Glucose-dependent insulinotropic polypeptide (GIP) dose-dependently reduces osteoclast differentiation and resorption

At 45 weeks of age, GIPR KO male mice presented with an extreme increase in trabecular bone volume as compared with WT control mice... WT and GIPR KO bone cells highlighted that

In order to understand why the intrinsic mechanical properties of the bone matrix were reduced, we investigated the impact of GIPR de fi ciency on the maturation of the mineral

Our results demonstrate that the gene expression of CD200R, F13A1, TGF, AMAC1, CD163 and MR, all established markers for the alternative differentiation, was

Lysophosphatidic Acid Receptor Type 1 (LPA 1 ) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity * □ S.. Received for publication, November 7, 2013,

At day 14, serum CTX and P1NP levels were elevated in both OVX groups compared with sham groups, indicative of increased bone turnover (Figure 8C); however, clopidogrel treat-

Conclusion: Multinucleated giant cells from cherubism granulomas are CD68 positive cells, which differentiate into macrophages in non-aggressive cherubism and into osteoclasts

Normal erythropoiesis is simulated in two dimensions, and the influence on the output of the model of some parameters involved in cell fate (differentiation, self-renewal, and death

The two most common methods used to induce bone sarcoma in mice involves the injection of a concentrated suspension of murine (allograft) or human (xenograft)