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Enhancer–gene maps in the human and zebrafish genomes using evolutionary linkage conservation

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Academic year: 2021

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Figure

Figure 1. Application of the PEGASUS method and on the complete human and zebrafish genomes
Figure 2. Overlap between PEGASUS CNEs and functional annotations. (A) Percentage of CNEs overlapping histone modification ChIP-seq peaks from embryonic stem cells in human (left) (10) and various developmental stages in zebrafish (right) (36)
Figure 3. Overlap between enhancer-target gene prediction methods. (A) Recall rates (1 – false negative rate)for predicted enhancer regions in the human genome
Figure 4. PEGASUS predicted interactions and TADs. (A) Percentage of CNE-gene associations located in the same TAD as a function of PEAGSUS linkage score
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