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Figure

Figure S1A). For the analysis of the CD4+ T cells of RA cases and controls, we fit a simpler binomial regression model without including additional covariates for  smok-ing, cell types, or sex, due to the sample size available.
Fig. 1 Genome-wide distribution of significant CpG sites from EWAS analysis. a qq-plot of the p values from the EWAS associations between ACPA-positive and ACPA-negative after adjustment for cell-type heterogeneity
Fig. 2 EWAS analysis in ACPA-measured subjects, self-reported RA patients, and dose-dependent DNA methylation analysis
Fig. 3 Results of genomic element enrichment analysis of ACPA-associated DMRs. a Genome feature enrichment analysis
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