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Thaliadb : A database dedicated to association genetic in plants

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HAL Id: hal-02417594

https://hal.archives-ouvertes.fr/hal-02417594

Submitted on 18 Dec 2019

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Thaliadb : A database dedicated to association genetic in plants

Yannick de Oliveira, Guy-Ross Assoumou-Ella, Alain Charcosset, Johann Joets

To cite this version:

Yannick de Oliveira, Guy-Ross Assoumou-Ella, Alain Charcosset, Johann Joets. Thaliadb : A database dedicated to association genetic in plants. European Conference on Computational Biol- ogy 2014, Sep 2014, Strasbourg, France. �hal-02417594�

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Thaliadb : A database dedicated to association genetic in plants

Yannick de Oliveira, Guy-Ross Assoumou-Ella, Alain Charcosset and Johann Joets INRA, UMR 8120 Génétique Végétale, F-91190 Gif-sur-Yvette, France

Diversity and association genetics studies lead to manipulate a large number of individual, lines, clones and/or populations. Moreover, emergence of high-throughput technologies for both genotyping and phenotyping

generates a large amount of data. These need to be stored and managed in order to perform requests and organize datasets to conduct association genetics studies.

The Thaliadb database has been developed with this aim. It manages genetic resources, phenotyping and

genotyping data, and also population structure information. Thalia enables data extraction in formats used by genetic association software.

Database structure Data export and visualization

Seed lot Vgt1 MITE A Vgt1 MITE B Days to

pollen Northern flint Andes Caribbean Corn belt

dent Europe Mexican Italian

PPS48 0,00 1,00 57,9 0,9140 0,0104 0,0088 0,0092 0,0162 0,0106 0,0308

PI217460 0,21 0,79 72,3 0,9156 0,0056 0,0088 0,0412 0,0084 0,0096 0,0110

PI218143 0,52 0,48 85,8 0,0852 0,0178 0,0164 0,6516 0,0178 0,2016 0,0088

PI213719 0,80 0,20 81,8 0,0810 0,0136 0,0268 0,8024 0,0150 0,0204 0,0410

PPS774 1,00 0,00 77,2 0,0090 0,0664 0,2494 0,0174 0,0410 0,0898 0,5274

Main projects involving Thaliadb

Thaliadb has been developed using the Postgresql database management system. Recently, we migrate a part of the database in the MongoDB system. Thus, performances has been improved and Thaliadb is now able to manage the data produced by high-throughput technologies.

F. Tardieu & al.

A. Charcosset & al.

Thaliadb is available at the url : http://thalia.moulon.inra.fr

The aim of GnpAsso project was to develop generic tools to manage and exploit results from association genetics studies. Thaliadb is integrated with the SNiPlay pipeline to process genotype datasets.

New functionalities has been developed in Thaliadb to export data to

GnpAsso database. GnpAsso D. Steinbach & al.

A. Dereeper & al.

DROPS aims at developing novel methods and strategies for genetic yield improvement under dry environments and for enhanced plant water-use efficiency.

In this project, we are developing a web service to allow user request Thaliadb through DROPS application

Amaizing aims to identify markers and candidate genes responsible for traits of agronomic interest such as yield, quality and tolerance to abiotic stress.

The project aims also to develop breeding methods for creation of new varieties of improved maize. The web service of Thaliadb and the functionalities dedicated to high-throughput data will be improved

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