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Toxicological profile of calcium carbonate nanoparticles for industrial applications

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Toxicological profile of calcium carbonate nanoparticles for

industrial applications

Authors

Marta d’Amora, Freddy Liendo, Fabio A Deorsola, Samir Bensaid, Silvia Giordani

Publication date

2020/3/6

Journal

Colloids and Surfaces B: Biointerfaces

Pages

110947

Publisher

Elsevier

Description

Calcium carbonate nanoparticles (CaCO3NPs) derived from CO2 are promising materials for

different industrial applications. It is imperative to understand their toxicological profile in biological systems as the human and environmental exposures to CaCO3NPs increases with

growing production. Here, we analyse the cytotoxicity of CaCO3NPs synthesised from a CaO

slurry on two cell lines, and in vivo on zebrafish (Danio Rerio). Our results demonstrate the CaCO3NPs in vitro safety as they do not cause cell death or genotoxicity. Moreover, zebrafish

treated with CaCO3NPs develop without any abnormalities, confirming the safety and

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