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The brain under self-control: modulation of inhibitory and monitoring cortical networks during hypnotic paralysis

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Academic year: 2022

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Suppl. Fig. 1: Activation of inhibitory networks in the right hemisphere. A. Increased activity in inferior frontal gyrus (IFG), posterior middle frontal gyrus (post MFG), and inferior parietal lobule (IPL) was found for NOGO > GO trials in the normal state (irrespective of hands); threshold p <.001 uncorrected. B. No increases was found in these regions for the contrast L-GO > R-GO during hypnosis; threshold p <.001 uncorrected (see text for direct statistical analysis of corresponding ROIs). C. By contrast, feigned left paralysis (L-GO > R-GO in the simulation group) revealed increased activity in the right inferior frontal gyrus (IFG) and inferior parietal lobule (IPL), similar to inhibition during the normal state (see A); threshold p <.001 uncorrected.

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Suppl. Fig. 2: Main effect of hypnotic state. A contrast between all conditions in hypnosis with all conditions in the normal state showed selective increases in the orbitofrontal cortex (OFC) and visual areas (threshold p <.001 uncorrected). The opposite contrast showed an increase in the auditory cortices bilaterally.

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Suppl. Fig. 3: Overlap between regions obtained in the connectivity analysis and in the univariate analysis. Upper panel: The right premotor region showing greater connectivity with right M1 activity in the normal vs hypnotic state (blue blob, threshold p <.01

uncorrected) overlapped with a region activated in the contrast L-PREP > R-PREP during normal state (magenta blob, threshold p <.01 uncorrected). Lower panel: The precuneus region showing greater connectivity with right M1 activity in hypnotic vs normal state (red blob, threshold p<.01 uncorrected) overlapped with activation found in the contrast HYPNO > NORMAL for the L-PREP condition (yellow blob, threshold p <.01

uncorrected).

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