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Computer-Aided Drug Target Search

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Computer-Aided Drug Target Search

Y.Z. Chen, Z.R. Li and C.Y. Ung

Abstract—Identification of the unknown targets of drugs,

investigative drugs and herbal ingredients is an important task in drug discovery. It can potentially help in several aspects including: (1) determination of unknown therapeutic mechanism of certain drugs and medicinal herbs, (2) prediction of drug toxicity and side effect, and (3) analysis of protein-mediated pharmacokinetic properties of drugs. Here, a computer-aided drug target search method and its validation studies are presented.

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