Astrocytic TSPO Upregulation Appears Before Microglial TSPO in Alzheimer's Disease

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Intracranial IL-17A overexpression decreases cerebral amyloid angiopathy by upregulation of ABCA1 in an animal model of Alzheimer’s disease... 1 Intracranial IL-17A

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Its cellular origin demonstrated in the brain in microglia, although it is clear that other cell types also express TSPO and its presence in astrocytes and endothelial cells is now

Conversely, the presence of cell death in response to Tau and A β is independent of TSPO alteration (polymerization and density), suggesting that TSPO in Alzheimer ’ s disease

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