Image Segmentation and 3D reconstruction for improved prediction of the sublimation rate during freeze drying
11
0
0
Texte intégral
(2)
(3) 0123456689
(4)
(5)
(6) !"# $"% &'(%)*+,(+,-%*.%,'/-%0123/)4,/*+%'45(%2((+%(54314,(6%% 27%,'(%8)/(+,/./)%9*::/,,((%;'/)'%/,%<(34,(-%4+6%,'(%0<*)(61<(%-(,%*1,% ',,0=>>*)-?(6/,*</43?105?(->/+6(@?0'0>AB8>/6-CDEF>42*1,>(6/,*</43G*3/)/(-% HII! J
(7) K14+%L+6<M-%9N<)(3% O42</(34%93(:(+,(% K*-M%P/)(+,(%O4<)Q4RGM<(S% L+,*+/*%T13(,% 94<:(+%U*--(33V% HII $W X
(8) Y6/,*</43%Z+/5(<-/,4,%G*3/,[)+/)4%6(%P43[+)/4\%CDEF% ;;;?343/2<(</4?105?(-%%%>%%%U(.?=%]^^D_DE_DE_DE% A8`a=%bcFRF^RbD^FR]FFRc%d0</+,%5(<-/*+e% G</+,%%*+R6(:4+6% BfA=%',,0=>>6@?6*/?*<g>ED?^bbh>AB8CDEF?CDEF?FFcc%. ijklmmnopqrsktsuvwxsypzmjp{zokp{|s}j~opqs~kros &'/-%2**%/-%3/)(+-(6%1+6(<%4%9<(4,/5(%9*::*+-%L,</21,/*+Ra*+9*::(<)/43Ra*+B(,/54,(-R^?D%A+,?%/)(+-(6%% Y6/,*</43%Z+/5(<-/,4,%G*3/,[)+/)4%6(%P43(+)/4%% `4-(6%*+%4%;*<%/+%',,0=>>*)-?(6/,*</43?105?(->/+6(@?0'0>AB8>AB8CDEF.
(9) 01234567946 0
(10)
(11)
(12) 1
(13) 2
(14) 2
(15) 66 6 2 4567 !"#$%%&"''()*(+,*+-.'/0*1223',(450/6*50/6*7818# #. HIJKLMNLKILOPJPQROMJOSMTUMVLWROXPVYWPQROMZRVMQI[VR\LSM [VLSQWPQROMRZMP]LMXY^_QIJPQROMVJPLMSYVQOKMZVLL`LMSVaQOKM M. #. Jf Jf Jf Jf JkM bJ [ R ` ` Q c M de M be M gV X Q W W Q R c M ge M N [ J V J \ Q K O J c M ge M be M hQ X J O R c M ie M jJ V V L X Q c M ge M ge l# m&l-%nmo%#+p#>&&q,m(#9r,morm#lo(#:mr$o+q+.st#C+q,%mro,r+#(,#:+-,o+t#:+-,o+t#!%lqsM. # u<vnl,q#+p#%$m#r+--m4&+o(,o.#lw%$+-"#lo%+omqq+*xl--m4,y&+q,%+*,%# #. z{|}~}. 0
(16)
(17) .
(18)
(19)
(20)
(21)
(22)
(23)
(24)
(25)
(26)
(27) 2
(28)
(29)
(30)
(31)
(32)
(33)
(34)
(35) .
(36) 1
(37)
(38)
(39)
(40)
(41)
(42)
(43)
(44) ~|
(45) 1
(46) 0 2
(47)
(48) 1
(49)
(50) #. #. #. . . 5/9:#!;:<=;>:!;>?# =@!;A#9@BC 9!DB# < !: =!>?#D;!E<=9!:>:#C ?!:FG;!G># <#E>?F;G!>#. # .
(51) 012346431478289 727
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`FaZR ?AHQIF, \QH?NB<JBDIL>?D<QB ?<QOBHI>L?HIHT>@TB=IBKPB=HI<=B>?HOOITBM>HOJNB>?@P=LQBJJBDR T>JT>@TB=?<QOBHI>L? IBKPB=HI<=B=BJ<OIJ>?ITBAL=KHI>L?LAOH=@B=PL=BJG>IT>?ITBD=>BDJHKPOBJFNLLJI>?@ITB J<NO>KHI>L?=HIBR\L=>?JIH?QBF>?\>@<=B IGL QH??>?@!OBQI=L?)>Q=LJQLPE^ !)_>KH@BJ H=BJTLG?F=BP=BJB?I>?@HbcGdGKH??>ILOJHKPOBHAIB=A=BBCBD=E>?@R ?ITBQHJBLA\>@<=B HF, \GHJ<JBDFGT>OBITBJHKPOB>?\>@<=B NGHJP=LQBJJBD<J>?@ITBQL?MB?I>L?HO JTBOAU=HKPBDA=BBC>?@P=LILQLOR. efghijiklmifnogpqirsituivwvinoxxfyrziqon{zpqir|yofxp}i~qfxgikeioiri qpzsion{p}ispp fxgi|h. TBT<@BD>AAB=B?QB>?JHKPOBKL=PTLOL@EGT>QTQH?NBLNJB=MBDI=H?JOHIBJ>?IL=BKH=VHNOE D>AAB=B?IQEQOBPB=AL=KH?QB>I>JITB=BAL=BQOBH=ITHIITB>?AL=KHI>L?L?ITBPL=BJ>CB D>JI=>N<I>L?>JQ=<Q>HOAL=ITBP=LPB=DBJ>@?LAHA=BBCBUD=E>?@P=LQBJJR#OITL<@TKH?ELITB= . . !" # $ #%&"' ( ')*$ +) !& $" #%+ ,!" # *$% -. .#&!,#%- . #.
(53) 012344568909
(54) 5536 9 21
(55) 1516 909 5 136 1
(56)
(57) 56 9 . ,--./,01231,425226-./-/32786912-,39:3;01,3<=.,>9/?/@.,-1>ABC:912?/390/??/6 920168D;2.2?,863/EE=F862 &,6,F>383G18383@262.,FF>,01824275>?2,63/E,?,6;,F ,6,F>383/E912.23;F986@8?,@23G12?,6;,F,--./,0183:1/H242.:18@1F>98?20/63;?86@: ,67912.23;F93/59,8627,.23;5I209842,67:912.2E/.2:-//.F>.2F8,5F2G12.2E/.2:H2.20269F> -./-/327,?291/75,327/691232@?269,98/6/E &8?,@239/,;9/?,980,FF>7292.?862912 -/.238J27839.85;98/6AKCG 6912,5/42=?2698/627H/.L:H231/H2791,98?,@232@?269,98/6 0/;F7D;80LF>,67.2F8,5F>,FF/H.23/F;98/6/E912-/./;339.;09;.2/E9123,?-F2;672. 8642398@,98/6GM2.2H2-./-/32,E;.912.8?-./42?269/E9183920168D;2:H18010/?58623912 ,6,F>383/E912F242F3/E@.2>=9/6239/9127292098/6/E27@23529H22678EE2.2697/?,863G &/.2/42.:H2H8FF31/H91,9:E./?9123;-2.=-8N2F37839.85;98/6/59,8627,3,.23;F9/E 32@?269,98/6:,O#39.;09;.2/E9120,L2?,>52.20/639.;09275>?2,63/E,39/01,3980 ,--./,01GP2H8FF-./4291,9912.20/639.;098/6/59,86270,6E,8.F>H2FF.2-.23269912?,86 E2,9;.23/E912.2,F7.8270,L2G183.23;F9838?-/.9,69:38602912@262.,92739.;09;.2?,>9126 52;327H89186,0/?-;9,98/6,FEF;877>6,?803Q+R#S38?;F,98/6:9/2398?,929129/.9;/389> /E9123,?-F2ATCG86025/91912-/.238J27839.85;98/6,679129/.9;/389>E,09/.2692.869/912 72E86898/6/E912?,339.,63E2..23839,6029/4,-/.EF/H:912,--./,0112.286-./-/3270/;F7 .2?,.L,5F>8?-./42-.278098/6/E9123;5F8?,98/6.,92:H180183,99125,383/E,6>?/72FE/. 912E.22J2=7.>86@-./0233G . UVWXYZ[\]Y^_`Yab`X[Zcdb_`. UVeWf\[[g[`b\h]ai`jhj^[_`Yab`klX`YaY^h_]_` 12E/.?;F,98/68642398@,927869183H/.LH,3,BmHnH?,6689/F3/F;98/6:-.2-,.27E./? 78398FF27H,92.,67?,6689/F-/H72.Q8@?, F7.801SG1248,F32?-F/>27Q9>-2:o : pBNp??:01/99%:%2.?,6>S:H12.2E8FF2786H891O?F/E3,?-F23/F;98/6:,67F/,727 /69/912312F423/E,E.22J2=7.>2.">/q29,BQ2F39,.:2..,33,:-,86SGR/.9120/642698/6,F Q312FE.,?-27SE.22J86@92393:912.2E.8@2.,986@EF;8792?-2.,9;.2H,3720.2,3279/=pBr+,9 oGTr+n?86G 3.2@,.73) R:912-./7;09H,3E8.392D;8F85.,927,9sBr+E/.pB?86,67:9126:91201,?52. -.233;.2H,3.27;0279/Oo',;698F6;0F2,98/6H,3/532.427G12-.233;.2H,39126D;80LF> .2F2,3279/912,9?/3-12.804,F;2:,67912-./7;09H,32D;8F85.,927,9sor+E/.1G/ 0/?-F292912E.22J86@/E912-./7;09:912.2E.8@2.,986@EF;8792?-2.,9;.2H,33;532D;269F> 720.2,3279/spBr+,9oGTr+n?86,6712F7E/.1GR86,FF>:7.>86@H,3-2.E/.?27,9o',: ,67=or+G128692.6,F39.;09;.2/E912.23;F986@0,L2H,3,6,F>J275>?2,63/E,0,6686@ F209./6&80./30/-2Q &:R 9>-2:t;,69, 63-209oo: 8671/426:912 2912.F,673SG . . ! "# $ %$&'! (& # ! "( ) '!" *+ + # ) "* + . uvw.
(58) 012346431478289 727
(59) 4 7889 7 91 4 4 989 7 8491289 7284 973444 973. /0/1234567865369:4:;<97=<>7:?67@><A6BB;957<=78CD7;3456B7 EFGHIJKLKMNOPQKLRMKSTKEURUPVERWWOVRNXIQRMKLVEUXKRERYZMPMV[UXKYK\KYMV[SOKZ] UVEKMI[VOUXKLKUKOTPERUPVEV[UXKWVOKMP^KLPMUOPQ_UPVEPE[OKK^KLOPKLMRTWYKM`aKOKIJK WOVWVMKREPTWOV\KL\KOMPVEV[UXPMUKNXEPb_KIPEJXPNXUXKLKUKNUPVEV[UXKKLSKMQKUJKKE UXKWVOKMRELUXKM_OOV_ELPESMNR[[VYLPMPENY_LKLPEUXKRERYZMPM`cPOMUIUXK !)PTRSKPM WOVNKMMKLUVKEXRENKUXKKLSKMPEPUIUXRUPMWOVNKMMKLUVLKUKNUUXKOKSPVEMJXKOKJKXR\KR YROSKSORLPKEUPEUXKUVWVSORWXZ`#TVESUXKTKUXVLM[VOKLSKLKUKNUPVEIUXK"KUPEKd[PYUKOI JXPNXPMR\RPYRQYKPE( )*eUXK( + TRSK)REPW_YRUPVE*OVSORTFfHgIJRMNXVMKE` XKEI UXPMPE[VOTRUPVEPMTKOSKLUVUXRUNVENKOEPESUXKUVWVSORWXZPUMKY[RELUXKPTRSKNVE\KOUKL PEUVRQPEROZQYRNhRELJXPUKTRWecPS_OKMRRELQg`cOVTUXKOKM_YUPESTRWIUXKWVOKMROK R_UVTRUPNRYYZMKYKNUKLIRMLKMNOPQKLPEFGHIRELRMMXVJEPEcPS_OKMNRELL`. . ijklmnmopqmrstmpuvmowqmwjupxymjzpk{|m}~xx{|~uvjukm~mzpuuj~mm mx{{{mvxj{vm|jukmrilm o}qmr{kz{upj~um~m{m~xjkjupmrstmjzpk{m{x{m{mv~zpju|mpx{mx{x{|{u{vmwymvj{x{um}~~x|lm ovqmj|xjwj~um~m{m|{xj{|mojum~kpxjzj}m|}p{|qm~wpju{vmwym}~ujukm{zmp}}~xvjukm~m {jxmpx{pmojumj{|ql. 7 /01>6;A:;<97<=7:?67>6B;B:49A67:<734BB7:>49B=6>7 XKOKMPMURENKUVTRMMUOREM[KOIIJRMNRYN_YRUKL[OVTUXKR\KORSKWVOKLPTKEMPVE IRM NRYN_YRUKL_MPESKPUXKOUXKTRE_RYRWWOVRNXIVOUXKPTRSKMKSTKEURUPVEUKNXEPb_KIQZTKREM V[UXK[VYYVJPESKb_RUPVEI . . !" # $ #%&"' ( ')*$ +) !& $" #%+ ,!" # *$% -. .#&!,#%- . #.
(60) 012344568909
(61) 5536 9 21
(62) 1516 909 5 136 1
(63)
(64) 56 9 . => 245 89: 1 / ,- .036-70;< ?@ABA CDEFGCBAH@AIDJKABLCMNCLOPDLHCDHCDE?CHABQPMAOIMCB?AJN@HRBALSAOHJKAMTUL OCDVALAADR2JLCWIDOHJPDPWH@AEBJAEMCTABH@JOXDALL8YRCDEEASADELPDH@ASBPEIOH HAQSABCHIBAZRCDEPDH@AEBJAESBPEIOHHPBHIPLJHTWCOHPB[CDESPBPLJHT\RCL?AMMU ]^_`abcdefgbhdijkdclgbjmdbhclicniopigbjmdbmjkgi (LJDNH@AJDWPBQCHJPDPVHCJDAEWBPQJQCNACDCMTLJLRCq#LHBIOHIBAPWH@AEBJAEOCXA?CL H@ADBAOPDLHBIOHAERWPBH@AOCLAPWH@ASBPEIOHPVHCJDAEVT) r=rJNIBAC>UPEPH@JLR LS@ABJOCMSPBAL?ABALHPO@CLHJOCMMTVIJMHJDHPCDsttusttusttvQPBJNJDCMVIMXTOIVAU@A EJQADLJPDPWH@ALS@ABAL?CLO@PLADLPCLHPBASBPEIOAH@ASPBALJwAEJLHBJVIHJPDPVHCJDAE WBPQJQCNALANQADHCHJPD=rJNIBAE>ULL@P?DJDrJNIBAqH@JLSBPOAEIBA?CLJHABCHAEIDHJM H@AEALJBAEKCMIAPWSPBPLJHT?CLBACO@AEU POPDLHBCJDHL?ABAJQSPLAEPDH@ASPLJHJPDPW H@ALS@ABAOADHABLRLPH@CHJDHABSADAHBCHJPDPWH@ASPBAL?CLSPLLJVMARCLJMMILHBCHAEJDrJNIBA qU@JL?CLEPDAJDPBEABHPVAHHABBASBPEIOAH@ABACMLHBIOHIBAPWCWBAAwAxEBJAESBPEIOHR ?@ABAH@ASPBPILLHBIOHIBAJLRNADABCMMTR@JN@MTJDHABOPDDAOHAEU. }. yz{|}~} z}}}zz}}z }z }z} z|}. . . ! "# $ %$&'! (& # ! "( ) '!" *+ + # ) "* + . . .
(65) 012346431478289 727
(66) 4 7889 7 91 4 4 989 7 8491289 7284 973444 973. /01234567489:;8<=4>544=?:8. @ABCDEAFAECAGHDHBIGHAJ@GBKLAMAFJNBOAMBGFAJHBIGPQDFDRRSBAMHIH@A !)BCDEAF F@IQGBGTBELNA P#FBSSLFHNDHAMBGDRNAUBILFQINVWXYZH@BFHAJ@GBKLADSSIQFJDSJLSDHBIGI[ H@AFLRAN\RB]ASFMBFHNBOLHBIGQBH@BGH@A !)BCDEAZ[NICQ@BJ@DGDUANDEARINAFB^AJDGOA _`abcda_efghibgjklackd_mgnljkogl_op_kacajikmgcq_bco_grib_gejp_kljiklgisgtuvwxvgypgckeg xzwzgypg{_b_gi|acjk_egsibg}~hghjonb_gtcgckegl_sgbcpr_egsb__jkoghjonb_gt|mg NAFRAJHBUAS P JIGHNDFHZLFBGEH@AHNDMBHBIGDSDRRNIDJ@ZH@DHBFZCDGLDSS FASAJHBGEDGM CADFLNBGEDFL[[BJBAGHS SDNEAGLCOANI[RINAFZH@AJIGUAGHBIGDS[NAA^BGERNIHIJISDGM, T b_lna_egjkgckgcq_bco_gejcp_a_bgisgvwgypgckegtvwxzgypmgb_lr_dajq_fglgdckg|_gl__kmg OIH@HAJ@GBKLAFCADFLNAMDSDNEANDUANDEARINAFB^ABGH@AJDFAI[, TZQ@BJ@QDFA]RAJHAMZ OAJDLFAI[H@A@BE@ANGLJSADHBIGHACRANDHLNABGH@AJDFAI[JIGHNISSAMGLJSADHBIGPIQAUANZ H@ARINAMBCAGFBIGBFGIHFL[[BJBAGH[INDGDJJLNDHAAFHBCDHBIGI[H@ANAFBFHDGJAHICDFF HNDGF[ANZFBGJADGIH@ANNAKLBNAMRDNDCAHANBFH@AHINHLIFBH [DJHINQ@IFAUDSLABF EAGANDSS IGS NILE@S @ RIH@AFB^AMP RBJDSS LFAMUDSLAFFRDGOAHQAAG PDGMPWYZ DGMH@BFNDGEAHNDGFSDHAFBGHIDSDNEALGJANHDBGH BGH@AUDSLAI[ZDFF@IQGBGTBELNAP. . ¡¢£ ¤¥¦§¨© ª§¥¦¦§¢««¤ ¡¢¬ªª«®«¥¦¢¥ ¡ ¯°±²³±´µ¶±·¸°¹¶±º³»¼³½±¾¸¿±À¯°¿Á¶·¶Â±Ã¯·±²³±Ä¸Å±À¯°Æ¶°ÇÁ¯°¸È±Ã·¶¶ÉÁ°¹Ê±¸°Â±ÄËűÌÍÎϳ±ÐÑ ¤¥ª ¤¥¤ «¥ªÒÓÔ®Õ¢¢¢©¦«Öª¦×©Õ ª¦Ø «Ø¡¢Ö ªÖ ¦ ©©¦ ¢Ù ÐÑ ¤¥ª ¤¥¤ «¥ªÒÓÔ®Õ¢¢¢©¦«Öª¦×©Õ ª¦Ø «Ø¡¢ «¦ ¤Ö ¥ ¤ ©©¦ ¢. #RIFFBOSAFISLHBIGHIH@BFRNIOSACJDGOA[ILGMJICOBGBGEBCDEADGDS FBFDGM.T& FBCLSDHBIGFP G[DJHZDFMAFJNBOAMBGFAJHBIGPZD&FHNLJHLNAI[H@AMNBAMJDVACBE@HOA NAJIGFHNLJHAMLFBGEH@AFLRAN\RB]ASFMBFHNBOLHBIGIOHDBGAM[NICBCDEAFAECAGHDHBIGP#G A]DCRSAI[NAJIGFHNLJHAMFHNLJHLNAZ[INUDN BGEUDSLAFI[RINIFBH ZBFF@IQGBGTBELNAP @A FHIJ@DFHBJDRRNIDJ@LFAM[INH@A&NAJIGFHNLJHBIGQDFUDSBMDHAMDEDBGFHH@AINBEBGDS !) BCDEAZDFILHSBGAMBGTBELNAÚP#ÛÛ]ÛÛ]ÛÛÜCFSBJAQDFBFISDHAM[NICH@A NAJIGFHNLJHAMJLOAZDGMD&FAJHBIGÝTBELNAÚOÞQDFIOHDBGAM[NICH@BFFSBJAZLFBGEDENA \ . ßàá. !" # $ #%&"' ( ')*$ +) !& $" #%+ ,!" # *$% -. .#&!,#%- . #.
(67) 012344568909
(68) 5536 9 21
(69) 1516 909 5 136 1
(70)
(71) 56 9 . ,-./0123/42.56.574-89:6,/,-;321<,-4/=4/0/.,=/40=/1,6>/?:60920@-./6.-4@/4,- 068A32,/,:/028/,B=/-74/=4/0/.,2,6-.-;,26./@6.2,B=6123 &2.23B060?012.;/0//. 1-8=246.5C65A4/0D22.@D;E,:/4/92020,46<6.506863246,B;/,9//.,:/-4656.23 &6825/ 2.@,:/#0/1,6-.-;,26./@74-8,:/F#4/1-.0,4A1,6-.?-7A4,:/41-.7648,:6006863246,BE C65A4/D;9202.23BG/@A06.56825/0/58/.,2,6-.E2.@,:/0A=/4H=6I/30@60,46;A,6-.920 1231A32,/@JC65A4/D1K? /824<2;3BE,:/4/0A3,6.5@60,46;A,6-.1-8=24/072643B9/3396,:,:2, -;,26./@7-4,:/-4656.23 &6825/JC65A4/@K?:608/2.0,:2,,:/F#4/1-.0,4A1,6-. =4/0/4>/08-0,-7,:/7/2,A4/0-7,:/-4656.23028=3/E2.@1-A3@,:/4/7-4/233-92./206/4 2.23B060-7,:/=4-=/4,6/09:61:6.73A/.1/,:/0A;3682,6-.42,/L7-46.0,2.1/E;B2+C# 068A32,6-.-792,/4>2=-473-9,:4-A5:,:/4/1-.0,4A1,/@F#0,4A1,A4/?. . MNOPQRQSTUNVTWNXYQXZQW[\Q]^Q_\`XYaW_b`WNXYQTcc_XT`[dQTeQfghQNiTO\jQkeQbcc\_QlN\mQXZQTQaUN`\QXZQW[\Q ]^QaW_b`Wb_\QTYVQ`eQabc\_ncNo\UaQVNaW_NkbWNXYQNYQMNOPQRkPQQ Q. pqrstuvwxyztuy{. .,:/=4/0/.,9-4<E2./92==4-21::20;//.=4-=-0/@7-4,://0,682,6-.-7;-,:,:/=-4/ 06G/@60,46;A,6-.2.@,:/,-4,A-06,B721,-496,:6.274//G/@46/@028=3/?|-4<606.=4-54/00,- 068A32,/,:/73A6@@B.286106.,:/F#4/1-.0,4A1,/@82,46I?A;0/}A/.,3BE2.23B060-7,:/ >/3-16,B>/1,-407-4,:/92,/4>2=-4@A46.5,:/068A32,6-.9-A3@82</6,=-006;3/,-/0,682,/ ,:/,-4,A-06,B-7,:/028=3/E2.@E,:A0E,-1231A32,/28-4/211A42,/>23A/7-4,:/8200,42.07/4 4/060,2.1/L,:/028/=4-1/@A4/@601A00/@6.~7-4542.A324;/@0-;,26./@;B0=42BH74//G6.5 12.;/2@-=,/@?:/@/0146;/@8/,:-@82B233-92065.67612.,3B68=4->/@76,,6.5-7 /I=/468/.,23@2,296,:4/0=/1,,--,:/4,42@6,6-.238-@/36.5,/1:.6}A/0?|/24/,:/4/7-4/ 1-.>6.1/@,:2,,:/2==4-21::/4/6.-A,36./@1-A3@;//I,4/8/3B;/./761623E=2>6.5,:/92B 7-428-4/4-;A0,@/065.-7,:/74//G/@4B6.5=4-1/00? . qrvutw uy{. +-8=A,2,6-.234/0-A41/09/4/=4->6@/@;B + H+6./12'++" H+%42.,,-"?+?+? J'24,61"BH'+ ))K . . ! "# $ %$&'! (& # ! "( ) '!" *+ + # ) "* + . .
(72) 012346431478289 727
(73) 4 7889 7 91 4 4 989 7 8491289 7284 973444 973. . /0123435367389. : ;<=>?@ABCDE.EFGBHA??CIEGE JAKBAALHMN?OA@HMPQR@JHPHL>OHRMS*JQ?HTRUTJAVHT>P KWMX>VAMO>P?CKBAALHMNVAOJRX?>MXTRM?AYWAMTA?RM@BRTA??@ABKRBV>MTA>MXYW>PHOQ >OOBHZWOA?RKZHR@J>BV>TAWOHT>P?E!WBR@A>MDRWBM>PRK*J>BV>TAWOHT?>MX [HR@J>BV>TAWOHT?\ C]^_`Ca^UbcE :;<*H?>MRC"EF#B?HTTHRC#EF >d>N>e>C=EF[>BBA?HC#E#E.RMOBRPCVA>?WBAVAMO>MX @BAXHTOHRMRKOJAHV@>TORKKBAALHMNRM@BRXWTOVRB@JRPRNQS#?OA@ORe>BX?HV@BRfAX XA?HNMRKKBAALAUXBQHMNTQTPA?E&BQHMN ATJMRPRNQ\ ^C>TTA@OAXE :c;<$XXRMAC EF*H?>MRC"EF[WPPHTJC"EF OAe>BOC*E,>TWWVUHMXWTAXMWTPA>OHRM>?>VAOJRX KRBKBAALAUXBQHMNTQTPAR@OHVHL>OHRME MXW?OBH>P>MX!MNHMAABHMN.JAVH?OBQ"A?A>BTJ \ aCgc_a]`C ^cbU ^aaE :a;<$XXRMAC EF,>M[RTd?O>PC*EUDEF&A[AABC EF*H?>MRC"E V@>TORKf>TWWVUHMXWTAX ?WBK>TAKBAALHMNRMHMOABU>MXHMOB>UfH>PJAOABRNAMAHOQE!WBR@A>MDRWBM>PRK *J>BV>TAWOHT?>MX[HR@J>BV>TAWOHT?\ bC \c_ `C b]U ]^E :g;<*H?>MRC"EF[>BBA?HC#E#EF.>@RLLHC%E.EFRf>hB>C(EF$XXRMAC EF,HO>PAU[BRf>BRMAC.E .J>B>TOABHL>OHRMRKOJAV>??OB>M?KABRKPQR@JHPHLAX@BRXWTO?Z>?AXRMiUB>QVHTBRU TRV@WOAXORVRNB>@JQHV>NA?E&BQHMN ATJMRPRNQ\ ]Ccg_^`CjccUjc^E :b;<#B?HTTHRC#EF @>B>fHNM>C#E.EF*H?>MRC"EF[>BBA?HC#E#E)A>?WBHMN>MX@BAXHTOHMN@RBA ?HLAXH?OBHZWOHRMRKKBAALAUXBHAX?RPWOHRM?E&BQHMN ATJMRPRNQ\ ^CHM@BA??E&$ S \E \^\k\]c]cjc]E\ ^E ac\\a :];<.>@RLLHC%E.EF[RTT>BXRC(EF[>BBA?HC#E#EF*H?>MRC"E.RV@WOABU>HXAX@BR@ABOQ A?OHV>OHRMRKVHOTJBRU@>BOHTPA?HM@>TdAXUZAX?KRBKBAALAUXBQHMN>@@PHT>OHRM?E M *BRTAAXHMN?RK\ MOABM>OHRM>P&BQHMN QV@R?HWVC(HKWCD>@>MC#WNW?O]U \C\ bF @>@AB#UaUcE :^;<GHMP>Q?RMC(E&EFlRBXPAQC E&E F&BAeC)E E"AVRfHMN?J>XRe?KBRVHV>NA?W?HMN BAOHMAmE M*BRTAAXHMN?RK \OJ.RPRB>MX V>NHMN.RMKABAMTAC TROO?X>PAC#BHLRM>C D>MW>BQ\\F]cU]jE :j;<(R?JHV>ClEF&RC(EF >d>N>e>C=E V@>TORKHTAVRB@JRPRNQRMXA?HNM?@>TARK @J>BV>TAWOHT>PKBAALAUXBQHMNEDRWBM>PRK*J>BV>TAWOHT>P THAMTA?\ bC \g_b`C j\U jccE. . nop. !" # $ #%&"' ( ')*$ +) !& $" #%+ ,!" # *$% -. .#&!,#%- . #.
(74)
Documents relatifs
The z-position (in the frame of the current position of the endoscope) of each point on the surface of the organs is individually modelled as a Gaussian distribution (mean and
Conic sectors that are useful for the analysis of multivariable feedback systems are presented in this paper. The conic sectors are analogous to those
3°) L’homme espagnol, tel que peut l’observer le poète est à son tour évoqué dans ces poèmes philosophiques. Reprenant le mythe biblique de Caïn et Abel, le poème X synthétise
Additional tests further confirm this analysis: i) varying the velocity of the air flux between 1.6 and 5.4 m.s -1 the initial velocity in the very first time varied
The contribution of this paper is therefore to provide a model predictive control (MPC) framework, as applied in [9], to minimize under constraints the drying
Image Segmentation Applied to the Investigation of Craquelure Domains in Paintings?. Andrea Arsiccio, Amelia Carolina Sparavigna,
Attempts to freeze a gel (1204; -18OC) without exchanging the solvent showed that EtOH-enriched liquid was entrapped inside the frozen gel. During freeze drying at low pressure
To initialize the process, we build a list of faces sorted by increasing external variation. The first face in the list has the lowest external variation. In fact, each face
