL)

NeuN

VEGF group showed higher neuronal density than aVEGF group (IL)

VEGF group showed a higher neuronal density than aVEGF and vehicle groups (CL)

Tunel VEGF administration reduces apoptotic cell density (IL and CL)

WB (VEGF) VEGF group showed higher VEGF level than aVEGF group

Table 1. Summary of statistically significant results in cannula placement area (EBA, GFAP) and in primary visual cortex (Butyryl Cholinesterase, NeuN, Tunel, WB). IL: ipsilateral cortice; CL:

contralateral cortice.

Published in "Brain Research 1473: 141–154 , 2012"

which should be cited to refer to this work.

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