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In vitro emergence of rifampicin resistance in Propionibacterium acnes and molecular characterization of mutations in the rpoB gene

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Academic year: 2021

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Figure 1. Progressive emergence of rifampicin (RIF) resistance in P. acnes using two different inocula (a) and in combination with 0.25 × MIC of daptomycin (DAP), levofloxacin (LVX), clindamycin (CLI) or penicillin G (PEN) using an inoculum of 10 6 cfu/mL
Table 2. Amino acid substitutions found in rifampicin-resistant P. acnes isolates Isolate Rifampicin MIC(mg/L)a Amino acid substitution GenBank accessionnumber
Figure 2. Amino acid sequence comparison of clusters I and II of the rpoB gene of E. coli, M

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