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Cancer colorectal et viande rouge : les produits dérivés de la lipoperoxydation induisent différentes réponses d'apoptose, d'autophagie et de Nrf2 dans des cellules coliques normales et prénéoplasiques

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HAL Id: tel-01514172

https://tel.archives-ouvertes.fr/tel-01514172

Submitted on 25 Apr 2017

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Cancer colorectal et viande rouge : les produits dérivés

de la lipoperoxydation induisent différentes réponses

d’apoptose, d’autophagie et de Nrf2 dans des cellules

coliques normales et prénéoplasiques

Reggie Surya

To cite this version:

Reggie Surya. Cancer colorectal et viande rouge : les produits dérivés de la lipoperoxydation induisent différentes réponses d’apoptose, d’autophagie et de Nrf2 dans des cellules coliques normales et prénéo-plasiques. Toxicology and food chain. Université Paul Sabatier - Toulouse III, 2016. English. �NNT : 2016TOU30082�. �tel-01514172�

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Figure

Figure 1.  Fecal water of Hb- and Bf-fed rats (Hb and Bf) exerted higher toxicity towards normal cells compared with preneoplastic cells
Figure 2.  Carbonyl-trapping resin (CTR) was shown to be effective in depleting carbonyl compounds (including aldehydes) in fecal water of Hb- and Bf-fed rats (Hb  and Bf)
Figure 3.  Depletion of carbonyl compounds (including aldehydes) in fecal water of Hb- and Bf-fed rats (Hb and Bf) abolished their differential toxicity towards normal  and preneoplastic cells
Figure 4.  Nrf2 was activated in normal and preneoplastic cells upon exposure to fecal water of Hb- and Bf-fed rats (Hb and Bf)
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